(superl.) Exempt from subjection to the will of others; not under restraint, control, or compulsion; able to follow one's own impulses, desires, or inclinations; determining one's own course of action; not dependent; at liberty.
(superl.) Not under an arbitrary or despotic government; subject only to fixed laws regularly and fairly administered, and defended by them from encroachments upon natural or acquired rights; enjoying political liberty.
(superl.) Liberated, by arriving at a certain age, from the control of parents, guardian, or master.
(superl.) Not confined or imprisoned; released from arrest; liberated; at liberty to go.
(superl.) Not subjected to the laws of physical necessity; capable of voluntary activity; endowed with moral liberty; -- said of the will.
(superl.) Clear of offense or crime; guiltless; innocent.
(superl.) Unconstrained by timidity or distrust; unreserved; ingenuous; frank; familiar; communicative.
(superl.) Unrestrained; immoderate; lavish; licentious; -- used in a bad sense.
(superl.) Not close or parsimonious; liberal; open-handed; lavish; as, free with his money.
(superl.) Exempt; clear; released; liberated; not encumbered or troubled with; as, free from pain; free from a burden; -- followed by from, or, rarely, by of.
(superl.) Characteristic of one acting without restraint; charming; easy.
(superl.) Ready; eager; acting without spurring or whipping; spirited; as, a free horse.
(superl.) Invested with a particular freedom or franchise; enjoying certain immunities or privileges; admitted to special rights; -- followed by of.
(superl.) Thrown open, or made accessible, to all; to be enjoyed without limitations; unrestricted; not obstructed, engrossed, or appropriated; open; -- said of a thing to be possessed or enjoyed; as, a free school.
(superl.) Not gained by importunity or purchase; gratuitous; spontaneous; as, free admission; a free gift.
(superl.) Not arbitrary or despotic; assuring liberty; defending individual rights against encroachment by any person or class; instituted by a free people; -- said of a government, institutions, etc.
(superl.) Certain or honorable; the opposite of base; as, free service; free socage.
(superl.) Privileged or individual; the opposite of common; as, a free fishery; a free warren.
(superl.) Not united or combined with anything else; separated; dissevered; unattached; at liberty to escape; as, free carbonic acid gas; free cells.
(adv.) Freely; willingly.
(adv.) Without charge; as, children admitted free.
(a.) To make free; to set at liberty; to rid of that which confines, limits, embarrasses, oppresses, etc.; to release; to disengage; to clear; -- followed by from, and sometimes by off; as, to free a captive or a slave; to be freed of these inconveniences.
(a.) To remove, as something that confines or bars; to relieve from the constraint of.
(a.) To frank.
Example Sentences:
(1) Cancer patients showed abnormally high plasma free tryptophan levels.
(2) In conclusion, the efficacy of free tissue transfer in the treatment of osteomyelitis is geared mainly at enabling the surgeon to perform a wide radical debridement of infected and nonviable soft tissue and bone.
(3) The authors have presented in two previous articles the graphic solutions resembling Tscherning ellipses, for spherical as well as for aspherical ophthalmic lenses free of astigmatism or power error.
(4) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(5) With NaCl as the major constituent of the bathing solution (potassium-free pipette and external solutions) the reversal potential (Er) of the noradrenaline-evoked current was about 0 mV.
(6) In cardiac tissue the adenylate system is not a good indicator of the energy state of the mitochondrion, even when the concentrations of AMP and free cytosolic ADP are calculated from the adenylate kinase and creatine kinase equilibria.
(7) The promoters of the adenovirus 2 major late gene, the mouse beta-globin gene, the mouse immunoglobulin VH gene and the LTR of the human T-lymphotropic retrovirus type I were tested for their transcription activities in cell-free extracts of four cell lines; HeLa, CESS (Epstein-Barr virus-transformed human B cell line), MT-1 (HTLV-I-infected human T cell line without viral protein synthesis), and MT-2 (HTLV-I-infected human T cell line producing viral proteins).
(8) This frees the student to experience the excitement and challenge of learning and the joy of helping people.
(9) The role of O2 free radicals in the reduction of sarcolemmal Na+-K+-ATPase, which occurs during reperfusion of ischemic heart, was examined in isolated guinea pig heart using exogenous scavengers of O2 radicals and an inhibitor of xanthine oxidase.
(10) This sling was constructed bu freeing the insertion of the pubococcygeus and the ileococcygeus muscles from the coccyx.
(11) In Ca free-solution phenylephrine inhibited the response to CaCl2.
(12) The actuarial 5-year disease-free survival rates were 83% (group 1), 83% (group 2), and 100% (group 3).
(13) Their effects on various lipid fractions, viz., triglycerides (TG), phospholipids, free cholesterol, and esterified cholesterol, were studied in liver, plasma, gonads, and muscle.
(14) These deficiencies in the data compromise HIV surveillance based on diagnostic testing, and supplementary bias-free data are needed.
(15) The authors conclude that H. pylori alone causes little or no effect on an intact gastric mucosa in the rat, that either intact organisms or bacteria-free filtrates cause similar prolongation and delayed healing of pre-existing ulcers with active chronic inflammation, and that the presence of predisposing factors leading to disruption of gastric mucosal integrity may be required for the H. pylori enhancement of inflammation and tissue damage in the stomach.
