(1) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(2) The results of the evaluation confirm that most problems seen by first level medical personnel in developing countries are simple, repetitive, and treatable at home or by a paramedical worker with a few safe, essential drugs, thus avoiding unnecessary visits to a doctor.
(3) Nucleotide, which is essential for catalysis, greatly enhances the binding of IpOHA by the reductoisomerase, with NADPH (normally present during the enzyme's rearrangement step, i.e., conversion of a beta-keto acid into an alpha-keto acid, in either the forward or reverse physiological reactions) being more effective than NADP.
(4) Community involvement is a key element of the Primary Health Care (PHC) approach, and thus an essential topic on a course for managers of Primary Health Care programmes.
(5) No significant fatty acid binding by proteins was detected in S. cerevisiae, even when grown on a fatty acid-rich medium, thus indicating that such proteins are not essential to fatty acid metabolism.
(6) The UK's standard position on ICC indictees is to avoid all contact unless "essential".
(7) In spite of important differences in size, chemical composition, polymer density, and configuration, biological macromolecules indeed manifest some of the essential physical-chemical properties of gels.
(8) Most cis AB sera have anti-B activity, essentially at 4 degrees C. In saliva A and H substances are found in normal amounts but B substance is only evidenced by inhibition of autologous cells agglutination.
(9) Treatment with trypsin gave essentially one radioactive peptide, the active site peptide, of approximately 2300 molecular weight.
(10) We conclude that this enzyme is essentially identical to the native enzyme and should be very useful in the future study of this important hydroxylase.
(11) Thus serum ionized calcium in untreated essential hypertensive patients may predict the blood pressure response to the slow calcium channel blocker verapamil.
(12) The effects of supervised mild aerobic exercise at the work load of the blood lactate threshold for 10 weeks on serum lipids and apolipoproteins were studied in 24 patients with essential hypertension.
(13) No other essential regulatory sequence is located further upstream.
(14) Based on the results of the Community AIM Exploratory Action, further collaborative work is required at EEC level to create an Integrated Health Information Environment (IHE) allowing essentially for integration, modularity and security.
(15) Ovarian vein sampling for androgen was essential in locating this patient's microscopic tumor.
(16) After approximately 20 in vitro passages, Chinese hamster kidney (CHK) cell cultures transformed upon exposure to different strains of SV 40 can show a diploid modal chromosome number of 22 with chromosome counts exclusively or essentially in the diploid range (20-25).
(17) An official from Cafcass, the children and family court advisory service, tried to persuade the child in several interviews, but eventually the official told the court that further persuasion was inappropriate and essentially abusive.
(18) Of 55 new open reading frames analysed by gene disruption, three are essential genes; of 42 non-essential genes that were tested, 14 show some discernible effect on phenotype and the remaining 28 have no overt function.
(19) Essential characteristics of the composite bone cement included a homogeneous and uniform fiber distribution, and a minimal increase in apparent viscosity of the polymerizing cement.
(20) The median blood levels were lower in hyperacidic subjects and higher in hypoacidic patients; the urinary excretion of the digitalis compound showed no essential differences.
Principle
Definition:
(n.) Beginning; commencement.
(n.) A source, or origin; that from which anything proceeds; fundamental substance or energy; primordial substance; ultimate element, or cause.
(n.) An original faculty or endowment.
(n.) A fundamental truth; a comprehensive law or doctrine, from which others are derived, or on which others are founded; a general truth; an elementary proposition; a maxim; an axiom; a postulate.
(n.) A settled rule of action; a governing law of conduct; an opinion or belief which exercises a directing influence on the life and behavior; a rule (usually, a right rule) of conduct consistently directing one's actions; as, a person of no principle.
(n.) Any original inherent constituent which characterizes a substance, or gives it its essential properties, and which can usually be separated by analysis; -- applied especially to drugs, plant extracts, etc.
(v. t.) To equip with principles; to establish, or fix, in certain principles; to impress with any tenet, or rule of conduct, good or ill.
Example Sentences:
(1) Stress is laid on certain principles of diagnostic research in the event of extra-suprarenal pheochromocytomas.
(2) However, as the same task confronts the Lib Dems, do we not now have a priceless opportunity to bring the two parties together to undertake a fundamental rethink of the way social democratic principles and policies can be made relevant to modern society.
(3) To a supporter at the last election like me – someone who spoke alongside Nick Clegg at the curtain-raiser event for the party conference during the height of Labour's onslaught on civil liberties, and was assured privately by two leaders that the party was onside about civil liberties – this breach of trust and denial of principle is astonishing.
(4) The White House denied there had been an agreement, but said it was open in principle to such negotations.
(5) Using the MTT assay and analyzing the data using the median-effect principle, we showed that synergistic cytotoxic interactions exist between CDDP and VM in their liposomal form.
(6) The heretofore "permanently and totally disabled versus able-bodied" principle in welfare reforms is being abbandoned.
(7) The binding follows the principle of isotope dilution in the physiologic range of vitamin B12 present in human serum.
(8) The principle of the liquid and solid two-phase radioimmunoassay and its application to measuring the concentrations of triiodothyronine and thyroxine of human serum in a single sample at the same time are described in this paper.
(9) Spectrophotometric tests for the presence of a lysozyme-like principle in the serum also revealed similar trends with a significant loss of enzyme activity in 2,4,5-T-treated insects.
(10) All these strains produced an enterotoxic principle, antigenically related to cholera coli family of enterotoxins, as detected by latex agglutination and immuno-dot-blot tests.
(11) The basic principle of the resonant tool, its adaptation for surgery, the experimental results of its use in animals, and clinical experience are reported.
(12) It seems tragic, then, that so little of these principles transfer over to the container in which the work is done.
(13) This conception of the city as an expression of both regal power and social order, guided by cosmological principles and the pursuit of yin-yang equilibrium, was unlike anything in the western tradition.
(14) The general principles of bypass surgery as they affect the cerebral circulation are reviewed.
(15) The interest of this view resides in the resulting general principle of classification and interpretation of all forms of disease, giving rise to an "existenialistic pathology".
(16) Eight of the UK's biggest supermarkets have signed up to a set of principles following concerns that they were "failing to operate within the spirit of the law" over special offers and promotions for food and drink, the Office of Fair Trading has said.
(17) Although the general guiding principle of pharmacotherapy for anxiety disorders--the lowest effective dose for the shortest possible time--remains, this rule should not interfere with the judicious use of medications as long as the benefits justify it.
(18) In older stages, the cervical joints rotate according to geometric and lever arm principles.
(19) Spain’s constitutional court responded by unanimously ruling that the legislation had ignored and infringed the rules of the 1978 constitution , adding that the “principle of democracy cannot be considered to be separate from the unconditional primacy of the constitution”.
(20) The principles and practice of aneasthesia for patients having coronary bypass grafts are discussed.