(n.) A perennial plant (Pyrethrum, / Chrysanthemum, Parthenium) allied to camomile, having finely divided leaves and white blossoms; -- so named from its supposed febrifugal qualities.
Example Sentences:
(1) A bioassay based on inhibition of the secretory activity of blood platelets by extracts of feverfew in comparison with parthenolide was also used.
(2) Extracts of the herb feverfew inhibit human blood platelet aggregation and secretion induced by a number of agents in-vitro and this may relate to the beneficial effects of feverfew in migraine.
(3) The results indicate that feverfew may have a vasoprotective effect in addition to its effects on platelets.
(4) Seventeen patients who ate fresh leaves of feverfew daily as prophylaxis against migraine participated in a double blind placebo controlled trial of the herb: eight patients received capsules containing freeze dried feverfew powder and nine placebo.
(5) Patch tests were negative for another 30 plants, including cocklebur (Xanthium strumarium), dog fennel (Anthemis cotula, fleabane (Erigeron strigosus), sneezeweed (Helenium autumnale), and feverfew (Tanacetum parthenium).
(6) The precise nature of the sulphydryl groups that are susceptible to feverfew and are involved in platelet aggregation and the release reaction have not yet been defined.
(7) Extracts of feverfew (Tanacetum parthenium) inhibited secretory activity in blood platelets and polymorphonuclear leucocytes (PMNs).
(8) Feverfew itself did not induce the formation of disulphide-linked protein polymers in platelets but polymer formation occurred when aggregating agents were added to feverfew-treated platelets.
(9) Three physicochemical methods (HPLC, NMR spectroscopy, and HPLC of a derivative) have been used to measure parthenolide in authenticated Tanacetum parthenium (feverfew) and in several commercial purported feverfew products.
(10) They also modify the interaction of platelets with collagen substrates: feverfew extracts inhibit both platelet spreading and formation of thrombus-like platelet aggregates on the collagen surface.
(11) Crude chloroform extracts of fresh feverfew leaves (rich in sesquiterpene lactones) and of commercially available powdered leaves (lactone-free) produced dose-dependent inhibition of the generation of thromboxane B2 (TXB2) and leukotriene B4 (LTB4) by ionophore- and chemoattractant-stimulated rat peritoneal leukocytes and human polymorphonuclear leukocytes.
(12) It is a simple, inexpensive, and reproducible high-throughput bioassay suitable for quality control of feverfew, Tanacetum parthenium, a crude drug with proven migraine prophylactic activity that is being considered for governmental registration and regulation.
(13) Inhibition of anti-IgE-induced histamine release by feverfew extract was observed when the drug was added simultaneously with anti-IgE and the inhibitory activity increased only slightly when the drug was preincubated with the cells for 5 min before anti-IgE stimulation.
(14) It was shown that feverfew extract (FE) inhibited the deposition of [51Cr]-labelled platelets on both CIII and CIV in a dose-dependent way.
(15) Positive patch test reactions were 2+ for dandelion (Taraxacum officinale), false ragweed (Ambrosia acanthicarpa), giant ragweed (Ambrosia trifida), short ragweed (Ambrosia artemisifolia), sagebrush (Artemisia tridentata), wild feverfew (Parthenium hysterophorus), yarrow (Achillea millifolium), and tansy (Tanacetum vulgare) and 1+ for Dahlia species and English ivy (Hedera helix).
(16) In this respect feverfew differs from cromoglycate and quercetin.
(17) There was a highly significant variance between the frequencies of SCE in the matched pairs of migraine patients but this was not related to age, sex or feverfew exposure.
(18) Parthenolide appears to be mainly responsible for the antisecretory effects of extracts of feverfew.
(19) The pharmacological properties of feverfew may thus be due to cytotoxicity, although the time course of the events described in this paper is different from those where feverfew appears to have more specific inhibitory effects.
(20) Two elderly individuals suffering from acute recurrent dermatitis of light-exposed skin between spring and autumn were shown to be allergic to feverfew (Tanacetum parthenium) of the Compositae family.
Perennial
Definition:
(a.) ing or continuing through the year; as, perennial fountains.
(a.) Continuing without cessation or intermission; perpetual; unceasing; never failing.
(a.) Continuing more than two years; as, a perennial steam, or root, or plant.
(n.) A perennial plant; a plant which lives or continues more than two years, whether it retains its leaves in winter or not.
Example Sentences:
(1) Eighty micrograms of the topically active parasympatholytic drug ipratropium were applied intranasally four times daily in 20 adults with perennial rhinitis and severe watery rhinorrhoea in a double-blind controlled cross-over trial.
(2) consider the X-ray findings verified in 3 groups of subjects: with Hayfiber, with perennial rhinitis and the last one being a control group.
(3) Eleven children with severe perennial asthma and a poor clinical response to disodium cromoglycate were studied in a 4-month, double blind trial involving 1 month's treatment with placebo, disodium cromoglycate, betamethasone 17 valerate, and both drugs combined according to a predetermined random design.
(4) Cruden Farm, Victoria The 54-hectare Murdoch family estate in Langwarrin south of Melbourne, Australia, features magnificent gardens complete with ponds, lemon-scented gum trees and two walled gardens and perennial borders.
(5) In this study, the authors evaluate the inhalant substances of the house, emphasizing the importance of Dermatophagoides pteronyssinus to cause perennial allergic rhinitis.
(6) A panel of human CD4+ T cell clones specific for the house dust mite was isolated from an atopic individual with perennial rhinitis.
(7) Patients who had both perennial symptoms and summer seasonal exacerbations had a higher incidence of a positive family history of atopy and developed symptoms earlier in life than those patients who had summer seasonal or perennial symptoms only.
(8) Patients with perennial rhinitis had a more vigorous response than the controls.
(9) The immediate changes in regional ventilation and pulmonary blood flow were studied in seventeen adults with perennial asthma and in two control persons, who were challenged by histamine inhalation (histamine induced asthma (HIA)).
(10) Twenty-eight patients with allergic perennial rhinitis treated for 2 years with parenteral semidepot immunotherapy were divided into two groups of 14 patients: group A receiving conventional aerosol nebulization (TNE), and group B, which received TNAI using a type F aerosol electrocompressor.
(11) We have something to say and something to offer on perennial political dilemmas.
(12) Specificity was 87% for pollens and 90% for perennial antigens.
(13) Overnight, Russia has moved from perennial rival to trusted friend, while Nato’s future is in peril.
(14) More males than females had summer seasonal symptoms whereas more females than males had perennial symptoms.
(15) The old-fashioned dining room, unpretentious atmosphere, and the three-course menus under €30 make it a perennial favourite.
(16) But Howitt says that while it is a problem that so much farmland has shifted from more adjustable crops to perennials like almonds, he has a simpler solution: better management of groundwater.
(17) They are the identification of factors causing severe disease as opposed to heavy infection; the effects of seasonal as opposed to perennial transmission; and the importance of transplacental transmission of microfilariae or soluble antigens.
(18) Together with his late wife Janet, he wrote 37 titles including perennial favourites The Jolly Postman and Burglar Bill, and by himself he is the author of many more, including The Pencil, and Woof!
(19) It seems that perennial rhinitis probably arises from abundance of domestic antigens more than for the other allergic manifestations, as the nose is the first filter to receive foreign particles.
(20) However, PAC differed from SAC in several respects: a history of exacerbation on exposure to house dust (PAC 42 per cent; SAC none) and an association with perennial rhinitis (PAC 75 per cent; SAC 12 per cent) were more common in PAC.