(1) Intravenous infusion of porcine GIP in man induces insulin release when a degree of hyperglycemia is present.
(2) The amylase mRNA was not changed by injection of GIP.
(3) To determine if a similar phenomenon occurs in subjects with non-insulin dependent diabetes mellitus (NIDDM), serum glucose, insulin, C-peptide, and gastric inhibitory polypeptide (GIP) responses to three mixed test meals of varying fatty acid composition were assessed in twelve subjects with NIDDM.
(4) Although structurally related, GIP and glucagon may influence liver blood flow through different mechanisms.
(5) Pancreastatin inhibited carbachol- but not forskolin- or GIP-stimulated insulin release from Rin m 5F cells.
(6) By contrast, the N-terminal portion of GIP can be removed without seriously impairing the activity of the molecule.
(7) In contrast to Gip and G34, labeling of the 46 kDa protein (Gsp) was not influenced by light.
(8) Plasma GIP concentrations were elevated in fed but not fasted streptozotocin diabetic mice, and oral fat evoked a greater GIP response than control mice.
(9) glucose) is reduced in type 2 diabetes although GIP secretion is normal or exaggerated.
(10) The clinical and pathophysiological importance of GIP is discussed by means of various diseases (obesity, maturity-onset diabetes mellitus, duodenal ulcer disease).
(11) The effect of glucose and GIP on insulin release from the isolated perfused pancreas of the same animals was investigated to determine if TPN altered the sensitivity of the beta cell.
(12) Gastric inhibitory polypeptide (GIP) is a gastrointestinal hormone stimulated after oral nutrient ingestion, but not after intravenous nutrient administration.
(13) The GIP was subsequently cleaved from the fusion protein with alpha-thrombin.
(14) Our data indicate that there is a substantial difference in the hemodynamic responses to GIP among splanchnic organs, and suggest that GIP acts specifically on the mesenteric vasculature.
(15) Glucose-dependent insulinotropic polypeptide (GIP) is a forty-two amino acid hormone that stimulates the secretion of insulin from the pancreatic B-cells in the presence of elevated glucose concentrations.
(16) The objective of this study was to compare the gastrin- and gastric inhibitory peptide (GIP)-releasing actions of bombesin, gastrin-releasing peptide (GRP)-27, neuromedin B, and GRP-10 in rats.
(17) The response of GIP to intragastric glucose was not significantly different between pre- and postoperative tests.
(18) We compared the effects of GIP on portal venous and hepatic arterial flow with those of glucagon in conscious dogs.
(19) The basal GIP concentrations were significantly elevated after TV.
(20) At 30 minutes a further increase in IR-GIP to supraphysiologic levels occurred.
Nip
Definition:
(n.) A sip or small draught; esp., a draught of intoxicating liquor; a dram.
(v. t.) To catch and inclose or compress tightly between two surfaces, or points which are brought together or closed; to pinch; to close in upon.
(v. t.) To remove by pinching, biting, or cutting with two meeting edges of anything; to clip.
(v. t.) Hence: To blast, as by frost; to check the growth or vigor of; to destroy.
(v. t.) To vex or pain, as by nipping; hence, to taunt.
(n.) A seizing or closing in upon; a pinching; as, in the northern seas, the nip of masses of ice.
(n.) A pinch with the nails or teeth.
(n.) A small cut, or a cutting off the end.
(n.) A blast; a killing of the ends of plants by frost.
(n.) A biting sarcasm; a taunt.
(n.) A short turn in a rope.
Example Sentences:
(1) Pupils who disrupt the learning of their classmates are dealt with firmly and, in many cases, a short suspension is an effective way of nipping bad behaviour in the bud."
(2) The intravenous hypotensive potency of NIP-121 but not cromakalim was similar to that of p.o.
(3) It is concluded that NIP and IPPV affect the SV RV and the right heart blood flow.
(4) In support of this contention, it was observed that rabbit antiserum to NP-CG, after absorption with CG-Sepharose, augmented the response of mice to standard immunization with NIP(12)-CG.
(5) Mouse spleen B lymphocytes, enriched for cells bearing anti-NIP (hapten 4-hydroxy-3-iodo-5-nitrophenylacetic acid) receptors, were pretreated briefly with NIP-POL (polymerized flagellin) antigen, washed, and added in small numbers to microcultures.
(6) It was shown that to reticular nucleus stimulation responded predominantly those VP and VL neurons (73.7% and 86.2%, respectively) which responded to stimulation of MI and n. NIP.
(7) The arming factor was neutralized by a sufficient concentration of NIP-BSA (twice the concentration causing maximal precipitation) but low concentrations (e.g., 7% of the maximal precipitation concentration) increased the arming capacity.
(8) Zone C has been defined as the cortical region projecting to the nucleus interpositus anterior (NIA) and posterior (NIP).
(9) The medial two-thirds of the nucleus interpositus posterior (NIP) project only to the medial aspect of the NRm, with no apparent organization.
(10) Attention was focussed on B lymphocytes through using hapten human gamma globulin (HGG) preparations as putative tolerogens in tissue culture, the T-cell-independent antigens DNP-POL and NIP-POL as challenge injections in adoptive hosts, and numbers of hapten-specific PFC in host spleens for the quantitation of immune competence.
(11) Retrograde transport of 3H-nipecotic acid (NIP) labeled the myelinated fibers and neurons of the medial OC system, including collateral projections to the peripheral VCN, subpeduncular granule cells, and nucleus Y. Medial and lateral OC efferent collaterals thus innervate different regions of the CN.
(12) Spleen fragments derived from NIP-CG primed mice produced more IgG anti-NIP antibodies than fragments derived from untreated mice when immunized in vitro with NIP-Ficoll.
(13) These activated T cells responded in vitro very well to the NIP-MGG complex but not to the MGG carrier alone demonstrating the requirement of the hapten for T cell stimulation.
(14) These phenotypic and genetic data confirmed that unique Nip+ L. lactis subsp.
(15) Frank Lampard had moved to nip all talk of farewells in the bud.
(16) Lochhead nips in to poke the pass out of the striker's reach.
(17) Complete resolution of NIPS occurred in only two patients, one of whom later developed Parkinson's disease.
(18) These findings suggest that the inverse association between smoking and IPD may apply to NIP.
(19) Jeremy Hunt has it in his secretary of state's power to nip this in the bud and insist that Papworth should realise its move, 10 years in the planning, to the 310-bed hospital in the Cambridge biomedical campus, next door to Addenbrooke's, where Roy Calne pioneered liver transplantation and much more.
(20) She was joint chair of a group of nearly 70 Labour MPs who last summer launched a pro-Europe campaign group, Labour Yes , in a bid to put forward a distinctive leftwing pro-European voice, and nip in the bud any suggestion that Labour support for a referendum represented a cooling of the party’s support for Europe .