(n.) A narrow ornamental fabric of silk, woolen, or cotton, often with a metallic wire, or sometimes a coarse cord, running through it; -- used as trimming for dresses, furniture, etc.
(v. t.) To notch; to indent; to jag.
Example Sentences:
(1) British Cycling, Will’s Wheels and the curious case of 2,200 pieces of GB kit Read more Drake said: “I have never been made aware, formally or informally, of any allegation that Shane Sutton had used the offensive term ‘gimps’ in reference to Paralympic athletes prior to the media reports of the past few days.
(2) I do like people.” What they say “At the risk of ruining the honourable gentleman’s reputation as Thatcher’s gimp – I mean toy boy – may I enormously commend him for the work he has done as [select] committee chair for the past 10 years” – Chris Bryant MP
(3) PT: Photoshop is standard; though it certainly won’t hurt if you get good with GIMP, which is completely free.
(4) But BrewDog got to denounce Diageo as “a band of dishonest hammerheads and dumb-ass corporate freaks”, and to affirm that the incident showed “just how scared and jealous the gimp-like establishment are of the craft beer revolutionaries”.
(5) As well as woozily offering Mark Ronson a sip of his gin, we also got to witness him confessing his love for gimp masks; playing “ hide the banana ”; and an excruciating “bit” with blind tenor Andrea Bocelli in which he stammered “Nice to, erm, see you”.
(6) A kind of unshaven, post-watershed, post-divorce and redundancy Johnny Bravo whose style inspiration sits somewhere between matador and gimp.
(7) The localization and chemical characteristics of two Golgi integral membrane proteins (GIMPs) have been studied using monoclonal antibodies.
(8) Both GIMPs are glycoproteins that contain N- and O-linked carbohydrates.
(9) In an email to the Guardian Mellor said: “‘Get those Fucking Gimps’ was a phrase that was used by Shane [Sutton] and I confirm was ignored by Ian Drake when raised by me.” Mellor also stated that in his view the Paralympic athletes were discriminated against when it came to resources, for example travelling at times without a doctor or, on one occasion, being asked to scrap a training camp when the able‑bodied team’s budget fell short.
(10) Documents from Mellor’s evidence shown to the Guardian cited an episode in which Sutton was described as coming to the coach’s office and shouting “get those fucking gimps off the track”.
(11) It’s tempting to compare them to Late Night Gimp Fight, their predecessors as the fringe’s go-to troupe for “blood, poo and bumholes” (their words) comedy.
(12) But he was left with little option but to resign after he was also accused of calling members of Britain’s hugely successful Paralympic cycling squad “wobblies” and “gimps”.
(13) The young sketch troupe Late Night Gimp Fight were entirely unapologetic about their scene at Edinburgh last month, in which Sleeping Beauty wasn't kissed awake by her prince, but raped instead.
Groove
Definition:
(n.) A furrow, channel, or long hollow, such as may be formed by cutting, molding, grinding, the wearing force of flowing water, or constant travel; a depressed way; a worn path; a rut.
(n.) Hence: The habitual course of life, work, or affairs; fixed routine.
(n.) A shaft or excavation.
(v. t.) To cut a groove or channel in; to form into channels or grooves; to furrow.
Example Sentences:
(1) The ligands bind at discrete sites in the minor groove of DNA, and analysis on DNA sequencing gels show pronounced protection at the ligand binding sites, as well as more generalized protection.
(2) Recent reports have indicated the usefulness of nuclear grooves (clefts or notches) as an additional criterion for the diagnosis of papillary thyroid carcinoma in fine needle aspirates; most of these studies were carried out on alcohol-fixed material stained with the Papanicolaou stain or with hematoxylin and eosin, which yield good nuclear details.
(3) Intermolecular contacts occur in both oligomers in the minor groove: in the B form through twisted guanine-guanine hydrogen bonding, and in the Z form through base-base stacking and the water network.
(4) The nogalose and aminoglucose sugars lie in the minor and major grooves, respectively, of the distorted B-DNA double helix.
(5) The AFB1 moiety is face-stacked in the major groove with its long axis approximately perpendicular to the helix axis.
(6) These results strongly indicate that metallobleomycin binds in the minor groove of B-DNA and that the 2-amino group of guanine adjacent to the 5' side of the cleaved pyrimidine base is one key element of the specific 5' G-C or G-T recognition by the bleomycin-metal complex.
(7) As a basis for the discussion a possible structure for the DNA complex of the phenylated neutral red is considered in which the extra phenyl ring at N-5 of the phenazinium system, protrudes into the large groove of the DNA helix while the tricyclic part of the ligand is inserted between the DNA base-pairs.
(8) A high intensity of the reactions was observed in certain cells of the neural groove in 24-hours' embryos and in the neural tube of 48-hours' embryos.
(9) Recent STM studies of calf thymus DNA and poly(rA).poly(rU) have shown that the helical pitch and periodic alternation of major and minor grooves can be visualized and reliably measured.
(10) In the absence of boxes or grooves, pins markedly enhanced both retention and resistance.
(11) Therefore in artificial knee replacement a lateral tilt of the patella sliding groove should not be propagated as 'physiological'.
(12) Many antitumor drugs, and many carcinogens, act by binding within the minor groove of double-helical DNA, interfering with both replication and transcription.
(13) This instrument, a modification of a corneal trephine, provides a neat, smooth groove of adjustable depth.
(14) and the fluid ejected from the ejaculatory groove region (about 0.2 ml.).
(15) 3) The significance of minor groove Mtase-DNA interactions to specificity is confirmed.
(16) (v) The bis-benzimidazole drug Hoechst-33258, which binds in the minor groove of B-DNA, exhibits very little fluorescence in the presence of the ps hairpins but a normal, enhanced emission with the aps oligonucleotides.
(17) We have studied the time-resolved and the steady-state fluorescence of the DNA groove binders 4',6-diamidino-2-phenylindole (DAPI) and Hoechst 33258 with the double stranded DNAs poly(dA-dU) and poly(dI-dC) and their halogenated analogs, poly(dA-I5dU) and poly(dI-Br5dC).
(18) The complexation-induced chemical shifts and NOE cross peaks in the NOESY map of the 1:1 complex of lexitropsin (1) and d-[CGCAATTGCG]2 reveal that the thiazole ring of the lexitropsin (1) intercalates between dA4.A5 bases and the rest of the ligand resides in the minor groove of the AT rich core of decamer, thus occupying the 5'-AATT sequence on the DNA.
(19) All cases had true hypertelorism and a median nasal groove with absence of the nasal tip.
(20) Distamycin, Hoechst 33258, and DAPI were used as agents capable of AT-specific binding in the minor groove of DNA while producing no profound long-range distortion of DNA structure.