(n.) A spout projecting from the roof gutter of a building, often carved grotesquely.
Example Sentences:
(1) Their intellect is normal and they have no gargoyle-like features.
(2) Bill Nighy plays the king of the demons; Miranda Otto the gargoyle queen.
(3) beta-Mannosidase deficiency was demonstrated in fibroblasts of a girl who showed severe psychomotor retardation, bone deformities and gargoylism and recurrent skin and respiratory infections and who died at 20 years of age from bronchopneumonia.
(4) In various tissues from patients with gargoylism, deficiency of beta-galactosidase A could be demonstrated.
(5) The high level of mannose in the liver from gargoylism patients seems to indicate storage of glycopeptide, adding a new group of substances to those known to be stored in gargoylism.
(6) An autopsy case of a 19-year-old boy who had shown typical gargoyle features, strictly consistent with mucopolysaccharidosis type II (Hunter's syndrome) was reported.
(7) The reversed conditions could be caused by the difference of increased aMPS; i.e., dermatan sulfate B or heparitin sulfate in gargoylism, on the contrary, dermatan sulfate A and C or hyaluronic acid in Marfan syndrome.
(8) An adult patient with macular cherry-red spots, a gargoyle-like physical appearance, cerebellar ataxia, myoclonus, convulsive seizures, and pyramidal tract signs showed a profound deficiency of beta-galactosidase in liver and brain.
(9) The patient had a gargoyle-like face, bone change with cherry-red spot and absence of mucopolysacchariduria, and moreover accompanied by hereditary thrombocytopathy and color blindness.
(10) The nature of the basic defect in gargoylism is discussed.
(11) It must however be mentioned that the most frequent mucopolysaccharidosis, Sanfilippo's disease, and other forms of mucopolysaccharidoses (MPSoses) are not showing gargoylism.
(12) As grim as a gargoyle, craggy as a crag, jaw set in steel – even the famous smirk was well hidden behind the scowl.
(13) The present paper describes 3 out of a total of 9 siblings, aged 9, 17, and 18, with the following symptoms: gargoyle-like facial features, clouding of the cornea in both eyes, dysostosis multiplex, slightly impaired intelligence, hepatosplenomegaly, umbilical hernia, and increased secretion of mucopolysaccharides in the urine, in particular dermatan and heparan sulfate.
(14) Cellulose acetate electrophoresis differentiated clearly between the two major forms of gargoylism, the Hurler and Sanfilippo syndromes, but differentiation between the Hurler, Hunter, and Scheie syndromes was more difficult on electrophoretic data alone.
(15) The samples analyzed were obtained from control subjects, patients with gargoylism, and patients with a few other kinds of storage disorders.
(16) Studies in the morphology, histochemistry, and ultrastructure of the cerebellum, with special reference to the Purkinje cell dendrites, have been undertaken in eight cases of gargoylism.
(17) Still though, the obsession with personality, the grand gargoyles of the dugout over, say, tactics and development remains.
(18) In newspapers, cartoons squat like gargoyles on top of the columns, and while you nibble your way through the columnists' prose for several minutes, you swallow the cartoon whole in seconds.
(19) An autopsy case of a 9 years and 5 months old gargoyle girl diagnosed as Sanfilippo B syndrome by the biochemical demonstration of a large amount of heparan sulfate in urine and some organs and of deficiency of alpha-N-acetyl-D-glucosaminidase in the liver and brain was reported.
(20) A 17-year-old patient clinically manifesting gargoyle face, dwarfism, skeletal bone deformity, mild mental retardation and benign course was presented.
Gutter
Definition:
(n.) A channel at the eaves of a roof for conveying away the rain; an eaves channel; an eaves trough.
(n.) A small channel at the roadside or elsewhere, to lead off surface water.
(n.) Any narrow channel or groove; as, a gutter formed by erosion in the vent of a gun from repeated firing.
(v. t.) To cut or form into small longitudinal hollows; to channel.
(v. t.) To supply with a gutter or gutters.
(v. i.) To become channeled, as a candle when the flame flares in the wind.
Example Sentences:
(1) This is basically a large tank (the bigger the better) that collects rain from the house guttering and pumps it into the home, to be used for flushing the loo.
(2) These lanes encourage cyclists to 'ride in the gutter' which in itself is a very dangerous riding position – especially on busy congested roads as it places the cyclist right in a motorist's blind spot.
(3) The size of presynaptic release site structures was determined by examining serial transverse sections through entire terminal branches with the transmission electron microscope; the size of postsynaptic release site structures was determined by examining terminal gutters with the scanning electron microscope after the removal of terminal branches.
(4) Yes, Goldsmith is to be held in contempt: a man of decency would have rejected this gutter strategy.
(5) More time in bed, more time with the kids, more time to read, see your mum, hang out with friends, repair the guttering, make music, fix lunch, walk in the park.
(6) Had they bothered to inquire of a veteran from the ranks, they might have heard how exasperating it is to see the dainty long-range patriots of Labour thrashing it out with the staunch gutter jingoists of the Conservative party – and barely a non-commissioned vet among them.
(7) No clear gross or histological distinctions between the ventricular "candle gutterings" and "tumors" have been identified.
(8) Most transposed ovaries were located along the paracolic gutters near the iliac crests, creating an extrinsic mass effect on adjacent bowel.
(9) Golf balls, bottles, fireworks, umbrellas and even cast iron rain gutter was thrown at republicans marching along Royal Avenue.
(10) !— she wants you to put out the bins and clear the gutters of leaves like you’ve been promising to do for six months.
(11) A one-piece integral tube and plate with a slit-valve mechanism designed to regulate post-operative intraocular pressure had a very variable response in 27 eyes, with mean pressures similar to those after unligated tube and gutters.
(12) Blood gutters brightly against his green gown, yet the man doesn't shudder or stagger or sink but trudges towards them on those tree-trunk legs and rummages around, reaches at their feet and cops hold of his head and hoists it high, and strides to his steed, snatches the bridle, steps into the stirrup and swings into the saddle still gripping his head by a handful of hair.
(13) In the second, density would decrease from the crest border, where the value was that of the gutter edge, to the fold end, where the value would be 50% lower.
(14) Following the sting, Ferguson apologised for a “serious lapse of judgment” and told the US talkshow host Oprah Winfrey she had been drinking and was “in the gutter at that moment”.
(15) The characteristics of the innervation revealed by the cholinesterase activity, concentrated in the synaptic gutters and the direct study of the nerve fibres, show focal, mono-axonal 'en plaques' endings, typical of the phasic motor system.
(16) The flame of ultra Serb nationalism appears to be guttering, although it could be replaced with a quieter long-lasting resentment.
(17) For larger exposure of the artery, the foramen transversarium of C1 must be unroofed and the artery dissected in the guttering of the posterior arch of the atlas.
(18) In a surgical technique termed ovarian transposition, the ovary is repositioned to the iliac fossa or paracolic gutter outside the radiation field.
(19) That “trollumnist” Mark Latham, that “misogynist”, “venal”, “crazy-eyed moron” whose views should be “rejected and dismantled and kicked into the gutter where they belong” has resigned from the Australian Financial Review.
(20) This comes from a man who insisted on a mass cull of badgers against scientific advice , who stripped away the last regulations protecting the soil from erosion , who believed that “ the purpose of waterways is to get rid of water ” and sought to turn our rivers into featureless gutters ,and who championed the pesticides that appear to be destroying bees and other animals .