(n.) The condition or quality of being fragile; brittleness; frangibility.
(n.) Weakness; feebleness.
(n.) Liability to error and sin; frailty.
Example Sentences:
(1) The frequency of rare fragile sites was studied among 240 children in special schools for subnormal intelligence (IQ 52-85).
(2) A total of 13 ascertainments of folate sensitive autosomal fragile sites is observed, of which 10q23 fragility appears to be the most frequent.
(3) The fragile site at 10q25 was expressed in larger proportions of malignant than normal cells.
(4) The green fund contributions already announced (which include a $3bn pledge by the US and a $1.5bn pledge by Japan revealed during the G20 summit) “show very clearly that if we want the emerging countries and the more fragile countries to participate in this global growth, we have to ... support them,” Hollande said.
(5) Direct detection of the mutation enables the identification of fragile X negative normal transmitting males and fragile X negative carrier females.
(6) Tim Potter, managing director of support charity the Fragile X Society , adds that the challenges Tom faces in the film will give "hope and encouragement to many other families".
(7) A case of fragile-X syndrome (the Martin-Bell syndrome) in two male half-sibs from different marriages of their mother was described.
(8) Of the 188 males, 19 were found to have the fragile X syndrome, while the remaining 169 males had no recognizable cause of their mental retardation, including normal chromosomes.
(9) "The world economy remains in a deep recession and its financial system in a fragile condition," King said.
(10) A correlation between specific fragile sites and cancer breakpoints has been suggested raising the question of fragile site expression as a predisposing factor in the occurrence of cancer in some persons.
(11) Taking this into account, we derived equilibrium equations for the fragile X [fra(X)] genotype frequencies.
(12) An 18-year-old mentally retarded male with the Martin-Bell syndrome was fragile X positive.
(13) The problems Europe is having today could have a very real effect on our economy at a time when it's already fragile.
(14) The economics of the scene, she says, are "fragile".
(15) A significant relationship with heritable fragile sites was found in this study.
(16) It is associated with bony fragility, blue sclerae and abnormality of tooth dentin.
(17) The ankylosed spine may be fractured following relatively mild trauma attributable to loss of flexibility and increased fragility from osteoporosis.
(18) Apart from evidence of enhanced lysosomal and peroxisomal fragility, probably secondary to the intracellular oedema, the intracellular organelles investigated in this study were unaffected by the myopathic process.
(19) "The economy is still far too fragile to talk of a sustained recovery in the housing market, but the hope is that we are past the worst," he added.
(20) Of these new DNA markers, 5 lie in an interval defined as containing the fragile X region.
Sin
Definition:
(adv., prep., & conj.) Old form of Since.
(n.) Transgression of the law of God; disobedience of the divine command; any violation of God's will, either in purpose or conduct; moral deficiency in the character; iniquity; as, sins of omission and sins of commission.
(n.) An offense, in general; a violation of propriety; a misdemeanor; as, a sin against good manners.
(n.) A sin offering; a sacrifice for sin.
(n.) An embodiment of sin; a very wicked person.
(n.) To depart voluntarily from the path of duty prescribed by God to man; to violate the divine law in any particular, by actual transgression or by the neglect or nonobservance of its injunctions; to violate any known rule of duty; -- often followed by against.
(n.) To violate human rights, law, or propriety; to commit an offense; to trespass; to transgress.
Example Sentences:
(1) Molsidomine and SIN-1 were tested in a thrombosis model in which thrombi are produced in small mesenteric vessels.
(2) These results support a hypothesis which proposes that ancestral SIN virus diverged into two distinct groups.
(3) Our studies show that SIN-1 and C87-3754 exert beneficial effects in a 6-h model of myocardial ischemia-reperfusion.
(4) Antibodies to all viruses were detected, and namely in these frequencies: SIN 0.9%, WN 16.9%, TAH 41.5%, CVO 23.1% and TBE 8.5%.
(5) As the later Spark might have said, a mortal sin against the commandment to love beauty wherever one may find it.
(6) The direct acting stimulants of soluble guanylate cyclase, sodium nitroprusside and SIN-1 (3-morpholino-sydnonimine), also increased the cGMP content of endothelial cells by 9.4 and 7.2 times, respectively.
(7) In superfused precontracted strips of rabbit aorta, methylene blue (MeB) or pyocyanin (Pyo, 1-hydroxy-5-methyl phenazinum betaine) at concentrations of 1-10 microM inhibited relaxations induced by endothelium-derived relaxing factor (EDRF), glyceryl trinitrate (GTN), S-nitroso-N-acetyl-penicillamine (SNAP) or 3-morpholino-sydnonimine (SIN-1).
(8) The likes of almond, blackberry and crocus first made way for analogue, block graph and celebrity in the Oxford Junior Dictionary in 2007, with protests at the time around the loss of a host of religious words such as bishop, saint and sin.
(9) These prostanoids were measured in platelets and endothelial cells alone or during their interaction, in the absence or presence of SIN-1.
(10) The haemodynamic effects of N-carboxy-3-morpholino-sydronimine-ethylester (molsidomine, SIN 10, Corvaton) were studied in anaesthetized mongrel dogs.
(11) The results indicated that both Sin B and Sal have inductive actions on drug metabolizing-phase I and phase II enzymes in mice and rats.
(12) Ten women with SIN were bilaterally salpingectomized.
(13) Analysis of the relationship between the pharmacodynamics and pharmacokinetics of SIN-1 suggests that an active metabolites is involved.
(14) The guanidine 3', 5'-cyclic monophosphate (cGMP) content (an index of EDRF production) was determined by radioimmunoassay under basal conditions and after acetylcholine (10(-5) M), bradykinin (10(-5) M) and SIN-1 (10(-4) M) stimulation.
(15) sin- mutants (defining six genes) were identified because they express HO in the absence of particular SWI products.
(16) We studied the effects of intracoronary injections of SIN-1 (0.8 mg), the active metabolite of molsidomine, on coronary artery diameters and coronary stenoses.
(17) Sessions included "naming the sin, lifting the shame" and "normal sinfulness or a sickness".
(18) The nitric oxide donor compound, 3-morpholinosydnonimine (SIN-1), was equipotent at relaxing the central and peripheral airways.
(19) Oxyhaemoglobin used for the assay of NO, inhibited the relaxation by SIN-1, but did not reduce vessel relaxations induced by GTN or iloprost, a stable prostacyclin analogue.
(20) A degraded SIN-1 solution that did not release NO was unable to block NMDA receptors.