(a.) A die; a half-round set hammer, used for forming grooves and spreading iron; -- called also a creaser.
(v. t.) To form a groove or channel in, by a fuller or set hammer; as, to fuller a bayonet.
Example Sentences:
(1) The results indicated that neuropsychological measures may serve to broaden the concept of intelligence and that a brain-related criterion may contribute to a fuller understanding of its nature.
(2) Matthew Fuller, 25, Rueben Barnes, 16, and Mitchell Sweeney, 22, died from electrocution and Marcus Wilson, 19, died after installing insulation batts in extreme heat.
(3) First in line was Conservative Richard Fuller, who he believed was looking at him in a funny way.
(4) The initiative, co-ordinated by the chairman of sportswear brand Skins, Jaimie Fuller, was also backed by Tory MP Damian Collins.
(5) The combination of T7 RNA polymerase, T7 DNA polymerase, and T7 gene 4 protein initiates DNA synthesis in vitro within the cloned origin sequence (Fuller, C. W., and Richardson, C. C. (1985) J. Biol.
(6) In an open letter to the college Fran Fuller, chair of BASW, says that the plans were a surprise, as the organisations have a memorandum of understanding in place and have spent "many weeks" positively discussing the college's development.
(7) "Sir Jeremy could and should have advised the prime minister to refer the allegations of ministerial misconduct to the prime minister's adviser for a fuller investigation.
(8) In addition, because a firm understanding of basic laser-tissue interactions is key to knowledgeably and sensibly using lasers, regardless of the delivery mode, we present an overview of some basic principles; readers interested in a greater level of detail should consult other sources for a fuller understanding of the issues.
(9) If the CMA goes ahead with a preliminary investigation it will have 40 working days to clear the deal, seek remedies or move to a fuller inquiry that could take six months.
(10) Fuller's XIX Entertainment, pointedly thanked by the player on Thursday, was responsible for creating "Brand Beckham" and a string of global marketing deals.
(11) NSW police announce first bomb amnesty – but just don't bring them in Read more Fuller said there was a “new phenomenon” of people who may be at risk of committing violent acts that did not fit into the traditional profile police had established of potential terrorism suspects.
(12) As a charity that campaigns on issues of women’s economic equality, we take these allegations extremely seriously and will do our utmost to investigate them … we remain confident that we took every practicable and reasonable step to ensure that the range would be ethically produced and await a fuller understanding of the circumstances under which the garments were produced.” When the Fawcett Society sought reassurance about standards at the factory, Whistles emailed back to say CMT is “a fully audited, socially and ethical compliant factory” and cited accreditations relating to the provenance and content of materials.
(13) A separate proposal suggested that companies provide "fuller information on the relationship between pay and company performance".
(14) An important key to the resolution of these debates lies in attaining a fuller understanding of the morphological differences in skull form between the African and Asian great apes.
(15) Four men died while installing home insulation – Matthew Fuller, Reuben Barnes, Mitchell Sweeney and Marcus Wilson.
(16) Fuller claimed that The X Factor has stolen parts of the Pop Idol format and took legal action.
(17) Trustees are appealing for more information, pictures and stories from veterans or their relatives to paint a fuller picture of life at Bletchley Park, where 20 years of campaigning for recognition of its importance, plus restoration and developments have turned it into a tourist attraction.
(18) The result suggest that higher response rates may be achieved in studies of cancer if fuller disclosure of the study purposes is made.
(19) It was entirely characteristic of Ross that 15 years later, when he had virtually given up book-publishing, he should have revived the LME imprint to produce two hardbacks by his old and abruptly publisherless friend Roy Fuller, and made a great success of them.
(20) 1977a: Fink, 1986: Fishb ein & Griffin, 1976: Fujikawa, 1981: Fuller & De Loecker, 1985: Lazarus et al.
