(1) Either reagent dislocates FAD from the holoenzyme, leaving a characteristic mercaptide derivative of the apoenzyme.
(2) After restrained least-squares refinement of the enzyme-substrate complex with the riboflavin omitted from the model, additional electron density appeared near the pyrophosphate, which indicated the presence of an ADPR molecule in the FAD binding site of PHBH.
(3) RR spectra of fatty acyl-CoA and its complexes are consistent with the previous hypothesis that visible spectral shifts observed during formation of acetoacetyl-CoA and crotonyl-CoA complexes of fatty acyl-CoA dehydrogenase result from charge-transfer interactions in which the ground state is essentially nonbonding as opposed to interactions in which complete electron transfer occurs to form FAD semiquinone.
(4) Her full name is Kitty White, and she has a family and lives in London (due to a Japanese fad for all things British in the mid-1970s).
(5) D-Amino acid oxidase purified from the yeast Rhodotorula gracilis is a flavoenzyme which does not require exogenous FAD for maximum activity.
(6) Flavin adenine dinucleotide (FAD) was covalently attached to an electron-conducting support, i.e., glassy carbon.
(7) Transient kinetic analysis for the interaction of MCAD-FAD with IACoA suggests that the formation of the enzyme-IACoA complex proceeds in two steps.
(8) Alignment of these sequences with that of squash defines domains of nitrate reductase that appear to bind its 3 prosthetic groups (molybdopterin, heme-iron, and FAD).
(9) With so many superfoods jostling for attention in the media and on supermarket shelves, it’s not always easy to separate the fad from the genuinely healthy.
(10) The depth of FAD incorporation into the enzyme molecule as calculated according to the outer sphere electron transfer theory is 6.1 A.
(11) The half-life of the solubilized oxidoreductase stored at 2-4 degrees C in the presence of 25% glycerol at pH 8.6 is approximately 30 h. The oxidoreductase contains a flavoprotein identifiable by its fluorescence spectrum for FAD which binds weakly to concanavalin A-Sepharose and elutes from gel sieving columns at a molecular weight range of approximately 51,000.
(12) Lifetime risk of dementia in early-onset FAD kindreds is consistent with an autosomal dominant inheritance model.
(13) Thus, ETF appears to contain one flavin (at least 90% FAD, by chromatographic and fluorescence characteristics) per 26,000 M-r, and therefore may be composed of two subunits with one flavin each.
(14) Microcoulometric titrations of NADH:nitrate reductase at 25 degrees C in Mops buffer, pH 7.0, showed that the native enzyme, containing functional FAD, haem and Mo, required addition of five electrons for complete reduction.
(15) An automated AutoAnalyzer method using 5:5'-dithiobis-2-nitrobenzoic acid is described for determining whole blood glutathione reductase (BGR) activity and for measuring in vitro activation of BGR with flavin adenine dinucleotide (FAD).
(16) The kinetic course of the reaction of methanol and deutero-methanol with FAD-dependent alcohol oxidase was investigated under single-turnover conditions [kred approximately equal to 15000 min-1 (1H3COH) and approximately equal to 4300 min-1 (2H3COH)] and multiple-turnover conditions [TNmax approximately equal to 6000 min-1 (1H3COH) and approximately equal to 3100 min-1 (2H3COH)].
(17) It had been shown that thyroxine regulates the conversion of riboflavin to riboflavin mononucleotide and flavin adenine dinucleotide (FAD) in laboratory animals.
(18) The value of P of the enzyme is dependent on its concentration, indicating that the degrees of dissociation of FAD in the monomer and dimer are different.
(19) We now provide evidence for a major early onset FAD locus on the long arm of chromosome 14 near the markers D14S43 and D14S53 (multipoint lod score z = 23.4) and suggest that the inheritance of FAD may be more complex than had initially been suspected.
(20) Thus, the low activity resulting from an inherited deficiency of FAD is decreased further.
(1) She loved us and we loved her.” “We would have loved to have had a little grandchild from her,” she says sadly.
(2) Wimbledon said the world No1 Williams had been suffering from a viral illness and it was a sad and bizarre end to the American’s tournament, not to mention a worrying sight, seeing her hardly able to play.
(3) Sadly, the bullet will not only kill off Greece’s future in Europe.
(4) Calum MacLean, Grangemouth Petrochemicals chairman, says, “This is a hugely sad day for everyone at Grangemouth.
(5) Sadly, the Jewish fanatic who assassinated Rabin in 1995 achieved his broader aim of derailing the peace train.
(6) It also devalues the courage of real whistleblowers who have used proper channels to hold our government accountable.” McCain added: “It is a sad, yet perhaps fitting commentary on President Obama’s failed national security policies that he would commute the sentence of an individual that endangered the lives of American troops, diplomats, and intelligence sources by leaking hundreds of thousands of sensitive government documents to WikiLeaks, a virulently anti-American organisation that was a tool of Russia’s recent interference in our elections.” WikiLeaks last year published emails hacked from the accounts of the Democratic National Committee and John Podesta, chairman of Hillary Clinton’s election campaign.
(7) I watched as she made the briefest eye contact with me on their way back, the flicker of hurt and sadness in her eyes reflecting mine, before the shutters came down.
(8) Only at 3 days did total plasma volume of SAD rats show a modest reduction of about 16% (P less than 0.05 vs. sham-operated plus unoperated controls).
(9) These sad numbers show that more Washington spending, threats of higher taxes on small businesses, and excessive government regulations don't create a healthy environment for job growth," Boehner said.
(10) Thirty-two nursing students were shown silent films in which 10 normal and 10 schizophrenic women described a happy, sad, and an angry personal experience.
(11) World Wildlife Fund Great Barrier Reef campaigner Richard Leck said it was a sad day for the reef and anyone who cared about its future.
(12) It is so sad, we don’t let her go out even if the weather is nice,” he says.
(13) During interviews, married couples experiencing infertility reported emotional reactions such as sadness, depression, anger, confusion, desperation, hurt, embarrassment, and humiliation.
(14) Half of the rats in each group had SAD surgery 1 week prior to study.
(15) There’s an overwhelming sadness among kids like that who have been kept there for a very long time.
(16) It is sadly slightly the territory we have inherited,” he said.
(17) In a statement the family said they were left "extremely sad and disappointed" by the verdicts: "We appreciate the work and effort over the years since events on Broadwater Farm that night in trying to bring people to justice.
(18) Moreover, no differences were found in abnormal lung function patients with and those without SAD in demographic, clinical, roentgenologic, and serologic features and results of pulmonary function tests.
(19) It is sad that the BBC chose to give Nick Griffin a platform.
(20) The only thing I'd say is that I know, from people who've told me firsthand, that sadly mixed marriages can be a bit conflicted on everyday issues.