(n.) The throat; the gullet; the canal by which food passes to the stomach.
(n.) A narrow passage or entrance
(n.) A defile between mountains.
(n.) The entrance into a bastion or other outwork of a fort; -- usually synonymous with rear. See Illust. of Bastion.
(n.) That which is gorged or swallowed, especially by a hawk or other fowl.
(n.) A filling or choking of a passage or channel by an obstruction; as, an ice gorge in a river.
(n.) A concave molding; a cavetto.
(n.) The groove of a pulley.
(n.) To swallow; especially, to swallow with greediness, or in large mouthfuls or quantities.
(n.) To glut; to fill up to the throat; to satiate.
(v. i.) To eat greedily and to satiety.
Example Sentences:
(1) Denni Karlsson and I are standing by a glacial river as it hammers through a rocky gorge.
(2) Media organisations gorge themselves, then spew out vast quantities of video, sound and copy.
(3) The northern part of the gorge is the only area of Abkhazia that has remained under Georgian government control.
(4) Psychiatric patients have an increased risk for choking compared with the general population because of risk factors such as medication side effects and food gorging.
(5) My plan had read: "Transfer by car from Salta to Purmamarca via the famous tourist attraction of Humahuaca Gorge, then take the bus across the Andes to San Pedro de Atacama in Chile."
(6) No indigenous community will be moved out of their land," he said, adding: "This is a very different project from other major projects, such as the Three Gorges Dam project, which was estimated to have relocated one million people."
(7) You can also enjoy the gorge from the Pine Creek Rail Trail : a 62-mile biking and horseback riding path that runs from the town of Jersey Shore in the south to Stokesdale in the north, passing through the heart of the gorge in the middle.
(8) Let’s begin just after the second world war, when Liverpool took a pre-season trip to the good ol’ US of A to gorge on meat, veg, malted milks and ice creams, working on the theory that by fattening themselves up, they’d have a season’s worth of energy stored when they got back to ration-book Britain.
(9) Each prominent character has been given meaty storylines to gorge on, and while some haven’t panned out quite as well as others (Jimmy’s sideline as a sex worker was introduced and wisely dropped, as was an ill-advised plot-strand about drug-induced rape), the web of intrigue that’s been constructed so far doesn’t have any major weaknesses in it at all.
(10) We propose that binding of acetylcholine, on the surface of AChE, may trigger sequence of conformational changes extending from the peripheral anionic site through W286 to D74, at the entrance of the 'gorge', and down to the catalytic center (through Y341 to F338 and Y337).
(11) In June he and his team were looking at the steep hillsides around the village of Glogova, where remains had been tipped out of trucks and allowed to roll down a gorge.
(12) These data indicate a species difference exists between rats and mice during adaptation to a gorging food-intake pattern.
(13) Facebook Twitter Pinterest Aerial view of the Three Gorges dam on the Yangtze river, the biggest such project on earth.
(14) TonyRidge Strid Wood, Bolton Abbey, North Yorkshire Exploring the woodland at either side of the River Wharfe, where it flows through this spectacular, narrow gorge, is a splendid experience at any time of the year.
(15) In the knowledge that some of the biggest countries in world football – and some of the richest – were queueing up to host the 2018 and 2022 tournaments, football administrators around the world who had long gorged on the flow of Fifa cash were gearing up for a major payday.
(16) If he had been able to cross gorges and rivers without the need for ancient Egyptian conceits or even unadorned iron trusses, I think he would have leaped at the chance.
(17) As the trucks arrived at the edge of the gorge and tilted their beds back, Abu Abdullah watched in horror as the corpses of women and children began tumbling out.
(18) We want Squeaky Bum Time all the time - and if we don't get it we're going to sit howling in front of our flat-screen televisions, gorging ourselves on scratch cards, KFC popcorn chicken, superficial friendships, crack, two-minute microwave porridge and Ronseal super-quick-drying wood stain.
(19) A new partial skeleton of an adult hominid from lower Bed I (about 1.8 Myr ago), Olduvai Gorge, is described.