Groove
Definition:
(n.) A furrow, channel, or long hollow, such as may be formed by cutting, molding, grinding, the wearing force of flowing water, or constant travel; a depressed way; a worn path; a rut.
(n.) Hence: The habitual course of life, work, or affairs; fixed routine.
(n.) A shaft or excavation.
(v. t.) To cut a groove or channel in; to form into channels or grooves; to furrow.
Example Sentences:
(1) The ligands bind at discrete sites in the minor groove of DNA, and analysis on DNA sequencing gels show pronounced protection at the ligand binding sites, as well as more generalized protection.
(2) Recent reports have indicated the usefulness of nuclear grooves (clefts or notches) as an additional criterion for the diagnosis of papillary thyroid carcinoma in fine needle aspirates; most of these studies were carried out on alcohol-fixed material stained with the Papanicolaou stain or with hematoxylin and eosin, which yield good nuclear details.
(3) Intermolecular contacts occur in both oligomers in the minor groove: in the B form through twisted guanine-guanine hydrogen bonding, and in the Z form through base-base stacking and the water network.
(4) The nogalose and aminoglucose sugars lie in the minor and major grooves, respectively, of the distorted B-DNA double helix.
(5) The AFB1 moiety is face-stacked in the major groove with its long axis approximately perpendicular to the helix axis.
(6) These results strongly indicate that metallobleomycin binds in the minor groove of B-DNA and that the 2-amino group of guanine adjacent to the 5' side of the cleaved pyrimidine base is one key element of the specific 5' G-C or G-T recognition by the bleomycin-metal complex.
(7) As a basis for the discussion a possible structure for the DNA complex of the phenylated neutral red is considered in which the extra phenyl ring at N-5 of the phenazinium system, protrudes into the large groove of the DNA helix while the tricyclic part of the ligand is inserted between the DNA base-pairs.
(8) A high intensity of the reactions was observed in certain cells of the neural groove in 24-hours' embryos and in the neural tube of 48-hours' embryos.
(9) Recent STM studies of calf thymus DNA and poly(rA).poly(rU) have shown that the helical pitch and periodic alternation of major and minor grooves can be visualized and reliably measured.
(10) In the absence of boxes or grooves, pins markedly enhanced both retention and resistance.
(11) Therefore in artificial knee replacement a lateral tilt of the patella sliding groove should not be propagated as 'physiological'.
(12) Many antitumor drugs, and many carcinogens, act by binding within the minor groove of double-helical DNA, interfering with both replication and transcription.
(13) This instrument, a modification of a corneal trephine, provides a neat, smooth groove of adjustable depth.
(14) and the fluid ejected from the ejaculatory groove region (about 0.2 ml.).
(15) 3) The significance of minor groove Mtase-DNA interactions to specificity is confirmed.
(16) (v) The bis-benzimidazole drug Hoechst-33258, which binds in the minor groove of B-DNA, exhibits very little fluorescence in the presence of the ps hairpins but a normal, enhanced emission with the aps oligonucleotides.
(17) We have studied the time-resolved and the steady-state fluorescence of the DNA groove binders 4',6-diamidino-2-phenylindole (DAPI) and Hoechst 33258 with the double stranded DNAs poly(dA-dU) and poly(dI-dC) and their halogenated analogs, poly(dA-I5dU) and poly(dI-Br5dC).
(18) The complexation-induced chemical shifts and NOE cross peaks in the NOESY map of the 1:1 complex of lexitropsin (1) and d-[CGCAATTGCG]2 reveal that the thiazole ring of the lexitropsin (1) intercalates between dA4.A5 bases and the rest of the ligand resides in the minor groove of the AT rich core of decamer, thus occupying the 5'-AATT sequence on the DNA.
(19) All cases had true hypertelorism and a median nasal groove with absence of the nasal tip.
(20) Distamycin, Hoechst 33258, and DAPI were used as agents capable of AT-specific binding in the minor groove of DNA while producing no profound long-range distortion of DNA structure.