(1) The patterns observed were: clusters of granules related to the cell membrane; positive staining localized to portions of the cell membrane, and, less commonly, the whole cell circumference.
(2) The extrusion of granules into the intercellular space via exocytosis is frequently observed.
(3) We have previously shown that serotonin is present in secretory granules of frog adrenochromaffin cells; concurrently, we have demonstrated that serotonin is a potent stimulator of corticosterone and aldosterone secretion by adrenocortical cells.
(4) Finally, it could be observed that elevated osmotic pressures reduced the lysis of isolated secretory granules when bicarbonate ions were present in the incubation medium.
(5) In addition, transitional macrophages with both positive granules and positive RER, nuclear envelope, negative Golgi apparatus (as in exudate- resident macrophages in vivo), and mature macrophages with peroxidatic activity only in the RER and nuclear envelope (as in resident macrophages in vivo) were found.
(6) They had no endocrine-like granules and were not associated with nerves or basement membranes.
(7) Electron microscopic immunohistochemistry revealed histamine-immunostaining in granules in a small number of nerve fibers and varicosities.
(8) Results of detailed studies on tissue reactions to Cysticercus bovis in the heart of cattle, together with a comparison of findings in animals with spontaneous and experimental infection, and an evaluation of tissue reactions in relation to the location, morphology and morphogenesis of C. bovis provided evidence for the fact that in general, the response of the heart to the presence of C. bovis was an inflammatory reaction characterized by the origin of a pseudoepithelial border and a zone of granulation tissue.
(9) The presence of a previously unreported dipeptide transport mechanism within blood leukocytes and the selective enrichment of the granule enzyme, DPPI, within cytotoxic effector cells of lymphoid or myeloid lineage appear to afford a unique mechanism for the targeting of immunotherapeutic reagents composed of simple dipeptide esters or amides.
(10) The volume density of glycogen granules in hepatocytes was highest 4 hr after the secretory granules of B cells showed the lowest value.
(11) A new technique to obliterate the mastoid volume or to reduce an old cavity by means of hydroxyapatite granulate is presented.
(12) The data suggest that proinsulin, normally processed in secretory granules and released via the regulated pathway, may also be processed, albeit less efficiently, by the constitutive pathway conversion machinery.
(13) In telecost fishes, the corpuscles of Stannius contain Bowie-stainable granules and a renin-like pressor substance.
(14) Electron microscopy revealed a well-developed rough endoplasmic reticulum, an enlarged Golgi apparatus and many highly electron-dense secretory granules resembling those of Clara cells.
(15) The study confirms that secretin influences pancreatic protein secretion and indicates in addition, that pharmacologic doses of the hormone, have the capacity to block acinar cell zymogen granule release.
(16) Immunoreactions of LTR which were seen in specific granules of neutrophils and monocytes attached to the endothelial cell surface may indicate the onset of endothelial cell damage.
(17) The capacity of granule-cell networks to separate overlapping patterns of activity on their inputs is adequate, with spatial variability in the secretion at synapses, but is improved if there is also temporal variability in the stochastic secretion at individual synapses, although this is at the expense of reliability in the network.
(18) These results suggest that bPAG is probably synthesized by trophoblast binucleate cells and stored in granules prior to delivery into the maternal circulation after cell migration.
(19) CAM, especially CD11c, were also detected in cytoplasmic granules by immunostaining in IL2-activated NK cells.
(20) The outstanding morphologic feature of cortical cells exposed to microunit ACTH concentrations for 40 min was the abundance of electron-dense granules (0.2-0.4 mum).
Pinch
Definition:
(v. t.) To press hard or squeeze between the ends of the fingers, between teeth or claws, or between the jaws of an instrument; to squeeze or compress, as between any two hard bodies.
(v. t.) o seize; to grip; to bite; -- said of animals.
(v. t.) To plait.
(v. t.) Figuratively: To cramp; to straiten; to oppress; to starve; to distress; as, to be pinched for money.
(v. t.) To move, as a railroad car, by prying the wheels with a pinch. See Pinch, n., 4.
