(a.) Consisting of, or resembling, grains; as, a granular substance.
Example Sentences:
(1) The leukemic T-cells in two patients with chronic lymphocytic leukemia (CLL) had specific features of large granular lymphocytes (LGL), and those in two patients with acute lymphocytic leukemia (ALL) had L2 morphologic characteristics.
(2) Combined SEM and TEM examination of the endothelium of compressed segments revealed "craters" and "balloons", blebs and vacuoles, swollen mitochondria, dilated granular endoplasmic reticulum, and subendothelial edema.
(3) In situ hybridization of SMG sections showed that Aeg-1 and Aeg-2 transcripts are produced by the cells of granular convoluted tubules.
(4) In the terminal segment of the hamster epididymidis there was some evidence of micro-merocrine protein secretion a the level of the principal cells and clear evidence of granular secretion in the light cells, presumable of glycoproteins.
(5) Measurable quantities of temefos were found in the snails within 1 day after the first treatment with a 2% granular formulation but 3 weeks elapsed before uptake occurred following treatment with a temefos emulsion.
(6) Electron microscopic examination of all leptomeningeal and meningioma cultures revealed desmosomes and dense tonofilament formation; in addition, granular, filamentous basement membrane-like material was abundant in the extracellular spaces of all cultures.
(7) Cholecystokinin (CCK) as the sulfated (CCK-8S) and unsulfated (CCK-8U) octapeptide sequences, and CR 1409 were administered intraventricularly while the action potential (EAP) in the granular cell layer of the hippocampal dentate gyrus evoked by perforant path stimulation was recorded.
(8) The granules of human large granular lymphocytes have been reported to contain, in addition to perforin, a soluble HRF activity that can be eluted from anion-exchange columns at 115 mM NaCl.
(9) Moreover, it was more apparent in less differentiated tumors in which the granular pattern was often absent or inconsistent.
(10) Ultrastructural examination of noncartilaginous regions of the tumor demonstrated mesenchymal cells with features suggestive of cartilaginous differentiation, viz, scalloped cell membranes, sac-like distension of abundant rough endoplasmic reticulum, and a matrix containing fibrillary and finely granular material.
(11) As cyclic AMP-stimulated water flow and sodium transport are thought to occur in one cell type, the granular cells, distinct pools of cyclic AMP are thought to be present in one and the same cell type.
(12) The data obtained testify to the presence in the granular fraction of the endopeptidase LTH-converting activity which is sensitive to pepstatin A, an aspartyl proteinase inhibitor as well as to chelators and a serine proteinase inhibitor.
(13) In the advanced papilloma, cytolytic cells in the outer spinous and the granular layers did not stain positively with any of the three antibodies used.
(14) During the latest phase the periequatorial material is vanishing, the hyaloid capillaries disappear, the density of the posterior granular substance decreases.
(15) Culturing mononuclear cells from peripheral blood or bone marrow of leukemia patients with IL-2 resulted in an expansion of residual large granular lymphocytes and development of cytotoxic activity.
(16) The ultrastructural study of nucleoli and ribonucleoprotein-containing structures in human seminiferous tubules revealed that the nucleoli of spermatogonia, spermatocytes and Sertoli cells exhibited a tripartite structure consisting of: a fibrillar center, a compact granular portion, and a reticular portion containing both pars fibrosa and pars granulosa.
(17) This technique contrasted the fibrillar component and the granular component in interphase nucleoli as a reflection of the degree of packing.
(18) An enormous occurrence of granular endoplasmic reticulum in the intestinal cells of P. commutatus shows an excessive protein synthesis.
(19) Large aggregates of finely granular or filamentous material (nematosomes) were present in AD neurons.
(20) After incubation of cells in a fresh medium (in the course of 18, 24 hours) there occurs a total restoration of the ultrastructure of the nuclei, granular endoplasmatic reticulum, mitochondria, due to the repairing and strong intensification of synthetic processes, respiration and glycolysis, mitotic activity of the cells.
Gritty
Definition:
(a.) Containing sand or grit; consisting of grit; caused by grit; full of hard particles.
(a.) Spirited; resolute; unyielding.
Example Sentences:
(1) Given his background, Boyle says, growing up in a council house near Bury, with his two sisters (one a twin) and his strict and hard-working parents (his mum worked as a dinner lady at his school), he should by rights have been a gritty social realist, but that tradition never appealed to him.
(2) San Francisco Tenderloin map They could potentially gentrify this gritty, 50-block swath of downtown into condos, lofts, hipster bars, organic cafes and yoga studios, as has happened in other parts of San Francisco and the Bay area.
(3) Concluding that he didn't really want a career as a gritty Northern Irish realist, Harvey decided to train as a teacher.
(4) Sitting in the bar at the Lowry theatre in Salford’s Media City, Shindler is talking about the word “gritty”.
(5) Click here to view video This year has been all about exciting gritty modern TV dramas.
(6) A gritty town battered by the decline of its lumber industry, it is mocked as hicksville by its rival, snootier neighbour, the university city Eugene, which Groening renamed Shelbyville.
(7) It manages to be both hard-hitting and emotional, gritty and warm."
(8) The chief executive is pinning early hopes on Breaking Bad, a gritty US drama in which a chemistry teacher with terminal cancer sets up a crystal meth lab, which was barely noticed when it aired on 5USA, although for all its merits it might not exactly be classified as family entertainment.
(9) Yet there is a tendency to switch off from this conversation as it moves from ambitious words and statements on to the nitty gritty of implementation.
(10) Bellows is known for his powerful paintings representing the hardship and desperation and grittiness of life in New York as it emerged in to the 20th century.
(11) "There is plenty of gritty contemporary life on the wrong side of the tracks, but there is also a ridiculous story of revenge.
(12) The chondroblastoma was located in a small gritty mass at one pole of the cyst, which could have easily been overlooked.
(13) That’s a difficult exercise, particularly with all the lawyers involved in the process and looking at the nitty-gritty of every word that is written down,” Zarif told journalists during a visit to Madrid.
(14) Fifteen years ago, the flag was the subject of a gritty partisan struggle in the state house and an economic boycott by the NAACP.
(15) Symptoms of grittiness and morning stickiness were more frequent among patients without enhanced responses.
(16) Prey is a gritty, concretey number, and while Reinhardt may be the least-kempt of the cast, every character drinks too much, looks constantly knackered and is therefore entirely believable.
(17) Of 440 amputations for vascular disease, 193 were above-knee, 193 below-knee, 15 Gritti-Stokes, 15 through-knee and 24 bilateral.
(18) In her day this was a gritty neighbourhood and it hasn’t changed much, with a shabby market by the metro station and blocks of peeling townhouses; this is the real, old Paris, the world she sang about, with its desperate cast of thieves and tramps and lovers.
(19) "That kind of geographic splitting can certainly create opportunities for speciation, so it's a plausible mechanism, but I'd like to see a more extensive and fine-grained review of the evidence than Mark and his coauthors could cram into their paper – one that gets into the nitty-gritty of where the basins were, when the marine barriers between them would have appeared and disappeared, and what lived in them."
(20) Fishwick's layer upon layer of northern grittiness versus southern sniffiness will be grating for some.