(a.) At the utmost point, edge, or border; outermost; utmost; farthest; most remote; at the widest limit.
(a.) Last; final; conclusive; -- said of time; as, the extreme hour of life.
(a.) The best of worst; most urgent; greatest; highest; immoderate; excessive; most violent; as, an extreme case; extreme folly.
(a.) Radical; ultra; as, extreme opinions.
(a.) Extended or contracted as much as possible; -- said of intervals; as, an extreme sharp second; an extreme flat forth.
(n.) The utmost point or verge; that part which terminates a body; extremity.
(n.) Utmost limit or degree that is supposable or tolerable; hence, furthest degree; any undue departure from the mean; -- often in the plural: things at an extreme distance from each other, the most widely different states, etc.; as, extremes of heat and cold, of virtue and vice; extremes meet.
(n.) An extreme state or condition; hence, calamity, danger, distress, etc.
(n.) Either of the extreme terms of a syllogism, the middle term being interposed between them.
(n.) The first or the last term of a proportion or series.
Example Sentences:
(1) In this study of ten consecutive patients sustaining molten metal injuries to the lower extremity who were treated with excision and grafting, treatment with compression Unna paste boot was compared with that with conventional dressing.
(2) But Lee is mostly just extremely fed up at the exclusion of sex workers’ voices from much of the conversation.
(3) The extreme quenching of the dioxetane chemiluminescence by both microsomes and phosphatidylcholine, as a model phospholipid, implies that despite the low quantum yield (approx.
(4) The results show that endolymph is extremely inhomogenous with respect to calcium potentials.
(5) Even so, amputation of fifteen extremities and four other major excisions were required in twelve patients.
(6) I hope this movement will continue and spread for it has within itself the power to stand up to fascism, be victorious in the face of extremism and say no to oppressive political powers everywhere.” Appearing via videolink from Tehran, and joined by London mayor Sadiq Khan and Palme d’Or winner Mike Leigh, Farhadi said: “We are all citizens of the world and I will endeavour to protect and spread this unity.” The London screening of The Salesman on Sunday evening wasintended to be a show of unity and strength against Trump’s travel ban, which attempted to block arrivals in the US from seven predominantly Muslim countries: Iran, Iraq, Libya, Sudan, Somalia, Syria and Yemen.
(7) He had been extremely frustrated that indicators of economic recovery over the past few days had been drowned out by the clamour over the Labour leadership.
(8) Poor lipophilicity and extremely low plasma concentrations impose severe constraints.
(9) This suggests that molars do not maintain a fixed relationship to incisors over time, and extreme care must be taken to standardize an experiment to a specific body weight when using this method.
(10) Eighty-four paraplegic patients whose injury level was T2 or below and who were at least one year from spinal cord injury were screened for upper extremity complaints.
(11) A retrospective review was undertaken of 127 lower extremity fasciotomies performed for compartment syndrome after acute ischemia and revascularization in 73 patients with vascular trauma and 49 patients with arterial occlusive disease.
(12) TNBS reacts to an extremely small extend with hemoglobin over the concentration range 0.4 to 4 mM whereas FDNB reacts with hemoglobin to a very large extent (50 fold more than TNBS).
(13) While the reduced form of the "derived" polyphenolic compounds, generated during tissue homogenization, appeared to enhance dye binding with bovine serum albumin, their influence on the protein assay directly in crude homogenates was extremely diverse.
(14) Although statistical analysis did not show dramatic changes in all these parameters, some individual extreme values were substantially altered.
(15) Survival and healing of "extremely severe" grade intoxication can only be obtained through a surgical intervention within the first hours; a laparotomy will indicate the depth of the lesions, which is not determined by endoscopy, and will consist of Celerier's stripping method and if necessary a gastrectomy, more seldom a cephalic duodeno-pancreatectomy.
(16) In the absence of haemodialysis, the decline in plasma concentrations of lisinopril and enalaprilat was extremely slow and plasma concentrations were generally high.
(17) The authors recently observed 2 elderly female patients with ischemic pain of the upper extremity as the first manifestation of giant cell arteritis.
(18) In the process, the DfE's definition of extremism has shifted from actual bomb-throwers to religious conservatives.
(19) Accordingly, LPA proved an extremely stable characteristic which did not show any substantial variations in the course of five years.
(20) Formation of the functional contour plaster bandage within the limits of the foot along the border of the fissure of the ankle joint with preservation of the contours of the ankles 4-8 weeks after the treatment was started in accordance with the severity of the fractures of the ankles in 95 patients both without (6) and with (89) dislocation of the bone fragments allowed to achieve the bone consolidation of the ankle fragments with recovery of the supportive ability of the extremity in 85 (89.5%) of the patients, after 6-8 weeks (7.2%) in the patients without displacement and after 10-13 weeks (11.3%) with displacement of the bone fragments of the ankles.
