(n.) The act rendering more violent or bitter; the state of being exacerbated or intensified in violence or malignity; as, exacerbation of passion.
(n.) A periodical increase of violence in a disease, as in remittent or continious fever; an increased energy of diseased and painful action.
Example Sentences:
(1) Circuit weight training does not exacerbate resting or exercise blood pressure and may have beneficial effects.
(2) In patients with acute exacerbations of chronic obstructive pulmonary disease, although either sympathomimetic or anticholinergic therapy provides bronchodilatation, no further benefit could be demonstrated from combination therapy.
(3) We report a case of chronic recurrent polymyositis associated with increasing antibody titers of coxsackievirus A9 in serum during clinical exacerbations.
(4) The data indicate that activated helper T cells are required and sufficient to give rise to the inflammatory infiltrates that are characteristic of the inflammations and exacerbations in human rheumatoid arthritis.
(5) The development of renal insufficiency during enalapril therapy may be exacerbated by concomitant diuretic therapy and should raise the suspicion of underlying transplant renal-artery stenosis.
(6) A lysosomal membrane labilizer, vitamin A, exacerbated the cartilage pathology, whereas a stabilizer, cortisone, retarded it.
(7) The utility of a life charting approach is emphasized in delineating past and present course of illness, considering the relevance of cycling pattern and past treatment efficacy in selection of present pharmacological interventions, and helping to formulate a multifactorial concept of the interplay of biological and psychosocial factors in the evolution or exacerbation of mood disorders.
(8) Endotoxins in plasma were monitored during treatment in 18 patients hospitalised for acute exacerbation of Crohn's disease: systemic endotoxaemia was found on admission in all but one.
(9) Exacerbation of inflammation due to repeated traumatization of the oesophagus wall was accompanied by proliferation of the epithelial layers.
(10) Pyoderma gangrenosum is a poorly understood disease characterized by exacerbations and remissions of morphologically unique skin ulcers.
(11) A complex scheme of prophylaxis of exacerbation and progression of chronic bronchopulmonary diseases in children was developed.
(12) The clinical aspects with remission and exacerbation are discussed.
(13) We designed the present study to evaluate the efficacy and safety of cefaclor in the treatment of acute exacerbations of chronic bronchitis in cigarette smokers.
(14) It was demonstrated that neither enflurane nor halothane exacerbates a pre-existing susceptibility to seizure activity and that both these inhalation anaesthetics are suitable for cases suffering from cerebral convulsive disorders.
(15) We conclude that myoglobinuria, of a degree insufficient to cause renal failure itself, can interact with renal ischemia to significantly exacerbate the renal damage produced.
(16) These lymph node reactions could have likely been a part of the so called early exacerbation.
(17) Hyperglycemia exacerbates neurologic damage in clinical and experimental central nervous system ischemia.
(18) Anticoagulation may exacerbate possible tendencies for an ischemic infarction to become hemorrhagic.
(19) (4) Symptoms are exacerbated by a research ward that is disruptive to the community.
(20) This injury was exacerbated to grade 4 (p less than 0.05) following reperfusion but was almost completely healed 24 h later.
Intensification
Definition:
(n.) The act or process of intensifying, or of making more intense.
Example Sentences:
(1) We have addressed the effect of late intensification with autologous bone marrow transplantation on SCLC through a randomized clinical trial.
(2) After incubation of cells in a fresh medium (in the course of 18, 24 hours) there occurs a total restoration of the ultrastructure of the nuclei, granular endoplasmatic reticulum, mitochondria, due to the repairing and strong intensification of synthetic processes, respiration and glycolysis, mitotic activity of the cells.
(3) An important observation was that there was no patient disease free at 1 year in the group that did not receive intensification whereas there were patients who were free of disease up to 271 weeks in the group receiving late intensification.
(4) The first stage is characterized by circular disturbances of conditioned activity, vegetative shifts of compensatory character and intensification of individual characteristics of behaviour.
(5) Monospecific antisera against catalase and three enzymes of peroxisomal lipid beta-oxidation (acyl-CoA oxidase, bifunctional protein (enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase) and 3-ketoacyl-CoA thiolase) were used in conjunction with either the indirect immunoperoxidase method or the protein A-gold technique followed by silver intensification.
(6) It is interpreted to contribute to development or intensification of a caudal thoracic oesophageal sphincter.
(7) Some factors which suppress pigmentation are characterized: these are an increase in SH groups content, deficiency of tyrosine, rise in growth rate and reduction of the diameter of hairs, intensification of antagonism between melanocytes and keratinocytes.
(8) Postremission therapy consolidation has been judged to be necessary while the clinical roles of maintenance and intensification remain to be clarified and appear to still require an investigational approach.
(9) The extent of intensification varied both with mouse strain and treatment, indicating possible differences in repair capacity and LET-dependency of sensitization effects.
(10) Rats trained to the high-altitude hypoxia displayed signs of intensification of both the plastic and lytic processes; one of these processes prevailed in different cells.
(11) The cholinergic cells and processes within the pontomedullary reticular formation were studied in the rat by application of peroxidase-antiperoxidase immunohistochemistry with silver intensification for choline-acetyltransferase (ChAT).
(12) Intensification of surgical work on the basis of the standardization of the main stages of the patient's treatment is regarded as one of the approaches to the lethality reduction.
(13) In an intensification of his engagement with the EU debate, David Cameron, the UK prime minister, will take on the arguments for this semi-detached relationship with the EU during a visit to Iceland on Wednesday.
(14) Strategies to support chemotherapy dose intensification include BMT, use of CSFs and antiemetic drug combinations.
(15) In the case of agriculture, growing demand for food also requires sustainable intensification – in other words, producing more on less land, without unacceptable uses of chemicals and water to do so.
(16) In an intensification of Labour's attack on the justice and security bill, which will restrict access to some sensitive intelligence, the shadow justice secretary Sadiq Khan accuses Clarke of misrepresenting it.
(17) Among the 21 patients who received intensification, nine remain alive in a CR with a median survival of 27 months.
(18) These changes show the intensification on their specific function manifest in an increase of relative volume of intracellular structures.
(19) This was not microcredit's intended poverty reduction so much as the intensification of poverty , suffering and deprivation among the very poorest communities forced into informal sector work.
(20) The response from the SPD opposition was harsh and noted that the government's gradual approach had led to a dramatic intensification of the sovereign debt crisis.