(a.) To lower the pitch of; to cause to sound less sharp; to let fall from the pitch.
(a.) To reduce to an even surface or one approaching evenness; to make flat; to level; to make plane.
(a.) To throw down; to bring to the ground; to prostrate; hence, to depress; to deject; to dispirit.
(a.) To make vapid or insipid; to render stale.
(v. i.) To become or grow flat, even, depressed dull, vapid, spiritless, or depressed below pitch.
Example Sentences:
(1) In 22 cases (63%), retinal detachment was at least partially flattened in the area of the posterior pole of the eye.
(2) Opsin becomes incorporated into the disk membrane by a process of membrane expansion and fusion to form the flattened disks of the outer segment.
(3) The cells are predominantly monopolar, tightly packed, and are flattened at the outer border of the ring.
(4) Six patients, two of whom developed sciatic neuropathy, demonstrated complete flattening of the SSEP.
(5) A radical rearrangement of the organism occurred gradually: initially oval in shape, the parasite became round, then elongated, flattened, and underwent cytokinesis.
(6) The changes included swelling, blunting, and flattening of epithelial foot processes, were accompanied by decreased stainability of glomerular anionic sites, and were largely reversed by subsequent perfusion with the polyanion heparin.
(7) In an effort to decrease the treatment time for this technique, the flattening filter has been removed from an AECL Therac-6 linear accelerator and the characteristics of the resulting beam have been measured.
(8) In the cis-trans axis of the Golgi apparatus the following compartments were observed: (a) On the cis face there was a continuous osmiophilic tubular network referred to as the cis element; (b) a cis compartment composed of 3 or 4 NADPase-positive saccules perforated with pores in register forming wells that contained small vesicles; (c) a trans compartment composed of 1 or 2 TPPAse-positive elements underlying the NADPase ones, followed by 1 or 2 CMPase-positive elements that showed a flattened saccular part continuous with a network of anastomotic tubules.
(9) The flattening of neutrophils occurred soon after settling, and was not followed by extension.
(10) The streets of Jiegu are now littered with concrete remnants of modern structures and the flattened mud and painted wood of traditional Tibetan buildings.
(11) The EWRGP group showed a mean flattening in corneal curvature of 0.11 and 0.15 mm in the flattest and steepest corneal meridians, respectively.
(12) The lining epithelium was a single layer of flattened or cuboidal endocervical cells.
(13) The first eigenvector, when represented by grey scale maps depicting a pair of eyes, reveals that, as average threshold increases, the visual field rises and flattens, like an umbrella that, initially closed, is simultaneously opened and thrust upwards.
(14) In older children, there were a low vertebral signal and disappearance of the disc-vertebra borders on T1-weighted images and a high vertebral signal with a decreased and flattened disc signal on T2-weighted images.
(15) Poorly-differentiated tissue produced a more haphazard out-growth of pleomorphic cells with few processes and flattened pseudopodia.
(16) In the past, ovarian cancer was more common in higher social classes, but sociocultural differences seem to have flattened off over recent decades.
(17) In the SEM three corresponding types were identified, a relatively smooth spherical type, a highly ruffled type and a fairly smooth flattened type.
(18) This change in shape varied from a slight flattening of the LV and IVS during diastole to total reversal of the normal direction of septal curvature such that the IVS became concave toward the RV and convex toward the LV.
(19) By phase-contrast microscopy of living cells and in more detail by scanning electron microscopy, the megakaryocytes showed a nonreversible adherence, an extensive formation of filopodia around the periphery like the rays of the sun, and a tendency toward flattening.
(20) The nerve bundles, encircled by basal lamina, were enclosed by a thin connective tissue layer and by flattened fibroblast-like cells.
Surface
Definition:
(n.) The exterior part of anything that has length and breadth; one of the limits that bound a solid, esp. the upper face; superficies; the outside; as, the surface of the earth; the surface of a diamond; the surface of the body.
(n.) Hence, outward or external appearance.