(16) Only those derivatives with a free amino group and net positive charge in the side chain were effective.
(17) Under milder trypsin digestion conditions three resistant fragments were produced from the free protein.
(18) "This was very strategic and it was in line of the ideology of the Bush administration which has been to put in place a free market and conservative agenda."
(19) To determine the influence of cetylpyridinium chloride (CPC) adsorption on the wettability and elemental surface composition of human enamel, with and without adsorbed salivary constituents, surface-free energies and elemental compositions were determined.
(20) By growing purified human cytotrophoblasts under serum-free conditions and manipulating the culture surface, we were able to disassociate morphologic from biochemical differentiation.
Purge
Definition:
(v. t.) To cleanse, clear, or purify by separating and carrying off whatever is impure, heterogeneous, foreign, or superfluous.
(v. t.) To operate on as, or by means of, a cathartic medicine, or in a similar manner.
(v. t.) To clarify; to defecate, as liquors.
(v. t.) To clear of sediment, as a boiler, or of air, as a steam pipe, by driving off or permitting escape.
(v. t.) To clear from guilt, or from moral or ceremonial defilement; as, to purge one of guilt or crime.
(v. t.) To clear from accusation, or the charge of a crime or misdemeanor, as by oath or in ordeal.
(v. t.) To remove in cleansing; to deterge; to wash away; -- often followed by away.
(v. i.) To become pure, as by clarification.
(v. i.) To have or produce frequent evacuations from the intestines, as by means of a cathartic.
(v. t.) The act of purging.
(v. t.) That which purges; especially, a medicine that evacuates the intestines; a cathartic.
Example Sentences:
(1) Thus photosensitization using AISPc may be an effective method of purging marrow autografts in some cases of AML.
(2) Current investigations include the development of more effective cytoreductive regimens, use of recombinant hematopoietic growth factors, improvement of marrow purging techniques, and enhancement of cell-mediated anti-leukemic activity in patients receiving autologous marrow transplants.
(3) Direct detection of chromium in milk, using only argon as purge gas, was inferior.
(4) Indiana Indiana began to purge inactive voters in may 2014 by sending postcards to all registered voters.
(5) Sequential application of the two methods (immunorosette depletion with CD19 McAb followed by a complement lysis with CD9 and CD10 McAbs) led to superior results in causing a 4- to 5-log purging effect.
(6) Reduced caloric intake, a hallmark of both disorders, is manifested by self-induced starvation in anorexia and by binge eating and gastrointestinal purging in bulimia.
(7) Mafosfamide is presently used for the purging of bone marrow in autologous bone marrow transplantation in the treatment of acute leukemia.
(8) The two log difference in the surviving fraction of CFU-L and CFU-S after 120 min exposure to 42.5 degrees C suggests that hyperthermia ex vivo may be a suitable purging method for autologous bone marrow transplantation.
(9) There are already calls for large protests in Egypt this week demanding fair trials and retribution, as well as measures to purge former regime officials from political and economic life.
(10) Our data suggest that this new strategy shows potential for more effective ex vivo marrow purging in autologous marrow transplantation for acute lymphoblastic leukemia.
(11) In summary, laser light-induced photosensitization with MC540 has a selective cytotoxicity to leukemic cells; therefore, this procedure may be useful for purging neoplastic cells from autologous BM.
(12) Pretransplantation regimes were: total-body irradiation (TBI), 456; busulfan plus cyclophosphamide (BU-CY) 174; marrow purging with mafosfamide, 269 (corresponding to 26% of all patients in CR1 and 41% in CR2).
(13) Phase 1 studies of "in vivo purging" with a monovalent CD3 antibody (Clark et al., 1989), and also with a genetically engineered humanized IgG1 (CAMPATH-1H) (Hale et al., 1988b) suggest that these limitations can be overcome.
(14) Despite patient and disease heterogeneity, different sources of hemopoietic stem cells (allogeneic or autologous, bone marrow or blood), ex vivo purging of autografts, and different preparative regimens, some general recommendations can be made: (1) Allogeneic BMT should be reserved for patients under age 50, where transplant-related mortality can be expected not to exceed 30%; 40% will achieve CR with a 3-year relapse-free survival expectation of 70%, and (2) With autologous transplantation, low mortality under 10% and marked therapeutic benefit (greater than 30% CR, 80% overall survival at greater than 3 years) seem to be achievable mainly if performed when tumor bulk is low and standard doses of therapy are still effective.
(15) The transfusion purging leukocytes may diminish the occasions of alloimmunization.
(16) The Brotherhood's Libyan incarnation won only 10% of the vote in last year's congressional elections, but gained support with its campaign to mandate wholesale purges of Gaddafi-era officials.
(17) We feel that this system will prove valuable for monitoring ex vivo tumor removal in future clinical studies and should be considered for use in other purging trials.
(18) The quantitative determination of the efficacy of these purging methods is generally difficult.
(19) The government began aggressively purging the heads of cultural and academic institutions (a notable number of them Jewish and liberal intellectuals suspected of a “foreign” mindset) and installing in their stead true believers in the Magyar way.
(20) The result of our study in patients in second and third remission using in vitro purging of bone marrow with monoclonal antibodies PM-81 and AML2-23 are encouraging, as are the studies of purging with 4-HC.