(adv.) At the end or conclusion; ultimately; lastly; as, the contest was long, but the Romans finally conquered.
(adv.) Completely; beyond recovery.
Example Sentences:
(1) Yet the Tory promise of fiscal rectitude prevailed in England Alexander had been in charge of Labour’s election strategy, but he could not strategise a victory over a 20-year-old Scottish nationalist who has not yet taken her finals.
(2) The oral nerve endings of the palate, the buccal mucosa and the periodontal ligament of the cat canine were characterized by the presence of a cellular envelope which is the final form of the Henle sheath.
(3) A progressively more precise approach to identifying affected individuals involves measuring body weight and height, then energy intake (or expenditure) and finally the basal metabolic rate (BMR).
(4) The final number of fibers--140,000-165,000--is reached by the sixth week after birth.
(5) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(6) Finally the advanced automation of the equipment allowed weekly the evaluation of catecholamines and the whole range of their known metabolites in 36 urine samples.
(7) Phenotypic relationships were examined between final score and 13 type appraisal traits and first lactation milk yield from 2935 Ayrshire, 3154 Brown Swiss, 13,110 Guernsey, 50,422 Jersey, and 924 Milking Shorthorn records.
(8) The stages of mourning involve cognitive learning of the reality of the loss; behaviours associated with mourning, such as searching, embody unlearning by extinction; finally, physiological concomitants of grief may influence unlearning by direct effects on neurotransmitters or neurohormones, such as cortisol, ACTH, or norepinephrine.
(9) The amino-terminal region of a 70 kDa mitochondrial outer membrane protein of yeast and the presequence of cytochrome c1, an inner membrane protein exposed to the intermembrane space, are thought to be responsible for localizing the proteins in their final destinations after synthesis in the cytosol.
(10) Certainly, Saunders did not land a single blow that threatened to stop his opponent, although he took quite a few himself that threatened his titles in the final few rounds.
(11) Finally, the automatized measurement system cuts the time spent by a factor of more than five.
(12) Finally, it could be observed that elevated osmotic pressures reduced the lysis of isolated secretory granules when bicarbonate ions were present in the incubation medium.
(13) Finally, 10 patients had an intra- and extrasellar tumour (group III).
(14) The automatic half of both the motor which advances the trepan as well as the second motor which rotates the trepan is triggered by the sudden change in electrical resistance between the trepan and the patient's internal body fluid, at the final stage of penetration.
(15) After immunoadsorbent purification, the final step in a purification procedure similar to that adopted for colon cancer CEA, two main molecular species were identified: 1) Material identical with colon cancer CEA with respect to molecular size, PCA solubility, ability to bind to Con A, and most important the ability to bind to specific monkey anti-CEA serum.
(16) Achilles tendon overuse injuries exist as a spectrum of diseases ranging from inflammation of the paratendinous tissue (paratenonitis), to structural degeneration of the tendon (tendinosis), and finally tendon rupture.
(17) They insist this is the best way of ensuring the country does not descend into chaos before the final withdrawal of combat troops.
(18) GlaxoSmithKline was unusually critical of the decision by Nice, the National Institute for Health and Clinical Excellence, and also the Scottish Medicines Consortium, to reject its drug belimumab (brand name Benlysta) in final draft guidance.
(19) Symptoms consistent with major affective disorder were present in one half and depressive spectrum diagnoses were made in one fourth of the cases prior to final diagnosis.
(20) Children are about to start their final term before exams.
Least
Definition:
(a.) Smallest, either in size or degree; shortest; lowest; most unimportant; as, the least insect; the least mercy; the least space.
(adv.) In the smallest or lowest degree; in a degree below all others; as, to reward those who least deserve it.
(conj.) See Lest, conj.
Example Sentences:
(1) The most actively proliferating region of the excurrent duct system is zone 3 of the epididymis, whereas the least active region is the ductuli efferentes.
(2) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(3) Arachidic acid was without effect, while linoleic acid and linolenic acid were (on a concentration basis) at least 5-times less active than arachidonic acid.
(4) These results show that the pathogenic phenotypes of MCF viruses are dissociable from the thymotropic phenotype and depend, at least in part, upon the enhancer sequences.
(5) These organic compounds were found to be stable on the sorbent tubes for at least seven days.
(6) Because cystine in medium was converted rapidly to cysteine and cysteinyl-NAC in the presence of NAC and given that cysteine has a higher affinity for uptake by EC than cystine, we conclude that the enhanced uptake of radioactivity was in the form of cysteine and at least part of the stimulatory effect of NAC on EC glutathione was due to a formation of cysteine by a mixed disulfide reaction of NAC with cystine similar to that previously reported for Chinese hamster ovarian cells (R. D. Issels et al.
(7) The patients should have received treatment for at least seven days and they should not be "ill".
(8) Extensive studies during recent years have shown that the interaction between hormone and membrane-bound receptor can affect the receptor characteristics in at least two ways.
(9) This modulation results from repetitive, alternating bursts of excitatory and inhibitory postsynaptic potentials, which are caused at least in part by synaptic feedback to the command neurons from identified classes of neurons in the feeding network.
(10) But the wounding charge in 2010 has become Brown's creation of a structural hole in the budget, more serious than the cyclical hit which the recession made in tax receipts, at least 4% of GDP.
(11) For his lone, perilous journey that defied the US occupation authorities, Burchett was pilloried, not least by his embedded colleagues.
(12) In 22 cases (63%), retinal detachment was at least partially flattened in the area of the posterior pole of the eye.
(13) An experimental Anaplasma marginale infection was induced in a splenectomized mule deer (Odocoileus hemionus hemionus) which persisted subclinically at least 376 days as detected by subinoculation into susceptible cattle.
(14) The family comprises at least three variable (V) gene segments, three constant (C) gene segments, and three junction (J) gene segments.
(15) TR was classified as follows: severe (massive systolic opacification and persistence of the microbubbles in the IVC for at least 20 seconds); moderate (moderate systolic opacification lasting less than 20 seconds); mild (slight systolic opacification lasting less than 10 seconds); insignificant TR (sporadic appearance of the contrast medium into the IVC).
(16) In vivo studies were performed in five healthy subjects for at least 3 h after ingestion of radiolabeled meals.
(17) Ryzhkov added: "I believe they want to keep him in prison for another three or four years at least, so he is not released until well after the next presidential elections in 2012."
(18) Patients served as their individual control based on observations of at least 1 year before the study.
(19) The reproducibility of the killing-curve method suggests that at least two different concentrations should be used and that a decrease in viable counts below 2 log10 after 24 hours does not exclude a synergistic action.
(20) She was not aware that it was an assassination attempt by alleged foreign agents.” If at least one of the women thought the killing was part of an elaborate prank, it might explain the “LOL” message emblazoned in large letters one of the killers t-shirts.