(a.) Proceeding from, or appointed by, fate or destiny; necessary; inevitable.
(a.) Foreboding death or great disaster.
(a.) Causing death or destruction; deadly; mortal; destructive; calamitous; as, a fatal wound; a fatal disease; a fatal day; a fatal error.
Example Sentences:
(1) Our prospective study has defined a number of important variables in patients with clinical evidence of mast cell proliferation that can predict both the presence of SMCD and the likelihood of fatal disease.
(2) Cardiovascular disease event rates will be assessed through continuous community surveillance of fatal and nonfatal myocardial infarction and stroke.
(3) And, as elsewhere in this epidemic, those on the frontline paid the highest price: four of the seven fatalities were health workers, including Adadevoh.
(4) The four patients treated in our series recovered fully; the single fatal case constituted an unrecognized case of pneumococcal endocarditis.
(5) Because of these different direct and indirect actions, a sudden cessation of sinus node activity or sudden AV block may result in the diseased heart in a prolonged and even fatal cardiac standstill, especially if the tolerance to ischemia of other organs (notably the brain) is decreased.
(6) In spite of antimalaria treatment, with cortisone and then with immuno-depressants, the outcome was fatal with a picture of acute reticulosis and neurological disorders.
(7) Therefore, we examined the relationship between the usual number of drinks consumed per occasion and the incidence of fatal injuries in a cohort of US adults.
(8) The charges against Harrison were filed just after two white men were accused of fatally shooting three black people in Tulsa in what prosecutors said were racially motivated attacks.
(9) Recognition and prompt treatment of this potentially fatal dermatological crisis is stressed.
(10) When the results of the different studies are pooled, however, there is a significant difference between those patients with true infarction, and those in whom infarction was excluded, in terms of overall mortality (12% and 7%; P less than 0.0001) and the development of subsequent non-fatal infarction (11% and 6%; P less than 0.05) when the results are analysed for a period of follow-up of one year.
(11) A retrospective study of autopsy-verified fatal pulmonary embolism at a department of infectious diseases was carried out, covering a four-year period (1980-83).
(12) The major toxicity was neurologic, with 12 patients (41%) reporting at least one episode; four of which were graded as severe and two as fatal.
(13) The 2 patients, who had been transplanted in a replicative state (HBeAg positive) showed a fatal course of hepatitis in the graft.
(14) Asian macaques are susceptible to fatal simian AIDS from a type D retrovirus, indigenous in macaques, and from a lentivirus, simian immunodeficiency virus (SIV), which is indigenous to healthy African monkeys.
(15) And any Labour commitment on spending is fatally undermined by their deficit amnesia.” Davey widened the attack on the Tories, following a public row this week between Clegg and Theresa May over the “snooper’s charter”, by accusing his cabinet colleague Eric Pickles of coming close to abusing his powers by blocking new onshore developments against the wishes of some local councils.
(16) Advances in blood banking and the availability of platelet transfusions have markedly decreased the incidence of fatal haemorrhage.
(18) The notion of life-threatening dermatoses may seem to be a contradiction in terms, but in fact there are a number of serious dermatologic conditions that require prompt attention to prevent fatal consequences.
(19) Slager, 33, was a patrolman first class for the North Charleston police department when he fatally shot Scott, 50, following a struggle that led from a traffic stop when the officer noticed that one of Scott’s car tail lights was broken.
(20) The problem is basically one of differentiating a correctable metabolic disorder from a lesion that can be fatal unless surgically removed.
Lethal
Definition:
(n.) One of the higher alcohols of the paraffine series obtained from spermaceti as a white crystalline solid. It is so called because it occurs in the ethereal salt of lauric acid.
(a.) Deadly; mortal; fatal.
Example Sentences:
(1) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
(2) In more than 70 per cent of these, brain injury is the decisive lethal factor.
(3) One rat strain (TAS) is susceptible to the anticoagulant and lethal effects of warfarin and the other two strains are homozygous for warfarin resistance genes from either wild Welsh (HW) or Scottish (HS) rats.
(4) The results are consistent with our previous suggestion that lethality for virulent SFV infection results from a lethal threshold of damage to neurons in the CNS and that attenuating mutations may reduce neuronal damage below this threshold level.
(5) Osteogenesis imperfecta is the common term for a heterogeneous group of heritable disorders of connective tissue with lethal and nonlethal forms.
(6) It was recently demonstrated that MRL-lpr lymphoid cells transferred into lethally irradiated MRL- +mice unexpectedly failed to induce the early onset of lupus syndrome and massive lymphadenopathy of the donor, instead they caused a severe wasting syndrome resembling graft-vs-host (GvH) disease.
(7) The marine vibrio alone is a powerful stimulus to mucus secretion but lethal for the host.
(8) In-vivo data are limited primarily to dominant lethal studies in rats and some in-vivo alkaline elution results.
(9) None of these MAbs showed any virus-neutralizing activity in vitro; however, mice passively immunized with the purified MAbs were protected from lethal infection by the JHM strain of mouse hepatitis virus.
(10) A variation of a procedure for localized mutagenesis (Hong and Ames, 1971) was employed to generate conditional lethal mutants in phosphatidylserine decarboxylase.
(11) A highly significant correlation was observed between neutralization of indirect hemolysis and neutralization of lethal activity.
(12) A retrospective study was conducted into 136 patients who had received surgical treatment for perforated gastroduodenal ulcers, with the view to establishing postoperative lethality and morbidity (comparing simple suturing with definitive ulcer surgery).
(13) These measures excluded unfavourable lethal outcomes even in cases complicated by Gayet-Wernicke encephalopathy.
(14) Frequency and localization of spontaneous and induced by high temperature (37 degrees C) recessive lethal mutations in X-chromosome of females belonging to the 1(1) ts 403 strain defective in synthesis of heat-shock proteins (HSP) were studied.
(15) As a consequence of deformation from spherical-to-cylindrical shape in the microvasculature, demands for increased surface membrane area leads to increases in surface membrane tension above critical levels for rupture, and the cancer cells are rapidly and lethally damaged.
(16) In almost 80% of sudden cardiac deaths in ACMP foci of acute myocardial ischemia are found, that can lead to ventricular fibrillation with lethal outcome.
(17) Analysis of the literature data on the use of various therapeutic approaches to the treatment of febrile schizophrenia has shown that so far psychiatry does not possess such methods of treatment which could allow the complete prevention of lethal outcomes in this disease.
(18) Our previous results have shown that SC injection of DHEA resulted in upregulation of the specific host immune response resulting in protection against a lethal infection.
(19) Recently, this laboratory has demonstrated an enhanced susceptibility toward the development of ischemia-related lethal ventricular arrhythmias in the presence of therapeutic serum concentrations of digoxin in conscious dogs after myocardial infarction.
(20) The results are discussed in terms of possible conjugation-associated changes that, at high Hfr to F(-) ratios, lead to lethal zygosis.