(a.) To lower the pitch of; to cause to sound less sharp; to let fall from the pitch.
(a.) To reduce to an even surface or one approaching evenness; to make flat; to level; to make plane.
(a.) To throw down; to bring to the ground; to prostrate; hence, to depress; to deject; to dispirit.
(a.) To make vapid or insipid; to render stale.
(v. i.) To become or grow flat, even, depressed dull, vapid, spiritless, or depressed below pitch.
Example Sentences:
(1) In 22 cases (63%), retinal detachment was at least partially flattened in the area of the posterior pole of the eye.
(2) Opsin becomes incorporated into the disk membrane by a process of membrane expansion and fusion to form the flattened disks of the outer segment.
(3) The cells are predominantly monopolar, tightly packed, and are flattened at the outer border of the ring.
(4) Six patients, two of whom developed sciatic neuropathy, demonstrated complete flattening of the SSEP.
(5) A radical rearrangement of the organism occurred gradually: initially oval in shape, the parasite became round, then elongated, flattened, and underwent cytokinesis.
(6) The changes included swelling, blunting, and flattening of epithelial foot processes, were accompanied by decreased stainability of glomerular anionic sites, and were largely reversed by subsequent perfusion with the polyanion heparin.
(7) In an effort to decrease the treatment time for this technique, the flattening filter has been removed from an AECL Therac-6 linear accelerator and the characteristics of the resulting beam have been measured.
(8) In the cis-trans axis of the Golgi apparatus the following compartments were observed: (a) On the cis face there was a continuous osmiophilic tubular network referred to as the cis element; (b) a cis compartment composed of 3 or 4 NADPase-positive saccules perforated with pores in register forming wells that contained small vesicles; (c) a trans compartment composed of 1 or 2 TPPAse-positive elements underlying the NADPase ones, followed by 1 or 2 CMPase-positive elements that showed a flattened saccular part continuous with a network of anastomotic tubules.
(9) The flattening of neutrophils occurred soon after settling, and was not followed by extension.
(10) The streets of Jiegu are now littered with concrete remnants of modern structures and the flattened mud and painted wood of traditional Tibetan buildings.
(11) The EWRGP group showed a mean flattening in corneal curvature of 0.11 and 0.15 mm in the flattest and steepest corneal meridians, respectively.
(12) The lining epithelium was a single layer of flattened or cuboidal endocervical cells.
(13) The first eigenvector, when represented by grey scale maps depicting a pair of eyes, reveals that, as average threshold increases, the visual field rises and flattens, like an umbrella that, initially closed, is simultaneously opened and thrust upwards.
(14) In older children, there were a low vertebral signal and disappearance of the disc-vertebra borders on T1-weighted images and a high vertebral signal with a decreased and flattened disc signal on T2-weighted images.
(15) Poorly-differentiated tissue produced a more haphazard out-growth of pleomorphic cells with few processes and flattened pseudopodia.
(16) In the past, ovarian cancer was more common in higher social classes, but sociocultural differences seem to have flattened off over recent decades.
(17) In the SEM three corresponding types were identified, a relatively smooth spherical type, a highly ruffled type and a fairly smooth flattened type.
(18) This change in shape varied from a slight flattening of the LV and IVS during diastole to total reversal of the normal direction of septal curvature such that the IVS became concave toward the RV and convex toward the LV.
(19) By phase-contrast microscopy of living cells and in more detail by scanning electron microscopy, the megakaryocytes showed a nonreversible adherence, an extensive formation of filopodia around the periphery like the rays of the sun, and a tendency toward flattening.
(20) The nerve bundles, encircled by basal lamina, were enclosed by a thin connective tissue layer and by flattened fibroblast-like cells.
Grade
Definition:
(n.) A step or degree in any series, rank, quality, order; relative position or standing; as, grades of military rank; crimes of every grade; grades of flour.
(n.) The rate of ascent or descent; gradient; deviation from a level surface to an inclined plane; -- usually stated as so many feet per mile, or as one foot rise or fall in so many of horizontal distance; as, a heavy grade; a grade of twenty feet per mile, or of 1 in 264.
