(1) Either reagent dislocates FAD from the holoenzyme, leaving a characteristic mercaptide derivative of the apoenzyme.
(2) After restrained least-squares refinement of the enzyme-substrate complex with the riboflavin omitted from the model, additional electron density appeared near the pyrophosphate, which indicated the presence of an ADPR molecule in the FAD binding site of PHBH.
(3) RR spectra of fatty acyl-CoA and its complexes are consistent with the previous hypothesis that visible spectral shifts observed during formation of acetoacetyl-CoA and crotonyl-CoA complexes of fatty acyl-CoA dehydrogenase result from charge-transfer interactions in which the ground state is essentially nonbonding as opposed to interactions in which complete electron transfer occurs to form FAD semiquinone.
(4) Her full name is Kitty White, and she has a family and lives in London (due to a Japanese fad for all things British in the mid-1970s).
(5) D-Amino acid oxidase purified from the yeast Rhodotorula gracilis is a flavoenzyme which does not require exogenous FAD for maximum activity.
(6) Flavin adenine dinucleotide (FAD) was covalently attached to an electron-conducting support, i.e., glassy carbon.
(7) Transient kinetic analysis for the interaction of MCAD-FAD with IACoA suggests that the formation of the enzyme-IACoA complex proceeds in two steps.
(8) Alignment of these sequences with that of squash defines domains of nitrate reductase that appear to bind its 3 prosthetic groups (molybdopterin, heme-iron, and FAD).
(9) With so many superfoods jostling for attention in the media and on supermarket shelves, it’s not always easy to separate the fad from the genuinely healthy.
(10) The depth of FAD incorporation into the enzyme molecule as calculated according to the outer sphere electron transfer theory is 6.1 A.
(11) The half-life of the solubilized oxidoreductase stored at 2-4 degrees C in the presence of 25% glycerol at pH 8.6 is approximately 30 h. The oxidoreductase contains a flavoprotein identifiable by its fluorescence spectrum for FAD which binds weakly to concanavalin A-Sepharose and elutes from gel sieving columns at a molecular weight range of approximately 51,000.
(12) Lifetime risk of dementia in early-onset FAD kindreds is consistent with an autosomal dominant inheritance model.
(13) Thus, ETF appears to contain one flavin (at least 90% FAD, by chromatographic and fluorescence characteristics) per 26,000 M-r, and therefore may be composed of two subunits with one flavin each.
(14) Microcoulometric titrations of NADH:nitrate reductase at 25 degrees C in Mops buffer, pH 7.0, showed that the native enzyme, containing functional FAD, haem and Mo, required addition of five electrons for complete reduction.
(15) An automated AutoAnalyzer method using 5:5'-dithiobis-2-nitrobenzoic acid is described for determining whole blood glutathione reductase (BGR) activity and for measuring in vitro activation of BGR with flavin adenine dinucleotide (FAD).
(16) The kinetic course of the reaction of methanol and deutero-methanol with FAD-dependent alcohol oxidase was investigated under single-turnover conditions [kred approximately equal to 15000 min-1 (1H3COH) and approximately equal to 4300 min-1 (2H3COH)] and multiple-turnover conditions [TNmax approximately equal to 6000 min-1 (1H3COH) and approximately equal to 3100 min-1 (2H3COH)].
(17) It had been shown that thyroxine regulates the conversion of riboflavin to riboflavin mononucleotide and flavin adenine dinucleotide (FAD) in laboratory animals.
(18) The value of P of the enzyme is dependent on its concentration, indicating that the degrees of dissociation of FAD in the monomer and dimer are different.
(19) We now provide evidence for a major early onset FAD locus on the long arm of chromosome 14 near the markers D14S43 and D14S53 (multipoint lod score z = 23.4) and suggest that the inheritance of FAD may be more complex than had initially been suspected.
(20) Thus, the low activity resulting from an inherited deficiency of FAD is decreased further.
Rad
Definition:
() imp. & p. p. of Read, Rede.
Example Sentences:
(1) The axons of A5, RPoOl and RaD neurons exhibit no lateral predominance in their spinal projections.
(2) This was treated with local radiation therapy consisting of 2700 rads administered in 15 fractions during a period of 28 days.
(3) Genetical analysis revealed that resistance to trimethoprim resulted from forward mutations at separate loci rather than back mutations of rad 6 or rad 18 alleles.
(4) Analysis was performed on all patients who received any amount of therapy (VSG) and on the Adequately Treated Group (ATG), who had received 5000 or more rads radiotherapy, two or more courses of chemotherapy, and had a minimum survival of 8 or more weeks (the interval that would have been required to have received either the radiotherapy or chemotherapy).
(5) Liability of retransplanted syngeneic skin grafts to rejection could be almost entirely abolished by their exposure to 300 rads irradiation before placement on the intermediate host.
(6) Fourteen patients entered the study and each received megavoltage therapy to give a mean dose of 4600 rad to the pituitary over 31 days.
(7) At the 200 rad level, the mouse with normal karyotype was compared with the T(1;13)70H translocation heterozygote and the Ts(1(13))7OH tertiary trisomic of normal appearance.
(8) Of these, the first 36 patients received single doses to the UHB, mid-body (MB), or LHB using doses of 600 rad to the UHB and 800 rad to MB and LHB.
(9) This treatment will be repeated until a total dose of 5000--6000 rad.
(10) The morphologic changes produced in the liver through irradiation at the rate of 1000 rad are characterized chiefly by a well expressed fatty dystrophia.
(11) The hypoxic fraction increased dramatically when these tumours invaded the subcutaneous tissues, or when tumours were implanted subcutaneously (TCD50 greater than 5,544 rad).
(12) In the membranes a phosphoprotein of 32 kDa belonging to the NADPH oxidase-cytochrome b-245 system (P. Bellavite et al., Free Rad.
(13) The radiation dose to the kidney (3.6 rad) and to the whole body (0.36 rad) was acceptable.
(14) The generation of cellular and supernatant IL 2R was: dependent on cellular activation, rapid, radioresistant (3000 rad), and inhibited by cycloheximide treatment.
(15) He was submitted to radiotherapy with linear acceleration (total dose of 4000 rads) and surgery, during which the tumor could not be completely removed due to its large size.
(16) Of mice treated with 500 rad, 44% were cured, as were 100% given 800 rad of treatment.
(17) External beam radiation was also given (6000 rads) to 16 patients for curative intent and (3000 rads) to 9 patients for palliative intent.
(18) In order to evaluate the usefulness of gamma-ray-irradiation to improve the tolerance to wear of the sockets, the worn surface of the 2.5 M rad gamma-ray-irradiated HDP sockets after total hip arthroplasty has been quantified by a newly-developed 3 dimensional (3-D) image analysis method in combination with scanning electron microscopy (SEM).
(19) 100 to 1600 rad doses did not produce adverse effects on these cells.
(20) Chromosome aberrations induced by 500 rads gamma ray irradiation (dicentrics, rings, and fragments) were observed at the ultrastructural level using the "whole mount" technique.