(1) A search for other mutations in N-RAS exon-1 in T-ALL revealed a codon 13 mutation substituting aspartic acid (GAT) for glycine (GGT) in one of 18 patients.
(2) Thus, these data physically verify the serological characteristics of GAT-TsF1 that were originally defined solely on the basis of biological activity.
(3) We found that the cell-associated form of a factor specific for L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT-TsF1) is a 66 kDa protein which exhibits a slightly acidic isoelectric point, but no carbohydrate as determined by enzymatic analysis and lectin-affinity chromatography.
(4) Thus, helper T cells can serve as the cellular target of antigen-specific, MHC-restricted GAT-TsF2, and cloned helper T cells can be used as a homogeneous target population for analysis of the molecular mechanisms of T cell suppression.
(5) The maternal defect was shown to be a frameshift mutation with the deletion of a single T in the aspartic acid codon at position 690 (GAT), 11 amino acids N-terminal to the beginning of the transmembrane domain.
(6) The small inequality tau re gat greater than tau off2 suggests that charges which have returned from immobilization are not immediately available for displacement.
(7) Simultaneous immunization in vivo with the various GAT-Mphi or GAT-MBSA plus soluble GAT modulated the response pattern of these F(1) spleen cells such that they developed secondary responses only to F(1) and parental responder GAT-Mphi regardless of the response pattern observed after immunization with the various GAT-Mphi or GAT-MBSA alone.
(8) Two clonal cell lines, Cl-3 and Cl-7, were cloned from the PC-1 cell line, and these cell lines also carried the GAT point mutation at codon 12.
(9) Body weight was affected by Ea-B, Ir-GAT, and the interaction between Ea-B and Ir-GAT, but not by interaction with RSV response.
(10) The Charity Commission, which has already opened a case against the GAT, has been told of footage obtained by ITV’s Exposure: Charities Behaving Badly documentary.
(11) These results showed that immunization of (responder X responder)F1 mice with parental GAT-M phi results in the development of antigen-specific helper and suppressor T cells.
(12) The Plowell allele was shown in one M3P heterozygous individual to be due to a GAT(Asp) to GTT(Val) change at codon 256, in agreement with a previous study based on hybridization with allele-specific oligonucleotides.
(13) T cell subsets from virgin and immunized mice, which are Ir gene controlled nonresponders to GAT, which regulate antibody responses to GAT have been characterized.
(14) When cultured in the presence of exogenous rIL-2 as a growth factor, GAT-specific Th cell lines secreted mainly IL-4, whereas bacillus Calmette Guérin-specific lines produced predominantly IL-2.
(15) Addition of GAT to cultures of spleen cells from nonresponder mice also prevents development of the GAT-specific PFC responses stimulated by GAT-MBSA.
(16) Anti-idiotypic antisera made against each of the 15 hybridoma anti-GAT antibodies preferentially bound homologous ligand and showed minimal binding activity to specifically purified serum anti-GAT antibodies.
(17) The inequality tau re gat greater than tau re Na was larger and statistically significant at -100 and -110 mV.
(18) Haplotypes with high antibody responses to GAT had significantly higher antibody titers to PM and MG vaccines than haplotypes with low antibody responses.
(19) In contrast, the Th cell line 52.3 used as control could be induced to express high levels of IL2R only after exposure to GAT; nevertheless, IL2 seems to play a critical role in the in vitro survival of the resting state of 52.3 T cells.
(20) These results suggest that posttranslational modification, including glycosylation, is not required for biological activity or for expression of the I-J epitope on the GAT-TsF2 molecule.
Gun
Definition:
() of Gin
(n.) A weapon which throws or propels a missile to a distance; any firearm or instrument for throwing projectiles by the explosion of gunpowder, consisting of a tube or barrel closed at one end, in which the projectile is placed, with an explosive charge behind, which is ignited by various means. Muskets, rifles, carbines, and fowling pieces are smaller guns, for hand use, and are called small arms. Larger guns are called cannon, ordnance, fieldpieces, carronades, howitzers, etc. See these terms in the Vocabulary.
(n.) A piece of heavy ordnance; in a restricted sense, a cannon.
(n.) Violent blasts of wind.
(v. i.) To practice fowling or hunting small game; -- chiefly in participial form; as, to go gunning.
Example Sentences:
(1) Biden will meet with representatives from six gun groups on Thursday, including the NRA and the Independent Firearms Owners Association, which are both publicly opposed to stricter gun-control laws.
(2) Where he has taken a stand, like on gun control after the shootings in Newtown, Connecticut, Obama was unable to achieve legislative change.
(3) The information about her father's semi-brainwashing forms an interesting backdrop to Malala's comments when I ask if she ever wonders about the man who tried to kill her on her way back from school that day in October last year, and why his hands were shaking as he held the gun – a detail she has picked up from the girls in the school bus with her at the time; she herself has no memory of the shooting.
(4) One might expect that a similar news spike and rebounding of support for stricter gun control can happen, given President Obama's new push.
(5) But at least one customer signalled that America's gun lobby might be on the cusp of a moment of introspection.
(6) The Guardian neglects to mention 150,000 privately owned guns or that Palestinians are banned from bearing arms.
(7) said Wanis Kilani, a uniformed rebel driving a pickup truck with a machine-gun mounted on the back.
(8) At one, in the Gun and Dog pub in Leeds on Tuesday, a witness described how the meeting descended into chaos when one of the rebels smashed a glass and threatened to attack Griffin supporter Mark Collett.
(9) Asked if France had “jumped the gun and didn’t tell us”, Fox said he was notaware of anyone in government who knew about the impending airstrikes.
(10) "He [Copernicus] stuck to his guns when he came under fire for it, and he was right."
(11) In combination, the features of these vectors afford useful advantages over expression vectors previously described, especially for the application of shot-gun cloning of genomic DNA to generate expression libraries.
(12) Hours after the firefight ended, and just a few dozen kilometres away, a "very reliable" member of the Afghan local police turned his gun on two British soldiers.
(13) I went to see the Who recently, which was fantastic, but the band I truly love has to be the one I first got into, Guns N' Roses.
(14) Regarding the shots fired from Brelo’s gun, O’Donnell said they could have been the ones causing death, but so could others fired by other officers before his shots from the hood of the vehicle.
(15) He casts his history of bipartisan negotiation as a form of steamrolling practicality, and many of his actual policies, save regarding gun control, fit comfortably within the far right framework.
(16) Trying to escape, speaker Mohammed Magariaf's jeep was hit by a fusillade of machine-gun fire.
(17) When the vote came, she and the other gun law advocates who crowded into the public gallery had been told not to talk, stand or take notes.
(18) Following a mass killing at a Colorado cinema in July, applications to buy guns rose more than 40% in a week.
(19) The coroner also raised concerns that although the aim of the operation in which Duggan was killed was to take guns off the streets, little attempt was made to seize weapons believed to be held by Hutchinson-Foster.
(20) Any unilateral action by the president seemed sure to inflame gun advocates, who argue that gun sales are protected under the second amendment and who equate gun control with tyranny.