(1) At saturating concentrations of ER, plasmids bearing one, two, and four EREs in tandem bound approximately one, two, and four dimeric ER molecules, respectively.
(2) Interestingly, each of these fragments had a perfect palindromic estrogen responsive element (ERE) (GGT-CANNNTGACC).
(3) These data suggest that flanking DNA sequences may exert a significant effect on the activity of EREs as hormone-dependent transcription activators.
(4) In 11 spontaneously breathing patients with chronic obstructive pulmonary disease (COPD) in acute ventilatory failure, we measured the total inspiratory (WItot) and total resistive (WI + Eres) work rate of breathing, together with lung mechanics (dynamic pulmonary elastance and inspiratory and expiratory pulmonary flow resistance).
(5) This element binds to the estrogen receptor in vitro as assessed by gel retardation assay similar to the vitellogenin gene ERE.
(6) The two polypeptides are different as judged by peptide mapping, and only the 85-kDa polypeptide can be cross-linked to the bromodeoxyuridine-substituted synthetic ERE by UV irradiation.
(7) Two methods have been suggested for the calculation of pHapp and the loss of activity on particle preparation, these methods are based on the use of the ERE in conjunction with experimental data.
(8) These results suggest that the ability of ER and TR to functionally discriminate between an ERE and a TRE is a result of dimerization of their DBDs.
(9) The presence of the biologically active hER is confirmed in co-injection experiments, in which HEO is co-introduced with a CAT reporter gene under the control of a vitellogenin promoter containing or lacking the ERE.
(10) Gene transfer experiments using estrogen-responsive cells have shown that the 13 bp perfect palindromic element GGTCACTGTGACC found upstream of the Xenopus laevis vitellogenin gene A2 promoter mediates hormonal stimulation and thus, was called the estrogen-responsive element (ERE).
(11) The ovalbumin promoter half-palindromic ERE motif located close to the TATA box was required for the activity of the distal DH3 ERE, but could be replaced by the binding sites of other transactivators.
(12) The equilibrium constant for the redox equilibration of fatty acid synthase in a glutathione redox buffer is 15 mM (Ered + GSSG in equilibrium Eox + 2GSH).
(13) When sequenced, these elements showed remarkable diversity and were different from the consensus vitellogenin A2 ERE.
(14) However at 32 degrees C Ta, there was an increase in rectal temperature in response to haloperidol application; this hyperthermia was due to a decrease in both the ear blood flow and respiratory evaporative heat loss (Eres).
(15) The affinity of estradiol binding to receptors was reduced only 2- and 5-fold, respectively, in the double and quadruple Cys to Ala mutants, and estradiol was an effective stimulator of transcription from an estrogen-responsive reporter gene [(ERE)2-TATA-CAT].
(16) A stimulatory estrogen response element (ERE) was localized to a 32-bp region between -547 and -516 bp.
(17) In these genes, two ERE homologues, which have only low, if any, regulatory capacity on their own, act synergistically to achieve high estrogen inducibility.
(18) "Gnnmph, I can't 'ave it 'ere, I 'aven't 'ad my enema," wails a labouring housewife, straining fruitlessly on a communal tenement bog as horrified neighbours look on in their rollers.
(19) This ERE also mediated down-regulation by progestins in the presence of the progesterone receptor, even though it has no progesterone receptor binding ability.
(20) This 67 bp region contains a consensus for the core sequence of the glucocorticoid responsive element (GRE) and the estrogen responsive element (ERE).
Sere
Definition:
(a.) [OE. seer, AS. sear (assumed) fr. searian to wither; akin to D. zoor dry, LG. soor, OHG. sor/n to to wither, Gr. a"y`ein to parch, to dry, Skr. /ush (for sush) to dry, to wither, Zend hush to dry. Ã152. Cf. Austere, Sorrel, a.] Dry; withered; no longer green; -- applied to leaves.
(a.) Dry; withered. Same as Sear.
(n.) Claw; talon.
Example Sentences:
(1) GTT proved to be normal in all the women; there sere no signs pointing to the possibility of prediabetic state.
(2) Ini tidak hanya menyebabkan frekuensi banjir yang lebih sering, tapi juga berpotensi merusak saluran air bersih terpipa maupun sistem pembuangan air kotor.
(3) The estrogen-induced hepatic synthesis of the serine-rich protein, phosvitin, in chickens is accompanied by an increase in the serine acceptance of total hepatic tRNA, which is limited to two sering isoacceptors.
(4) Some of the neutral fractions that have been demonstrated to cause tumor promotion in mice pretreated with 7,12-dimethylbenz-[aA1ANTHRACENE sere inactive as tumor initiators.
(5) Control sere (normal serum, anti-ova or anti-S or anti-P sera are inefficient.
(6) Dapat dimengerti bahwa kita sering kali menggantungkan harapan di pundak para politisi, tapi berharap politik akan dapat mengubah status quo secara mendasar hanyalah khayalan.
(7) The serological cross-reactions of T. mutans (Ationg) with other strains of T. mutans isolated in East and South Africa sere investigated as were the serological cross-reaction of T, mutans (Aitong) and other species of Theileria.
(8) The serine-glycine interconversion is catalyzed by the folic acid containing enzyme sering hydroxymethyltransferase, and a deficiency of this vitamin decreases the effectiveness of serine in meeting the chick's dietary need for glycine.
(9) Yang tidak terlihat bahkan lebih buruk: Jakarta tenggelam dengan kecepatan 20cm setiap tahun Banjir juga bertambah sering: dari yang awalnya hanya setiap lima tahun sekali, menjadi banjir di setiap musim hujan, dan kini banjir hadir saat hujan turun lebih dari tiga jam.
(10) These extracts sere fractionated by micropreparative electrophoresis on polyacrylamide gels.
(11) These probably caused inflammatory changes which sere reflected in an increase of the cellular content and high enzyme levels (acid phosphatase and 5-nucleotidase) of the synovial fluid.
(12) The maximal changes in aerobic metabolism and body temperature sere similar, while the changes in lactate, potassium, hydrogen ion and catecholamine concentrations were smaller than those observed following halothane.
(13) These three instruments are based on the principle of absorption of infra-red radiation in the 9.5 um region and are the Drager Alcotest 7110, Siemens Alcomat V5.2F and Seres Ethylometre 679.
(14) Newly synthesized calsequestrin and adenosine triphosphatase (ATPase) sere isolated by antibody precipitation, followed by separation of the precipitates in SDS-polyacrylamide gels.