(v. i.) To act with pressing force; to compress; to squeeze; as, the shoe pinches.
(v. i.) To take hold; to grip, as a dog does.
(v. i.) To spare; to be niggardly; to be covetous.
(n.) A close compression, as with the ends of the fingers, or with an instrument; a nip.
(n.) As much as may be taken between the finger and thumb; any very small quantity; as, a pinch of snuff.
(n.) Pian; pang.
(n.) A lever having a projection at one end, acting as a fulcrum, -- used chiefly to roll heavy wheels, etc. Called also pinch bar.
Example Sentences:
(1) produced a strong analgesic effect in the formalin test and in the tail pinch test.
(2) The observed clinical findings include scarring of the face and hands (83.7%), hyperpigmentation (65%), hypertrichosis (44.8%), pinched facies (40.1%), painless arthritis (70.2%), small hands (66.6%), sensory shading (60.6%), myotonia (37.9%), cogwheeling (41.9%), enlarged thyroid (34.9%), and enlarged liver (4.8%).
(3) Results indicate substantial postoperative improvement in tip prehension and grasp, while performance remained essentially unchanged for lateral prehension, pinch force, and power grip.
(4) To mimic physiological conditions, synaptosomes, which are pinched off presynaptic nerve termini, were used.
(5) Comparison with other pinch strength studies established that although force magnitudes may be strongly influenced by specific experimental conditions, empirical relationships among different pinch forces are fairly stable and predictable.
(6) Anyone still imagining that it was only the defender’s recovery from injury rather than his form that was preventing him from starting (and it’s been clear for a while that’s not the case) might have noted the coach’s instructions to Gonzalez to be ready to play a few minutes when needed, either as an extra defender or even in a pinch as an extra forward.
(7) He has just performed a skit now about his bicycle scheme, which included a swipe at the French (because their scheme resulted in many more cycles being pinched, apparently.)
(8) Other small endocytic vesicles pinch off from the surface, move deeper into the cytoplasm and fuse with the lateral plasmalemma; their protein content is emptied into the intercellular space by exocytosis.
(9) It is suggested that the optimal way to diagnose microsporidiosis is by light microscopical examination of duodenal pinch biopsy specimens.
(10) Numerous 70-mmicro diameter vesicles apparently pinch off from the Golgi systems, transport this material through the egg, and probably then fuse to form a crenate, membrane-limited yolk droplet.
(11) Analysis of the rate of functional recovery as measured by total active motion, gross grip strength, and pinch grip strength showed no significant difference between the two groups.
(12) Which is another reason why, independent of talent, an Argentine is more likely to make a successful go of life in Madrid, Milan, Manchester or at a pinch (as with the case of the winger Carlos Marinelli) Middlesbrough.
(13) The term "barons" hasn't really had any meaning since the Combination Act of 1799 ; at a pinch 1825 , when the legislation to prevent the activity of unions was passed again, in the Combination of Workmen Act.
(14) A temporary pinching off of the spermatic cord was carried out in 100 male Wistar rats in order to evaluate the effect of a limited period of ischaemia on the testicular parenchyma.
(15) It involved bringing in Kyle Beckerman alongside Jermaine Jones in the base of midfield and asking Jones to pinch in when necessary and get forward when possible.
(16) Neurons were first classified as on-cells if they fired faster during noxious pinch or as off-cells if they fired slower.
(17) The pinch technique has been found to be useful in repairing cosmetic eyelid deformities.
(18) It is proposed that pinch-induced immobility is mediated by both dopaminergic and cholinergic systems.
(19) In this article the concept of utilizing a pinched inlet channel for field-flow fractionation (FFF), in which the channel thickness is reduced over a substantial inlet segment to reduce relaxation effects and avoid stopflow, is evaluated for steric FFF using one conventional channel and two pinched inlet channels.
(20) Pharmacological analysis of the involvement of the brain catecholamines in tail-pinch behavior suggests that it is critically dependent on the nigrostriatal dopamine system.