(1) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
(2) It is argued that this process drove the evolution of present 5' and 3' splice sites from a subset of proto-splice sites and also drove the evolution of a more efficient splicing machinery.
(3) It has been possible to observe the evolution of their lesions.
(4) Gradual evolutionary change by natural selection operates so slowly within established species that it cannot account for the major features of evolution.
(5) The early absolute but transient dependence of these A-MuLV mast cell transformants on a fibroblast feeder suggests a multistep process in their evolution, in which the acquisition of autonomy from factors of mesenchymal cell origin may play an important role.
(6) The evolution and function of multiple forms of a given photosynthetic pigment in vivo are discussed.
(7) Evolution of serological procedures was continuous through this period but without clear evidence of improvement in performance of antibody detection although performance in the UK appears to be comparable with that elsewhere.
(8) With the successful culture of these tissues, their development, biochemistry, and physiology, potentially of great importance in understanding early vertebrate evolution, can be better understood.
(9) This situation highlights the potential importance of molecules with different inheritance patterns in elucidating complex cases of reticulate evolution.
(10) The evolution of tissue damage in compressive spinal cord injuries in rats was studied using an immunohistochemical technique and by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) analysis.
(11) Republican presidential hopeful Scott Walker has refused to say whether he believes in the theory of evolution, arguing that it is “a question a politician shouldn’t be involved in one way or the other”.
(12) It is mentioned that the lack of a valuable status for industrial physicians may adversely affect the evolution of training programs in Switzerland.
(13) Assessment of a predictive factor for the evolution of the disease is not yet possible.
(14) These studies indicate that, in three models of acute liver injury, the net influx of calcium across the plasma membrane is increased early in the evolution of the injury before irreversible damage occurs.
(15) The strong homology of mammalian L27' to yeast L29 suggests a function which has been conserved throughout evolution, and thus L27' may also be involved in peptidyl transferase activity.
(16) The diversity of the non-Hodgkin's groups, the continued evolution of histopathologic classifications, and the great frequency of advanced disease in the lymphocytic subgroups make the Ann Arbor classification of only limited value for the non-Hodgkin's lymphomas.
(17) We show how this model would explain the perinatal or infantile onset of the disease, the variability of the rate of evolution between the different SMA forms, and the fact that motoneuron loss is much more dramatic in SMA than in even advanced cases of myopathy.
(18) Evolution into acute myeloid leukemia occurred in 11 patients.
(19) On evaluation of the time evolution of the symptoms we found that most patients continued to show them until September each year.
(20) The evolution with time of cardio-respiratory variables, blood pressure and body temperature has been studied on six males, resting in semi-nude conditions during short (30 min) cold stress exposure (0 degree C) and during passive recovery (60 min) at 20 degrees C. Passive cold exposure does not induce a change in HR but increases VO2, VCO2, Ve and core temperature Tre, whereas peripheral temperature is significantly lowered.
Principle
Definition:
(n.) Beginning; commencement.
(n.) A source, or origin; that from which anything proceeds; fundamental substance or energy; primordial substance; ultimate element, or cause.
(n.) An original faculty or endowment.
(n.) A fundamental truth; a comprehensive law or doctrine, from which others are derived, or on which others are founded; a general truth; an elementary proposition; a maxim; an axiom; a postulate.
(n.) A settled rule of action; a governing law of conduct; an opinion or belief which exercises a directing influence on the life and behavior; a rule (usually, a right rule) of conduct consistently directing one's actions; as, a person of no principle.
(n.) Any original inherent constituent which characterizes a substance, or gives it its essential properties, and which can usually be separated by analysis; -- applied especially to drugs, plant extracts, etc.
(v. t.) To equip with principles; to establish, or fix, in certain principles; to impress with any tenet, or rule of conduct, good or ill.
Example Sentences:
(1) Stress is laid on certain principles of diagnostic research in the event of extra-suprarenal pheochromocytomas.
(2) However, as the same task confronts the Lib Dems, do we not now have a priceless opportunity to bring the two parties together to undertake a fundamental rethink of the way social democratic principles and policies can be made relevant to modern society.
(3) To a supporter at the last election like me – someone who spoke alongside Nick Clegg at the curtain-raiser event for the party conference during the height of Labour's onslaught on civil liberties, and was assured privately by two leaders that the party was onside about civil liberties – this breach of trust and denial of principle is astonishing.
(4) The White House denied there had been an agreement, but said it was open in principle to such negotations.
(5) Using the MTT assay and analyzing the data using the median-effect principle, we showed that synergistic cytotoxic interactions exist between CDDP and VM in their liposomal form.
(6) The heretofore "permanently and totally disabled versus able-bodied" principle in welfare reforms is being abbandoned.
(7) The binding follows the principle of isotope dilution in the physiologic range of vitamin B12 present in human serum.
(8) The principle of the liquid and solid two-phase radioimmunoassay and its application to measuring the concentrations of triiodothyronine and thyroxine of human serum in a single sample at the same time are described in this paper.
(9) Spectrophotometric tests for the presence of a lysozyme-like principle in the serum also revealed similar trends with a significant loss of enzyme activity in 2,4,5-T-treated insects.
(10) All these strains produced an enterotoxic principle, antigenically related to cholera coli family of enterotoxins, as detected by latex agglutination and immuno-dot-blot tests.
(11) The basic principle of the resonant tool, its adaptation for surgery, the experimental results of its use in animals, and clinical experience are reported.
(12) It seems tragic, then, that so little of these principles transfer over to the container in which the work is done.
(13) This conception of the city as an expression of both regal power and social order, guided by cosmological principles and the pursuit of yin-yang equilibrium, was unlike anything in the western tradition.
(14) The general principles of bypass surgery as they affect the cerebral circulation are reviewed.
(15) The interest of this view resides in the resulting general principle of classification and interpretation of all forms of disease, giving rise to an "existenialistic pathology".
(16) Eight of the UK's biggest supermarkets have signed up to a set of principles following concerns that they were "failing to operate within the spirit of the law" over special offers and promotions for food and drink, the Office of Fair Trading has said.
(17) Although the general guiding principle of pharmacotherapy for anxiety disorders--the lowest effective dose for the shortest possible time--remains, this rule should not interfere with the judicious use of medications as long as the benefits justify it.
(18) In older stages, the cervical joints rotate according to geometric and lever arm principles.
(19) Spain’s constitutional court responded by unanimously ruling that the legislation had ignored and infringed the rules of the 1978 constitution , adding that the “principle of democracy cannot be considered to be separate from the unconditional primacy of the constitution”.
(20) The principles and practice of aneasthesia for patients having coronary bypass grafts are discussed.