(1) At saturating concentrations of ER, plasmids bearing one, two, and four EREs in tandem bound approximately one, two, and four dimeric ER molecules, respectively.
(2) Interestingly, each of these fragments had a perfect palindromic estrogen responsive element (ERE) (GGT-CANNNTGACC).
(3) These data suggest that flanking DNA sequences may exert a significant effect on the activity of EREs as hormone-dependent transcription activators.
(4) In 11 spontaneously breathing patients with chronic obstructive pulmonary disease (COPD) in acute ventilatory failure, we measured the total inspiratory (WItot) and total resistive (WI + Eres) work rate of breathing, together with lung mechanics (dynamic pulmonary elastance and inspiratory and expiratory pulmonary flow resistance).
(5) This element binds to the estrogen receptor in vitro as assessed by gel retardation assay similar to the vitellogenin gene ERE.
(6) The two polypeptides are different as judged by peptide mapping, and only the 85-kDa polypeptide can be cross-linked to the bromodeoxyuridine-substituted synthetic ERE by UV irradiation.
(7) Two methods have been suggested for the calculation of pHapp and the loss of activity on particle preparation, these methods are based on the use of the ERE in conjunction with experimental data.
(8) These results suggest that the ability of ER and TR to functionally discriminate between an ERE and a TRE is a result of dimerization of their DBDs.
(9) The presence of the biologically active hER is confirmed in co-injection experiments, in which HEO is co-introduced with a CAT reporter gene under the control of a vitellogenin promoter containing or lacking the ERE.
(10) Gene transfer experiments using estrogen-responsive cells have shown that the 13 bp perfect palindromic element GGTCACTGTGACC found upstream of the Xenopus laevis vitellogenin gene A2 promoter mediates hormonal stimulation and thus, was called the estrogen-responsive element (ERE).
(11) The ovalbumin promoter half-palindromic ERE motif located close to the TATA box was required for the activity of the distal DH3 ERE, but could be replaced by the binding sites of other transactivators.
(12) The equilibrium constant for the redox equilibration of fatty acid synthase in a glutathione redox buffer is 15 mM (Ered + GSSG in equilibrium Eox + 2GSH).
(13) When sequenced, these elements showed remarkable diversity and were different from the consensus vitellogenin A2 ERE.
(14) However at 32 degrees C Ta, there was an increase in rectal temperature in response to haloperidol application; this hyperthermia was due to a decrease in both the ear blood flow and respiratory evaporative heat loss (Eres).
(15) The affinity of estradiol binding to receptors was reduced only 2- and 5-fold, respectively, in the double and quadruple Cys to Ala mutants, and estradiol was an effective stimulator of transcription from an estrogen-responsive reporter gene [(ERE)2-TATA-CAT].
(16) A stimulatory estrogen response element (ERE) was localized to a 32-bp region between -547 and -516 bp.
(17) In these genes, two ERE homologues, which have only low, if any, regulatory capacity on their own, act synergistically to achieve high estrogen inducibility.
(18) "Gnnmph, I can't 'ave it 'ere, I 'aven't 'ad my enema," wails a labouring housewife, straining fruitlessly on a communal tenement bog as horrified neighbours look on in their rollers.
(19) This ERE also mediated down-regulation by progestins in the presence of the progesterone receptor, even though it has no progesterone receptor binding ability.
(20) This 67 bp region contains a consensus for the core sequence of the glucocorticoid responsive element (GRE) and the estrogen responsive element (ERE).
(n.) The native form of a metal, whether free and uncombined, as gold, copper, etc., or combined, as iron, lead, etc. Usually the ores contain the metals combined with oxygen, sulphur, arsenic, etc. (called mineralizers).
(n.) A native metal or its compound with the rock in which it occurs, after it has been picked over to throw out what is worthless.
(n.) Metal; as, the liquid ore.
Example Sentences:
(1) Three long-time and two ore three respectively shorter observations of scoliotics with syringomyelia are presented and the pertinent literature is discussed including the complex etiopathogenesis.
(2) His views were backed up by a recent survey in newspaper Il Sole 24 Ore , which listed Sicily as the worst region in Italy in quality-of-life rankings, and Palermo as the worst within the region.
(3) But Zhang described $9m of that as legitimate profit from an iron-ore deal, adding: "There are plenty of reasons to argue against the rest of the amount."
(4) Forrest noted Fortescue’s rivals Rio Tinto and BHP Billiton had a break-even price of about US$30 a tonne, and the latter announced plans on Tuesday to slash costs at its WA iron ore mines to US$16 a tonne.
(5) These could include prize iron ore mines in the Pilbara region of Western Australia.
(6) Fibrous actinolite was found in unexpanded Montana vermiculite ore at a maximum concentration of 2.0%.
(7) The main works in the mine were classified as mining, dressing of ores, refining, and clerical work.
(8) Hair arsenic analysis in people living in two locations near an ore smelter and a refinery indicated high-levels compared to those of individuals residing in nonpolluted areas.
(9) In the study area, Cu and Zn emanate from sewage and boat slips (antifouling paints), while Zn probably also originates from coolant water from an electricity power generating station and iron ore exporting facilities.
(10) Microorganisms were studied by capillary microscopy in the surface layer of ooze and in the bottom layer of water in the ore field of the lake Krasnoye.
(11) For example, a post-consumer automotive catalyst has a concentration of platinum group metals (like platinum, palladium and rhodium) more than 100 times higher than in natural ores.
(12) In addition to the financial costs due to lost output and repairs at the mine, which accounts for about 10% of Brazil’s iron ore exports, BHP and Vale are expected to face steep fines as well as lawsuits at a time when iron ore prices are at their lowest point in a decade.
(13) In order to provide drainage, the catheter should be advanced under fluoroscopic control into one of the major radicles ore preferably into the distal common duct beyond the point of obstruction.
(14) Strikes are also under way at gold and iron ore mines and production of 2,000 cars was lost after a wildcat strike at the Toyota plant in Durban.
(15) Facebook Twitter Pinterest The Fortescue Solomon iron ore mine in the Valley of the Kings.
(16) The hazards covered are: accidents, dust (including poisoning by certain ores), high temperature and humidity, noise and vibration, toxic gases, and miscellaneous other hazards.
(17) Forrest described the job cuts, from a workforce of about 4,500, as “personally tragic” and “heartbreaking”, but said the iron ore company was still making profits, with a break-even price of about US$39 a tonne.
(18) An elaborated model for the mining of ores, the applicability to underground workers and the comparability of loading quantities, based on the dosage measurement, are described.
(19) A ustralians are routinely being told that hefty mining taxes would hinder the country’s largest exports of coal and iron ore.
(20) While the iron ore sector went from representing 1.1% of GDP to its current share of 3.9%, the coal industry went from 1.1% of GDP to now representing about 1.4%.