(superl.) Exempt from subjection to the will of others; not under restraint, control, or compulsion; able to follow one's own impulses, desires, or inclinations; determining one's own course of action; not dependent; at liberty.
(superl.) Not under an arbitrary or despotic government; subject only to fixed laws regularly and fairly administered, and defended by them from encroachments upon natural or acquired rights; enjoying political liberty.
(superl.) Liberated, by arriving at a certain age, from the control of parents, guardian, or master.
(superl.) Not confined or imprisoned; released from arrest; liberated; at liberty to go.
(superl.) Not subjected to the laws of physical necessity; capable of voluntary activity; endowed with moral liberty; -- said of the will.
(superl.) Clear of offense or crime; guiltless; innocent.
(superl.) Unconstrained by timidity or distrust; unreserved; ingenuous; frank; familiar; communicative.
(superl.) Unrestrained; immoderate; lavish; licentious; -- used in a bad sense.
(superl.) Not close or parsimonious; liberal; open-handed; lavish; as, free with his money.
(superl.) Exempt; clear; released; liberated; not encumbered or troubled with; as, free from pain; free from a burden; -- followed by from, or, rarely, by of.
(superl.) Characteristic of one acting without restraint; charming; easy.
(superl.) Ready; eager; acting without spurring or whipping; spirited; as, a free horse.
(superl.) Invested with a particular freedom or franchise; enjoying certain immunities or privileges; admitted to special rights; -- followed by of.
(superl.) Thrown open, or made accessible, to all; to be enjoyed without limitations; unrestricted; not obstructed, engrossed, or appropriated; open; -- said of a thing to be possessed or enjoyed; as, a free school.
(superl.) Not gained by importunity or purchase; gratuitous; spontaneous; as, free admission; a free gift.
(superl.) Not arbitrary or despotic; assuring liberty; defending individual rights against encroachment by any person or class; instituted by a free people; -- said of a government, institutions, etc.
(superl.) Certain or honorable; the opposite of base; as, free service; free socage.
(superl.) Privileged or individual; the opposite of common; as, a free fishery; a free warren.
(superl.) Not united or combined with anything else; separated; dissevered; unattached; at liberty to escape; as, free carbonic acid gas; free cells.
(adv.) Freely; willingly.
(adv.) Without charge; as, children admitted free.
(a.) To make free; to set at liberty; to rid of that which confines, limits, embarrasses, oppresses, etc.; to release; to disengage; to clear; -- followed by from, and sometimes by off; as, to free a captive or a slave; to be freed of these inconveniences.
(a.) To remove, as something that confines or bars; to relieve from the constraint of.
(a.) To frank.
Example Sentences:
(1) Cancer patients showed abnormally high plasma free tryptophan levels.
(2) In conclusion, the efficacy of free tissue transfer in the treatment of osteomyelitis is geared mainly at enabling the surgeon to perform a wide radical debridement of infected and nonviable soft tissue and bone.
(3) The authors have presented in two previous articles the graphic solutions resembling Tscherning ellipses, for spherical as well as for aspherical ophthalmic lenses free of astigmatism or power error.
(4) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(5) With NaCl as the major constituent of the bathing solution (potassium-free pipette and external solutions) the reversal potential (Er) of the noradrenaline-evoked current was about 0 mV.
(6) In cardiac tissue the adenylate system is not a good indicator of the energy state of the mitochondrion, even when the concentrations of AMP and free cytosolic ADP are calculated from the adenylate kinase and creatine kinase equilibria.
(7) The promoters of the adenovirus 2 major late gene, the mouse beta-globin gene, the mouse immunoglobulin VH gene and the LTR of the human T-lymphotropic retrovirus type I were tested for their transcription activities in cell-free extracts of four cell lines; HeLa, CESS (Epstein-Barr virus-transformed human B cell line), MT-1 (HTLV-I-infected human T cell line without viral protein synthesis), and MT-2 (HTLV-I-infected human T cell line producing viral proteins).
(8) This frees the student to experience the excitement and challenge of learning and the joy of helping people.
(9) The role of O2 free radicals in the reduction of sarcolemmal Na+-K+-ATPase, which occurs during reperfusion of ischemic heart, was examined in isolated guinea pig heart using exogenous scavengers of O2 radicals and an inhibitor of xanthine oxidase.
(10) This sling was constructed bu freeing the insertion of the pubococcygeus and the ileococcygeus muscles from the coccyx.
(11) In Ca free-solution phenylephrine inhibited the response to CaCl2.
(12) The actuarial 5-year disease-free survival rates were 83% (group 1), 83% (group 2), and 100% (group 3).
(13) Their effects on various lipid fractions, viz., triglycerides (TG), phospholipids, free cholesterol, and esterified cholesterol, were studied in liver, plasma, gonads, and muscle.