(n.) A magnitude that has length and breadth without thickness; superficies; as, a plane surface; a spherical surface.
(n.) That part of the side which is terminated by the flank prolonged, and the angle of the nearest bastion.
(v. t.) To give a surface to; especially, to cause to have a smooth or plain surface; to make smooth or plain.
(v. t.) To work over the surface or soil of, as ground, in hunting for gold.
Example Sentences:
(1) The resulting dose distribution is displayed using traditional 2-dimensional displays or as an isodose surface composited with underlying anatomy and the target volume.
(2) Phospholipid methylation in human EGMs is distinctly different from that in rat EGMs (Hirata and Axelrod 1980) in that the human activity is not Mg++-dependent, and apparent methyltransferase I activity is located in the external membrane surface.
(3) To quantify the size of the lesion in mice, the area of the infarct on the brain surface was assessed planimetrically 48 h after MCA occlusion by transcardial perfusion of carbon black.
(4) Using monoclonal antibodies directed against the plasma membrane of Madin-Darby canine kidney (MDCK) cells, we demonstrated previously that a glycoprotein with an Mr = 23,000 (gp23) had a non-polarized cell surface distribution and was observed on both the apical and basolateral membranes (Ojakian, G. K., Romain, R. E., and Herz, R. E. (1987) Am.
(5) In the surface epithelial cells, the basolateral cell surface showed moderate enzymatic activity.
(6) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(7) The role of Ca2+ in cell agglutination may be either to activate the cell-surface dextran receptor or to form specific intercellular Ca2+ bridges.
(8) The subcellular distribution of sialyltransferase and its product of action, sialic acid, was investigated in the undifferentiated cells of the rat intestinal crypts and compared with the pattern observed in the differentiated cells present in the surface epithelium.
(9) Even with hepatic lipase, phospholipid hydrolysis could not deplete VLDL and IDL of sufficient phospholipid molecules to account for the loss of surface phospholipid that accompanies triacylglycerol hydrolysis and decreasing core volume as LDL is formed (or for conversion of HDL2 to HDL3).
(10) A total of 555 caries lesions were registered on proximal surfaces, 49.1% being primary lesions in the enamel, 21.4% primary lesions into the dentin and 29.5% secondary lesions.
(11) Contact angles of Silafocon A and PMMA were relatively uninfluenced by front surface radii between 7.7 and 8.85 and 7.3 to 8.8 mm, respectively.
(12) These cells contained organelles characteristic of the maturation stage ameloblast and often extended to the enamel surface, suggesting a possible origin from the ameloblast layer.
(13) Together these observations suggest that cytotactin is an endogenous cell surface modulatory protein and provide a possible mechanism whereby cytotactin may contribute to pattern formation during development, regeneration, tumorigenesis, and wound healing.
(14) Our Ph1-positive ALL revealed B-cell lineage leukemia, since their surface phenotype were Ia+ and CD10+ and they have rearranged immunoglobulin JH genes.
(15) The complete nucleotide sequence of the gene for a cell surface protein antigen (SpaA) of Streptococcus sobrinus MT3791 (serotype g) was determined.
(16) To investigate the mechanism of enhanced responsiveness of cholesterol-enriched human platelets, we compared stimulation by surface-membrane-receptor (thrombin) and post-receptor (AlF4-) G-protein-directed pathways.
(17) Lysis of EAC4b,3b cellular intermediates formed to contain a low surface amount of C3b was more inhibited than was lysis of cells formed with a standard amount of C3b on the surface.
(18) After either 5 or 10 days of culture with both cytokines, intense immunofluorescent staining for Ia could be identified on the surface of greater than 80-90% of the viable islet cells.
(19) Within the capillary-perfused mucosa and muscularis (between 50 and 2000 microns from the urothelial surface), concentrations decreased by 50% for each 500-microns distance.
(20) Displacement of the surface of the cornea of bovine eyes after disruption of intact structures was investigated by means of holographic interferometry.