(n.) A fixed decree by which the order of things is prescribed; the immutable law of the universe; inevitable necessity; the force by which all existence is determined and conditioned.
(n.) Appointed lot; allotted life; arranged or predetermined event; destiny; especially, the final lot; doom; ruin; death.
(n.) The element of chance in the affairs of life; the unforeseen and unestimated conitions considered as a force shaping events; fortune; esp., opposing circumstances against which it is useless to struggle; as, fate was, or the fates were, against him.
(n.) The three goddesses, Clotho, Lachesis, and Atropos, sometimes called the Destinies, or Parcaewho were supposed to determine the course of human life. They are represented, one as holding the distaff, a second as spinning, and the third as cutting off the thread.
Example Sentences:
(1) "The Samaras government has proved to be dangerous; it cannot continue handling the country's fate."
(2) The fate of the inhibited fungus is the subject of this report.
(3) The Notch locus in Drosophila encodes a transmembrane protein required for the determination of cell fate in ectodermal cells.
(4) It is the second fate that is overtaking the government's higher education reforms.
(5) The urban wasteland ecosystem contained in outdoor lysimeters employed as a model gives valuable information and has considerable value in predicting the ecological fate of industrial chemicals.
(6) In this article we present a synthesis of recent information concerning the fate of lactate in skeletal muscle.
(7) To a large extent, the failure has been a consequence of a cold war-style deadlock – Russia and Iran on one side, and the west and most of the Arab world on the other – over the fate of Bashar al-Assad , a negotiating gap kept open by force in the shape of massive Russian and Iranian military support to keep the Syrian regime in place.
(8) The report's authors warns that to limit their spending councils will have "an incentive to discourage low-income families from living in the area" and that raises the possibility that councils will – like the ill-fated poll tax of the early 1990s – be left to chase desperately poor people through the courts for small amounts of unpaid tax.
(9) The fate of the same viruses was investigated also in non-stimulated separated lymphocytes for comparative purposes.
(10) He had been moved from a civilian prison to the country's intelligence HQ, leading Mansfield to question whether there was a disagreement among Syrian authorities about the fate of Khan.
(11) This finding is in apparent contrast to the fate of the endogenous Fc receptors expressed on mouse macrophages.
(12) It is also clear that apoptosis, which represents an alternative tissue injury-limiting fate to necrosis in situ, may be important in limiting tissue injury and determining whether inflammation persists or resolves.
(13) It's not a great stretch to see parallels between the movie's set-up and the film industry in 2012: disposable teens are manipulated into behaving in certain ways, before being degraded and dispatched, all the while being remotely observed by middle-aged men, gambling on their fates.
(14) The chapters deal with general preliminaries and indications for surgery, the selection of bypass material, surgical instruments for coronary opertaions, the methods of extracorporeal circulation, the distal coronary anastomosis, the proximal aortal anastomosis, intraoperative monitoring of results, intra- and postoperative myocardinal infarction, the fate of venous bypass grafts, operative treatment of the ruptured ventricular septum and papillary muscle, and ventricular aneurysmectomy.
(15) The comforts of home will determine Liverpool's fate in 2014, according to Brendan Rodgers, and they made a convincing start against Hull City.
(16) Back to my favourite Tunisian poet: “If, one day, a people desire to live, then fate will answer their call.
(17) When the EGF receptor on cultured 3T3 cells is affinity labeled with high specific activity 125I-EGF, and the fate of the affinity labeled EGF-receptor complex determined, the loss in binding activity was accounted for by receptor internalization and subsequent proteolytic processing of the EGF receptor molecules in the lysosomes.
(18) The fate of cholesteryl esters in high density lipoprotein (HDL) was studied to determine whether the transfer of esterified cholesterol from HDL to other plasma lipoproteins occurred to a significant extent in man.
(19) If Thatcher's government is in part to blame, then Bill Clinton's is even more so; driven by a desire to let every American own their own home, it was Clinton's decision to create the ill-fated sub-prime mortgage system .
(20) Su(H) is also involved in controlling the fates of sensillum accessory cells and is specifically expressed in two of these cells.
Predetermine
Definition:
(v. t.) To determine (something) beforehand.
(v. t.) To doom by previous decree; to foredoom.
(v. i.) To determine beforehand.
Example Sentences:
(1) When subjects centered themselves actively, or additionally, contracted trunk flexor or extensor muscles to predetermined levels of activity, no increase in trunk positioning accuracy was found.
(2) Employed method of observation gave quantitative information about the influence of odours on ratios of basic predeterminate activities, insect distribution pattern and their tendency to choose zones with an odour.
(3) The duration of electrophoresis was based on the migration of a marker dye for a predetermined distance.
(4) Ventricular fibrillation was then induced and, after predetermined downtimes ranging from 5 to 60 minutes, thoracotomy was performed, and open-chest bimanual cardiac massage was started.
(5) Anesthetized, intubated kittens were subjected to one of two procedures: (1) insertion of a suction catheter to a predetermined distance and withdrawal with or without the application of suction or (2) insertion of the catheter until resistance was met and withdrawal with or without the application of suction.
(6) Minute ventilation (VE) was kept constant at a predetermined individual level during all treatments.
(7) Thus, it appears that the increased expression of the regulatory MLC2 gene in SHR atrial cells is a predetermined event, which, most likely, participates in functional adaptation of the myocardium in response to pressure overload and subsequent hypertrophy.
(8) Furthermore, the minimal actual treatment differences that can be detected with a reasonable (80%) probability at a predetermined (5%) significance level using a crossover design were estimated for different electrophysiologic variables.
(9) Each student conducted a medication-history interview with one of two simulated patients who presented a predetermined history; interviews were videotaped from behind a one-way mirror.
(10) The %s of fibroblasts, PMN's lymphocytes, plasma cells and macrophages were estimated in a predetermined standardized area close to the apical termination of the junctional epithelium.
(11) Under in vitro inhibition of alpha-glucosidasic activity by glucose in hemolymph of Bee prenymphas, the reaction order (n) (predetermined according to the initial natural glycemia) decreases with increasing inhibitor concentration and the affinity constant between enzyme and substrate undergoes lower variations than in other cases where (n) does not change.
(12) The effect of indomethacin administration on the mortality rate of brain-injured rats was studied in four groups of animals subjected to a level of injury with a fluid-percussion apparatus predetermined to cause 50% mortality (50% lethal dose, or LD50).
(13) To estimate the mean cardiac output, at least two measurements should be made at predetermined points of the ventilatory cycle.
(14) Microliter volumes of cell suspension were placed directly onto a computer-controlled cryostage and cooled to a predetermined subzero temperature.
(15) A genetic procedure is directed for the isolation of chromosomal deletions and duplications with predetermined endpoints.
(16) Specific checklists completed by patients and predetermined scoring protocols yielded reliable data and reduced faculty time.
(17) "It seems that the Metropolitan police, the CPS [Crown Prosecution Service] and even the court have all colluded to implement a predetermined decision which was made in Washington.
(18) Various techniques can be used to deposit the dose accurately in a predetermined intracranial volume.
(19) The same brush was then agitated in a SBW vial, which was centrifuged, the cell pellet being smeared over a predetermined area of a slide.
(20) Eleven children with severe perennial asthma and a poor clinical response to disodium cromoglycate were studied in a 4-month, double blind trial involving 1 month's treatment with placebo, disodium cromoglycate, betamethasone 17 valerate, and both drugs combined according to a predetermined random design.