Tough
Definition:
(superl.) Having the quality of flexibility without brittleness; yielding to force without breaking; capable of resisting great strain; as, the ligaments of animals are remarkably tough.
(superl.) Not easily broken; able to endure hardship; firm; strong; as, tough sinews.
(superl.) Not easily separated; viscous; clammy; tenacious; as, tough phlegm.
(superl.) Stiff; rigid; not flexible; stubborn; as, a tough bow.
(superl.) Severe; violent; as, a tough storm.
Example Sentences:
(1) Photograph: Guardian The research also compiled data covered by a wider definition of tax haven, including onshore jurisdictions such as the US state of Delaware – accused by the Cayman islands of playing "faster and looser" even than offshore jurisdictions – and the Republic of Ireland, which has come under sustained pressure from other EU states to reform its own low-tax, light-tough, regulatory environment.
(2) Nick Robins, head of the Climate Change Centre at HSBC, said: "If you think about low-carbon energy only in terms of carbon, then things look tough [in terms of not using coal].
(3) A series of hierarchical multiple regressions revealed the effects of Surgency, Agreeableness, Conscientiousness, Emotional Stability, and Intellect on evoking upset in spouses through condescension (e.g., treating spouse as stupid or inferior), possessiveness (demanding too much time and attention), abuse (slapping spouse), unfaithfulness (having sex with others), inconsiderateness (leaving toilet seat up), moodiness (crying a lot), alcohol abuse (drinking too much alcohol), emotional constriction (hiding emotions to act tough), and self-centeredness (acting selfishly).
(4) A lfred Ekpenyong knows first hand how tough it can be to find a secure foothold in mainstream society after leaving prison.
(5) The texture of a food item can be distinguished in hardness, toughness, stickiness, juiciness and chewability.
(6) Even as the Obama administration moves to deal with some of Guantánamo's most notorious captives, it faces tough challenges to closing the facility.
(7) "It's a tough group but other groups are also tough.
(8) This allowed it to claim that it was becoming more professional, tough minded and responsible.
(9) The austerity programmes administered by western governments in the wake of the 2008 global financial crisis were, of course, intended as a remedy, a tough but necessary course of treatment to relieve the symptoms of debts and deficits and to cure recession.
(10) And he pleased the audience with an acknowledgement that social work is a tough job and social workers only human.
(11) Trade unions have sought to highlight the insecurity of workers who have been forced into self-employment in the tough jobs market of recent years.
(12) UK negotiatiors, though, fought back hard -- thus Cameron's fighting talk in his press conference ( see 12.46pm ) 12.49pm BST Open Europe tweets Cameron's tough talk on the rebate: Open Europe (@OpenEurope) Cameron: in Feb we reached a clear deal rebate would remain unchanged, since then some have tried to question this agreement June 28, 2013 Open Europe (@OpenEurope) Cameron: I defeated these attempts to change the rebate, it will remain unchanged for this long term budget June 28, 2013 12.46pm BST David Cameron press conference underway In Brussels, David Cameron is holding his press conference now.
(13) The mechanical properties of compressed beam specimens of microcrystalline cellulose (Avicel pH 101) have been assessed in terms of the tensile strength (sigma t), Young's modulus (E) and the following fracture mechanics parameters: the critical stress intensity factor (KIC), the critical strain energy release rate (GIC) and the fracture toughness (R).
(14) "2013 was a tough year for us both in minerals and in oil and gas," Cochrane said, adding that the group had relied on"self help", including diversification which offset some of the challenges in its core mining market, improving operational efficiency, and strong growth in its after sales business, where orders were up 16% on 2012 and which accounted for 63% of revenues last year.
(15) "We carved out a few chances, but it was tough to break them down."
(16) Channel 5 will be hoping for a similar return for its new series, although with the launch audience around a third down on last year's opener, it may prove a tough ask.
(17) Dimon, the charismatic leader of the bank, had enjoyed a reputation as a tough, strict taskmaster, the kind of CEO every bank should have.
(18) Cameron put all of his betting chips on what seemed to be the party's trump card: the "vote for us, we're tough on migration and tough on migrants" strategy.
(19) As well as limited terms for MPs, Grillo has called for a referendum on the euro and a tough line on immigration.
(20) "It's a tough game but our best football has come in this competition and we'll try and show it next week.