(20) Most of them scale Dome Rock, a big exfoliated granite monolith that offers 360-degree views of the mountain range, from the aforementioned Mount Whitney to the north to the Kern gorge (famous for its whitewater rafting) to the south.
Groove
Definition:
(n.) A furrow, channel, or long hollow, such as may be formed by cutting, molding, grinding, the wearing force of flowing water, or constant travel; a depressed way; a worn path; a rut.
(n.) Hence: The habitual course of life, work, or affairs; fixed routine.
(n.) A shaft or excavation.
(v. t.) To cut a groove or channel in; to form into channels or grooves; to furrow.
Example Sentences:
(1) The ligands bind at discrete sites in the minor groove of DNA, and analysis on DNA sequencing gels show pronounced protection at the ligand binding sites, as well as more generalized protection.
(2) Recent reports have indicated the usefulness of nuclear grooves (clefts or notches) as an additional criterion for the diagnosis of papillary thyroid carcinoma in fine needle aspirates; most of these studies were carried out on alcohol-fixed material stained with the Papanicolaou stain or with hematoxylin and eosin, which yield good nuclear details.
(3) Intermolecular contacts occur in both oligomers in the minor groove: in the B form through twisted guanine-guanine hydrogen bonding, and in the Z form through base-base stacking and the water network.
(4) The nogalose and aminoglucose sugars lie in the minor and major grooves, respectively, of the distorted B-DNA double helix.
(5) The AFB1 moiety is face-stacked in the major groove with its long axis approximately perpendicular to the helix axis.
(6) These results strongly indicate that metallobleomycin binds in the minor groove of B-DNA and that the 2-amino group of guanine adjacent to the 5' side of the cleaved pyrimidine base is one key element of the specific 5' G-C or G-T recognition by the bleomycin-metal complex.
(7) As a basis for the discussion a possible structure for the DNA complex of the phenylated neutral red is considered in which the extra phenyl ring at N-5 of the phenazinium system, protrudes into the large groove of the DNA helix while the tricyclic part of the ligand is inserted between the DNA base-pairs.
(8) A high intensity of the reactions was observed in certain cells of the neural groove in 24-hours' embryos and in the neural tube of 48-hours' embryos.
(9) Recent STM studies of calf thymus DNA and poly(rA).poly(rU) have shown that the helical pitch and periodic alternation of major and minor grooves can be visualized and reliably measured.
(10) In the absence of boxes or grooves, pins markedly enhanced both retention and resistance.
(11) Therefore in artificial knee replacement a lateral tilt of the patella sliding groove should not be propagated as 'physiological'.
(12) Many antitumor drugs, and many carcinogens, act by binding within the minor groove of double-helical DNA, interfering with both replication and transcription.
(13) This instrument, a modification of a corneal trephine, provides a neat, smooth groove of adjustable depth.
(14) and the fluid ejected from the ejaculatory groove region (about 0.2 ml.).
(15) 3) The significance of minor groove Mtase-DNA interactions to specificity is confirmed.
(16) (v) The bis-benzimidazole drug Hoechst-33258, which binds in the minor groove of B-DNA, exhibits very little fluorescence in the presence of the ps hairpins but a normal, enhanced emission with the aps oligonucleotides.
(17) We have studied the time-resolved and the steady-state fluorescence of the DNA groove binders 4',6-diamidino-2-phenylindole (DAPI) and Hoechst 33258 with the double stranded DNAs poly(dA-dU) and poly(dI-dC) and their halogenated analogs, poly(dA-I5dU) and poly(dI-Br5dC).
(18) The complexation-induced chemical shifts and NOE cross peaks in the NOESY map of the 1:1 complex of lexitropsin (1) and d-[CGCAATTGCG]2 reveal that the thiazole ring of the lexitropsin (1) intercalates between dA4.A5 bases and the rest of the ligand resides in the minor groove of the AT rich core of decamer, thus occupying the 5'-AATT sequence on the DNA.
(19) All cases had true hypertelorism and a median nasal groove with absence of the nasal tip.
(20) Distamycin, Hoechst 33258, and DAPI were used as agents capable of AT-specific binding in the minor groove of DNA while producing no profound long-range distortion of DNA structure.