What's the difference between free and manacle?

Free


Definition:

  • (superl.) Exempt from subjection to the will of others; not under restraint, control, or compulsion; able to follow one's own impulses, desires, or inclinations; determining one's own course of action; not dependent; at liberty.
  • (superl.) Not under an arbitrary or despotic government; subject only to fixed laws regularly and fairly administered, and defended by them from encroachments upon natural or acquired rights; enjoying political liberty.
  • (superl.) Liberated, by arriving at a certain age, from the control of parents, guardian, or master.
  • (superl.) Not confined or imprisoned; released from arrest; liberated; at liberty to go.
  • (superl.) Not subjected to the laws of physical necessity; capable of voluntary activity; endowed with moral liberty; -- said of the will.
  • (superl.) Clear of offense or crime; guiltless; innocent.
  • (superl.) Unconstrained by timidity or distrust; unreserved; ingenuous; frank; familiar; communicative.
  • (superl.) Unrestrained; immoderate; lavish; licentious; -- used in a bad sense.
  • (superl.) Not close or parsimonious; liberal; open-handed; lavish; as, free with his money.
  • (superl.) Exempt; clear; released; liberated; not encumbered or troubled with; as, free from pain; free from a burden; -- followed by from, or, rarely, by of.
  • (superl.) Characteristic of one acting without restraint; charming; easy.
  • (superl.) Ready; eager; acting without spurring or whipping; spirited; as, a free horse.
  • (superl.) Invested with a particular freedom or franchise; enjoying certain immunities or privileges; admitted to special rights; -- followed by of.
  • (superl.) Thrown open, or made accessible, to all; to be enjoyed without limitations; unrestricted; not obstructed, engrossed, or appropriated; open; -- said of a thing to be possessed or enjoyed; as, a free school.
  • (superl.) Not gained by importunity or purchase; gratuitous; spontaneous; as, free admission; a free gift.
  • (superl.) Not arbitrary or despotic; assuring liberty; defending individual rights against encroachment by any person or class; instituted by a free people; -- said of a government, institutions, etc.
  • (superl.) Certain or honorable; the opposite of base; as, free service; free socage.
  • (superl.) Privileged or individual; the opposite of common; as, a free fishery; a free warren.
  • (superl.) Not united or combined with anything else; separated; dissevered; unattached; at liberty to escape; as, free carbonic acid gas; free cells.
  • (adv.) Freely; willingly.
  • (adv.) Without charge; as, children admitted free.
  • (a.) To make free; to set at liberty; to rid of that which confines, limits, embarrasses, oppresses, etc.; to release; to disengage; to clear; -- followed by from, and sometimes by off; as, to free a captive or a slave; to be freed of these inconveniences.
  • (a.) To remove, as something that confines or bars; to relieve from the constraint of.
  • (a.) To frank.

Example Sentences:

  • (1) Cancer patients showed abnormally high plasma free tryptophan levels.
  • (2) In conclusion, the efficacy of free tissue transfer in the treatment of osteomyelitis is geared mainly at enabling the surgeon to perform a wide radical debridement of infected and nonviable soft tissue and bone.
  • (3) The authors have presented in two previous articles the graphic solutions resembling Tscherning ellipses, for spherical as well as for aspherical ophthalmic lenses free of astigmatism or power error.
  • (4) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
  • (5) With NaCl as the major constituent of the bathing solution (potassium-free pipette and external solutions) the reversal potential (Er) of the noradrenaline-evoked current was about 0 mV.
  • (6) In cardiac tissue the adenylate system is not a good indicator of the energy state of the mitochondrion, even when the concentrations of AMP and free cytosolic ADP are calculated from the adenylate kinase and creatine kinase equilibria.
  • (7) The promoters of the adenovirus 2 major late gene, the mouse beta-globin gene, the mouse immunoglobulin VH gene and the LTR of the human T-lymphotropic retrovirus type I were tested for their transcription activities in cell-free extracts of four cell lines; HeLa, CESS (Epstein-Barr virus-transformed human B cell line), MT-1 (HTLV-I-infected human T cell line without viral protein synthesis), and MT-2 (HTLV-I-infected human T cell line producing viral proteins).
  • (8) This frees the student to experience the excitement and challenge of learning and the joy of helping people.
  • (9) The role of O2 free radicals in the reduction of sarcolemmal Na+-K+-ATPase, which occurs during reperfusion of ischemic heart, was examined in isolated guinea pig heart using exogenous scavengers of O2 radicals and an inhibitor of xanthine oxidase.
  • (10) This sling was constructed bu freeing the insertion of the pubococcygeus and the ileococcygeus muscles from the coccyx.
  • (11) In Ca free-solution phenylephrine inhibited the response to CaCl2.
  • (12) The actuarial 5-year disease-free survival rates were 83% (group 1), 83% (group 2), and 100% (group 3).
  • (13) Their effects on various lipid fractions, viz., triglycerides (TG), phospholipids, free cholesterol, and esterified cholesterol, were studied in liver, plasma, gonads, and muscle.
  • (14) These deficiencies in the data compromise HIV surveillance based on diagnostic testing, and supplementary bias-free data are needed.
  • (15) The authors conclude that H. pylori alone causes little or no effect on an intact gastric mucosa in the rat, that either intact organisms or bacteria-free filtrates cause similar prolongation and delayed healing of pre-existing ulcers with active chronic inflammation, and that the presence of predisposing factors leading to disruption of gastric mucosal integrity may be required for the H. pylori enhancement of inflammation and tissue damage in the stomach.
  • (16) Only those derivatives with a free amino group and net positive charge in the side chain were effective.
  • (17) Under milder trypsin digestion conditions three resistant fragments were produced from the free protein.
  • (18) "This was very strategic and it was in line of the ideology of the Bush administration which has been to put in place a free market and conservative agenda."
  • (19) To determine the influence of cetylpyridinium chloride (CPC) adsorption on the wettability and elemental surface composition of human enamel, with and without adsorbed salivary constituents, surface-free energies and elemental compositions were determined.
  • (20) By growing purified human cytotrophoblasts under serum-free conditions and manipulating the culture surface, we were able to disassociate morphologic from biochemical differentiation.

Manacle


Definition:

  • (n.) A handcuff; a shackle for the hand or wrist; -- usually in the plural.
  • (v. t.) To put handcuffs or other fastening upon, for confining the hands; to shackle; to confine; to restrain from the use of the limbs or natural powers.

Example Sentences:

  • (1) • The Film weekly podcast saw host Jason Solomons talk to ... Bruce Robinson (director of Withnail & I) about his new film The Rum Diary ... Errol Morris (director of The Thin Blue Line) about Tabloid - his documentary on Joyce McKinney and the "Manacled Morman" case ... and Guardian film critic Xan Brooks (director of people to decent movies), who helped Jason review Arthur Christmas , The Awakening and Andrea Arnold's Wuthering Heights .
  • (2) Nyingi, who was detained for about nine years , beaten unconscious and bears the marks from leg manacles, whipping and caning, said: "For me … I just wanted the truth to be out.
  • (3) He was beaten unconscious and still bears the marks from leg manacles, whipping and caning.
  • (4) By humanism I mean first of all attempting to dissolve Blake's "mind-forg'd manacles" so as to be able to use one's mind historically and rationally for the purposes of reflective understanding.
  • (5) Too often he has seemed manacled when playing under Wilmots, whose decision to give him the captaincy was far from popular.
  • (6) When the claimants gave evidence at the high court in London last year, Wambugu Wa Nyingi told how he was detained on Christmas Eve 1952 and held for nine years, much of the time in manacles.
  • (7) Confronting it means shaking off the manacles it has imposed on our minds.
  • (8) There are clear analogies with old descriptions of the effects of torture by stretching from manacles or gauntlets or by the rack.
  • (9) One of the high-court claimants, Wambugu Wa Nyingi described how he was detained in 1952 , held for nine years, much of the time in manacles, and beaten unconscious during a particularly notorious massacre at a camp at Hola in which 11 men died.
  • (10) The documents detailed the way suspected insurgents had been beaten to death, burned alive, castrated – like two of the high court claimants – and kept in manacles for years.
  • (11) Robert Holcomb, one of those interviewed in Bloods, Terry's oral history of the war by black veterans, describes how, after being hounded by the FBI, he was "sworn into the army in manacles".