(a.) Preceding all others of a series or kind; the ordinal of one; earliest; as, the first day of a month; the first year of a reign.
(a.) Foremost; in front of, or in advance of, all others.
(a.) Most eminent or exalted; most excellent; chief; highest; as, Demosthenes was the first orator of Greece.
(adv.) Before any other person or thing in time, space, rank, etc.; -- much used in composition with adjectives and participles.
(n.) The upper part of a duet, trio, etc., either vocal or instrumental; -- so called because it generally expresses the air, and has a preeminence in the combined effect.
Example Sentences:
(1) First results let us assume that clinically silent TIAs also (in analogy to clinically silent brain infarctions) could be detected and located.
(2) Here we report that sperm from psr males fertilizes eggs, but that the paternal chromosomes are subsequently condensed into a chromatin mass before the first mitotic division of the egg and do not participate in further divisions.
(3) However, when first trimester specimens were analyzed, the direct-product measurements were significantly larger than the corresponding 3H2O assay results.
(4) In Patient 2 they were at first paroxysmal and unformed, with more prolonged metamorphopsia; later there appeared to be palinoptic formed images, possibly postictal in nature.
(5) Van Persie's knee injury meant that Mata could work in tandem with the delightfully nimble Kagawa, starting for the first time since 22 January.
(6) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(7) The issue of the Schizophrenia Bulletin is devoted to articles representing this full range of conceptual and empirical work on first-episode psychosis.
(8) We conclude that first-transit and blood-pool techniques are equally accurate methods for determining EF when the time-activity method of analysis is employed.
(9) Oculomotor paresis with cyclic spasms is a rare syndrome, usually noticeable at birth or developing during the first year of life.
(10) In early 2000, during the first months of Vladimir Putin’s presidency, Babitsky was kidnapped by Russian forces and disappeared for many weeks.
(11) The Frenchman’s 65th-minute goal was a fifth for United and redemptive after he conceded the penalty from which CSKA Moscow took a first-half lead.
(12) The intrauterine mean active pressure (MAP) in the nulliparous group was 1.51 kPa (SD 0.45) in the first stage and 2.71 kPa (SD 0.77) in the second stage.
(13) For the first time it was organized on the basis of population.
(14) Immunocompetence was also evident when the cells from thymectomized donors were first incubated with thymus extract for 1 hr and subsequently tested for reactivity.
(15) gamma-Aminobutyric acid (GABA) and glutamate release from the treated side was higher than the control value during the first 2-3 h, a result indicating an important role of glial cells in the inactivation of released transmitter.
(16) The results of the evaluation confirm that most problems seen by first level medical personnel in developing countries are simple, repetitive, and treatable at home or by a paramedical worker with a few safe, essential drugs, thus avoiding unnecessary visits to a doctor.
(17) Complementarity determining regions (CDR) are conserved to different extents, with the first CDR region in all family members being among the most conserved segments of the molecule.
(18) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(19) The present findings indicate that the deafferented [or isolated] hypothalamus remains neuronally isolated from the environment if the operation is carried out later than the end of the first week of life.
(20) Amino acid sequence analysis showed that both peaks had identical N-terminal sequences through the first 28 residues.
Lose
Definition:
(v. t.) To part with unintentionally or unwillingly, as by accident, misfortune, negligence, penalty, forfeit, etc.; to be deprived of; as, to lose money from one's purse or pocket, or in business or gaming; to lose an arm or a leg by amputation; to lose men in battle.
(v. t.) To cease to have; to possess no longer; to suffer diminution of; as, to lose one's relish for anything; to lose one's health.
(v. t.) Not to employ; to employ ineffectually; to throw away; to waste; to squander; as, to lose a day; to lose the benefits of instruction.
(v. t.) To wander from; to miss, so as not to be able to and; to go astray from; as, to lose one's way.
(v. t.) To ruin; to destroy; as destroy; as, the ship was lost on the ledge.
(v. t.) To be deprived of the view of; to cease to see or know the whereabouts of; as, he lost his companion in the crowd.
(v. t.) To fail to obtain or enjoy; to fail to gain or win; hence, to fail to catch with the mind or senses; to miss; as, I lost a part of what he said.
(v. t.) To cause to part with; to deprive of.
(v. t.) To prevent from gaining or obtaining.
(v. i.) To suffer loss, disadvantage, or defeat; to be worse off, esp. as the result of any kind of contest.
Example Sentences:
(1) It is my desperate hope that we close out of town.” In the book, God publishes his own 'It Getteth Better' video and clarifies his original writings on homosexuality: I remember dictating these lines to Moses; and afterward looking up to find him staring at me in wide-eyed astonishment, and saying, "Thou do knowest that when the Israelites read this, they're going to lose their fucking shit, right?"
(2) In fact, you might read it as a signal … that the president might well lose on this,” she said.
(3) Shelter’s analysis of MoJ figures highlights high-risk hotspots across the country where families are particularly at risk of losing their homes, with households in Newham, east London, most exposed to the possibility of eviction or repossession, with one in every 36 homes threatened.
(4) The effects of brain injury can be catastrophic and long-term so the impact of more research would be vast, but affected numbers are too small so it loses out.
(5) Larvae from fresh water eggs, cultured in fresh water and 'normal' laboratory cultures reached 50% infectivity in 3-5 days, losing potential infectivity in 11-15 days post-hatching.
(6) He's called out for his lack of imagination in a stinging review by a leading food critic (Oliver Platt) and - after being introduced to Twitter by his tech-savvy son (Emjay Anthony) - accidentally starts a flame war that will lead to him losing his job.
(7) • young clownfish will lose their ability to "smell" the anemone species that they shelter in.
(8) c-WRT-7 cells were found to differentiate into macrophage-like cells and to lose their growth capacity both in vitro and in vivo after incubation with LPS.
(9) By using these larger catheters, the surgeon will not lose the option of using isosmotic preparations.
(10) Winning and losing were predicted to be more significant in determining cardiovascular responses for Type A's than for Type B's.
(11) "I have to say that I have been a Chelsea player since 2004 and I have never had six minutes in my favour when I was losing.
(12) He would still lose some of his original cash, but it would be less.
(13) Moreover, respondents indicating initially relatively high levels of emotional eating who reported a reduction in that level were found to lose significantly (p less than 0.01) more reported weight and to be significantly (p less than 0.05) more successful at approaching target weight over the period of the study than respondents who continued to report high levels of emotional eating.
(14) In addition, we have shown that long-lived, presumably non-senescent, strains do not arise by suppressor mutation, but lose senescence plasmid DNA by another mechanism.
(15) We find that the labelled cell has a myelinated axon, but that the axon loses its myelin within 50 microns of the soma and has not yet been traced further.
(16) Duraphat-treated samples submerged in water after the exposure lost only about 50% of the deposited fluoride, whereas samples treated with 2% NaF are known to lose all their fluoride under similar circumstances, a condition which may be related to the favorable clinical effect of Duraphat.
(17) In the midst of all the newspaper headlines and vigils you can sometimes lose sight of the man who was on death row.
(18) Last month Walsall council announced it would close 15 of its 16 libraries, and residents told the Guardian they stood to lose vital community spaces as well as reading resources.
(19) Rayburn, who was also told by his jobcentre he would lose his benefits if he did not work without pay, said he spent almost two months stacking and cleaning shelves and sometimes doing night shifts.
(20) A growing educated middle class is losing touch with apartheid history and seeking alternatives.