(14) These deficiencies in the data compromise HIV surveillance based on diagnostic testing, and supplementary bias-free data are needed.
(15) The authors conclude that H. pylori alone causes little or no effect on an intact gastric mucosa in the rat, that either intact organisms or bacteria-free filtrates cause similar prolongation and delayed healing of pre-existing ulcers with active chronic inflammation, and that the presence of predisposing factors leading to disruption of gastric mucosal integrity may be required for the H. pylori enhancement of inflammation and tissue damage in the stomach.
(16) Only those derivatives with a free amino group and net positive charge in the side chain were effective.
(17) Under milder trypsin digestion conditions three resistant fragments were produced from the free protein.
(18) "This was very strategic and it was in line of the ideology of the Bush administration which has been to put in place a free market and conservative agenda."
(19) To determine the influence of cetylpyridinium chloride (CPC) adsorption on the wettability and elemental surface composition of human enamel, with and without adsorbed salivary constituents, surface-free energies and elemental compositions were determined.
(20) By growing purified human cytotrophoblasts under serum-free conditions and manipulating the culture surface, we were able to disassociate morphologic from biochemical differentiation.
Hep
Definition:
(n.) See Hip, the fruit of the dog-rose.
Example Sentences:
(1) Positive HEP values were obtained in 40 patients out of 42 with malignant tumours and in 5 patients out of 12 with other kidney diseases.
(2) Extracts were also prepared from vaccinia-infected HEp-2, RK and W-K cells respectively.
(3) One peptide, designated Hep III, which is thirteen amino acids in length and binds heparin, was active in directly promoting keratinocyte adhesion.
(4) An association between diarrhoea and high level adhesion was observed in that 12 of the 34 faecal isolates and none of the 29 environmental isolates yielded greater than 20 bacteria per HEp-2 cell in the adhesion assay.
(5) The secretion kinetics of nine proteins by Hep G2 cells in culture was investigated using pulse-chase techniques and immunoisolation of proteins with monospecific antibodies.
(6) This finding appeared to be due to Hep G2 cells expressing lipase activities which led to triacylglycerol and phospholipid hydrolysis and lipid reuptake.
(7) DT diaphorase, purified to homogeneity from human Hep G2 cells, did metabolize CB 1954 to this 4-hydroxylamino product, but the rate of CB 1954 reduction and thus production of the cytotoxic product, was much lower than that of purified Walker enzyme (ratio of Kcat = 6.4).
(8) By electron microscopy, E2348 was seen to adhere to HEp-2 cells in a manner that closely resembled EPEC adhesion to intestinal mucosa; bacteria were intimately attached to projections of the apical HEp-2 cell membrane and caused localized destruction of microvilli.
(9) These examinations showed that only the freshly isolated strain of Aa was found within the HEp-2 cells.
(10) B-PEO-HEP coated grafts still showed patency after 3 days.
(11) For poliovirus types 2 and 3 the observed differences in titres were highly significant (p = 0.001) between Hep 2C and Vero cells, Hep 2C and MRC-5 and also between Vero and MRC-5 cells, with higher titres on Hep 2C cells.
(12) R325-beta TK+, a herpes simplex virus 1 mutant carrying a 500-base-pair deletion in the alpha 22 gene and the wild-type (beta) thymidine kinase (TK) gene, was previously shown to grow efficiently in HEp-2 and Vero cell lines.
(13) Methods are described that are used for the titration of antinuclear, anticentromere, and anti-Scl-70 antibodies in systemic scleroderma, systemic lupus erythematosus, and rheumatoid arthritis: indirect immunofluorescence with various antigenic substrates (sections of fresh-frozen rat liver and Hep-2 cell culture), counter-current immunoelectrophoresis, isolation of Scl-70 antigen.
(14) The O157:H8 strains did not produce VT. All gave localised attachment to HEp-2 cells, associated with a positive fluorescence-actin staining test, and all hybridised with the E coli attaching and effacing (eae) probe.
(15) Hep G2 cells produce surplus A alpha and gamma fibrinogen chains.
(16) Adhesion may be studied in vitro systems using HeLa or HEp-2 cells, to which EPEC adhere in a localized pattern.
(17) The serum inhibitory effect appears limited to primary cells because no difference in Ad41 replication, as assayed by accumulation of Ad41 DNA, was found in infected continuous cell lines (HEp-2, 293) cultivated p.i.
(18) Additionally, the invasiveness of C. jejuni M96, a clinical isolate, was significantly increased for HEp-2 cells preinfected with coxsackievirus B3.
(19) Hep 5 impeded binding and degradation of 125I-labelled bovine LPL by perfused rat livers.
(20) To evaluate this possibility, three human cell lines, Hep G2, Hep 3B, and HA 22T, all thought to be arrested in different stages of differentiation based on their biochemical and morphological characteristics, were used as models.