(1) The frequency of rare fragile sites was studied among 240 children in special schools for subnormal intelligence (IQ 52-85).
(2) A total of 13 ascertainments of folate sensitive autosomal fragile sites is observed, of which 10q23 fragility appears to be the most frequent.
(3) The fragile site at 10q25 was expressed in larger proportions of malignant than normal cells.
(4) The green fund contributions already announced (which include a $3bn pledge by the US and a $1.5bn pledge by Japan revealed during the G20 summit) “show very clearly that if we want the emerging countries and the more fragile countries to participate in this global growth, we have to ... support them,” Hollande said.
(5) Direct detection of the mutation enables the identification of fragile X negative normal transmitting males and fragile X negative carrier females.
(6) Tim Potter, managing director of support charity the Fragile X Society , adds that the challenges Tom faces in the film will give "hope and encouragement to many other families".
(7) A case of fragile-X syndrome (the Martin-Bell syndrome) in two male half-sibs from different marriages of their mother was described.
(8) Of the 188 males, 19 were found to have the fragile X syndrome, while the remaining 169 males had no recognizable cause of their mental retardation, including normal chromosomes.
(9) "The world economy remains in a deep recession and its financial system in a fragile condition," King said.
(10) A correlation between specific fragile sites and cancer breakpoints has been suggested raising the question of fragile site expression as a predisposing factor in the occurrence of cancer in some persons.
(11) Taking this into account, we derived equilibrium equations for the fragile X [fra(X)] genotype frequencies.
(12) An 18-year-old mentally retarded male with the Martin-Bell syndrome was fragile X positive.
(13) The problems Europe is having today could have a very real effect on our economy at a time when it's already fragile.
(14) The economics of the scene, she says, are "fragile".
(15) A significant relationship with heritable fragile sites was found in this study.
(16) It is associated with bony fragility, blue sclerae and abnormality of tooth dentin.
(17) The ankylosed spine may be fractured following relatively mild trauma attributable to loss of flexibility and increased fragility from osteoporosis.
(18) Apart from evidence of enhanced lysosomal and peroxisomal fragility, probably secondary to the intracellular oedema, the intracellular organelles investigated in this study were unaffected by the myopathic process.
(19) "The economy is still far too fragile to talk of a sustained recovery in the housing market, but the hope is that we are past the worst," he added.
(20) Of these new DNA markers, 5 lie in an interval defined as containing the fragile X region.
Frailty
Definition:
(a.) The condition quality of being frail, physically, mentally, or morally, frailness; infirmity; weakness of resolution; liableness to be deceived or seduced.
(a.) A fault proceeding from weakness; foible; sin of infirmity.
Example Sentences:
(1) As he told us: 'Individual faults and frailties are no excuse to give in and no exemption from the common obligation to give of ourselves.'
(2) The interplay of policies and principles to which Miss Nightingale subscribed, the human frailty of one of her women, Miss Nightingale's illness, and the confusion and stress which characterized the Crimean War are discussed.
(3) The demand for care at home is set to grow rapidly – changing patterns of disease and demography will see more us with long-term conditions and frailty in older age.
(4) Chelsea have not been defensively tight this term, their frailties masked by attacking prowess at the other end, but the sight of Draxler gliding through them at will was disturbing.
(5) That's a harsh form of exceptionalism in a culture of implicit contempt for the elderly's frailty, dependence and intense vulnerability.
(6) But the frailty of a three-minute song – the concise honesty of that expression – amazes me and turns me into a bucket of jealousy.
(7) Frailty is a state of reduced physiologic reserve associated with increased susceptibility to disability.
(8) To establish the concurrent validity of our new balance instrument, functional reach (FR = maximal safe standing forward reach), as a marker of physical frailty compared with other clinical measures of physical performance.
(9) Furthermore, the sickest or most vulnerable members of a clinical population may be least able to provide valid health status information because of dementia, frailty, blindness, illiteracy, or inability to speak English.
(10) What we have lost is any concept of honouring the elders, respect for their frailty, and recognition that supporting their final years before death is important for all of us – that death is a part of what makes all of our lives meaningful.
(11) Whatever the faults of the Australian media , by and large we have not sought to profit from the ruthless destruction of the famous or the powerful for the mere exercising of the human frailties which beset us all.” The Olle lecture is held by ABC 702 each year in memory of the late broadcaster Andrew Olle who died of a brain tumour in 1995.
(12) A trend of increasing peak plasma levels and bioavailability was observed with increasing age and frailty, with the differences more apparent between the active elderly and frail elderly groups than between the active elderly and young volunteers.
(13) Gross had become an indispensable friend of the publisher George Weidenfeld, who called him "a deeply civilised and compassionate observer of human frailty, a good-humoured sceptic who never forgets but almost always forgives".
(14) He has a year to run on his contract at Arsenal, where the team’s familiar frailties have generated some frustration within the fanbase.
(15) There is no shortage of people – psychologists, sociologists, doctors – looking beyond the frailties of the human mind for wider causes.
(16) As his muscles seized up, Twitter enlarged its bile duct to discharge ludicrous claims that this moment of physical frailty indicated mental weakness – as if an ill-timed injury somehow legitimised the irrational antipathy which many seem to feel towards the world’s best player, even in a country that is famously generous towards its brightest stars.
(17) He described how, during the trip back home in the taxi with his wife, he kept on crying.” Fred Ballinger, the composer he plays, loafs around a high-tone Swiss spa hotel with his old pal Mick, a veteran Hollywood film director played by Harvey Keitel , and casts a wearied eye over human frailties – both his own and those of people around him.
(18) Masri’s poetry vividly encapsulates the frailty of our human condition in a brutal society.
(19) Elderly patients with certain characteristics - especially physical frailty and severe cognitive impairement - comprise a high-risk subgroup for whom relocation is likely to be fatal.
(20) As far as your recollection goes, this was not disclosed to you by the MSC?” “With the frailty of memory, that’s right,” responded Kandiah.