(n.) A graded ascending, descending, or level portion of a road; a gradient.
(n.) The result of crossing a native stock with some better breed. If the crossbreed have more than three fourths of the better blood, it is called high grade.
(v. t.) To arrange in order, steps, or degrees, according to size, quality, rank, etc.
(v. t.) To reduce to a level, or to an evenly progressive ascent, as the line of a canal or road.
(v. t.) To cross with some better breed; to improve the blood of.
(n.) A harsh scraping or cutting; a grating.
Example Sentences:
(1) These included bringing in the A* grade, reducing the number of modules from six to four, and a greater attempt to assess the whole course at the end.
(2) An effective graft-surveillance protocol needs to be applicable to all patients; practical in terms of time, effort, and cost; reliable; and able to detect, grade, and assess progression of lesions.
(3) The cumulative incidence of grade II and III acute GVHD in the 'low dose' cyclosporin group was 42% compared to 51% in the 'standard dose' group (P = 0.60).
(4) In the fall of 1975, 1,915 children in grades K through eight began a school-based program of supervised weekly rinsing with 0.2 percent aqueous solution of sodium fluoride in an unfluoridated community in the Finger Lakes area of upstate New York.
(5) Although MR imaging can accurately show high-grade chondromalacia patellae, it is less accurate in the detection of low-grade disease.
(6) These two types of transfer functions are appropriate to explain the transition to anaerobic metabolism (anaerobic threshold), with a hyperbolic transfer characteristic representing a graded transition; and a sigmoid transfer characteristic representing an abrupt transition.
(7) High-grade and low-grade candidemia were defined as 25 colony-forming units or more per 10 ml and 10 colony-forming units or fewer per 10 ml of blood, respectively.
(8) In the present study, the expression of type IV collagen associated with the basal membrane (BM) was studied histochemically (indirect immunoperoxidase-antiperoxidase) in cervical human papillomavirus (HPV) lesions (diagnosed using in situ DNA hybridization) of different grades.
(9) Expression of AR was compared with that of ER and PR as well as with tumour grade and age.
(10) Results showed significantly higher cardiac output in infants with grade III shunting than in infants with grade 0 and grade I shunting.
(11) Biotin-avidin immunoperoxidase analysis for hCG was performed on all paraffin blocks containing carcinoma-in-situ, grade I, grade II, and grade III transitional cell carcinoma.
(12) Occasional vomits occur postoperatively in over half of patients but we are sceptical of the value of graded postoperative feeding regimens.
(13) A previous study, on grade IV astrocytomas, compared a combination of photons and fast neutron boost to photons only, both treatments being delivered following a concentrated irradiation schedule.
(14) The sensitivity of 75 non-CNS solid tumors to mismatched dsRNA was compared to the high-grade astrocytomas in the HTCA.
(15) This study concludes that grade is the greatest predictor of survival, with only 37% of grade 3 patients surviving at 5 years.
(16) The mean acne scores, derived from grading and counting lesions and comedones, fell from 63.3 to 6 in the Diane 50 and from 64.2 to 4.5 in the Triphasil group.
(17) The hypothesis that experimentally determined survival times of Treponema pallidum in stored donor blood could be related to the number of treponemes initially present in the treponeme-blood mixtures was investigated by inoculating rabbits with three graded doses of treponemes suspended in donor blood and stored at 4 degrees C for various periods of time.
(18) Contrary to expectations, low SES was not associated with greater levels of hyperglycemia or grades of retinopathy.
(19) The overall prevalence of protein energy malnutrition (PEM) was found to be 81.8%, while 31.8, 44.1, 5.7 and 0.2% of children had Grades I, II, III and IV PEM, respectively.
(20) Survival and healing of "extremely severe" grade intoxication can only be obtained through a surgical intervention within the first hours; a laparotomy will indicate the depth of the lesions, which is not determined by endoscopy, and will consist of Celerier's stripping method and if necessary a gastrectomy, more seldom a cephalic duodeno-pancreatectomy.