(v. t.) To clean, as a vessel's bottom, of barnacles, grass, etc., and pay it over with pitch; -- so called because graves or greaves was formerly used for this purpose.
(superl.) Of great weight; heavy; ponderous.
(superl.) Of importance; momentous; weighty; influential; sedate; serious; -- said of character, relations, etc.; as, grave deportment, character, influence, etc.
(superl.) Not light or gay; solemn; sober; plain; as, a grave color; a grave face.
(superl.) Not acute or sharp; low; deep; -- said of sound; as, a grave note or key.
(superl.) Slow and solemn in movement.
(n.) To dig. [Obs.] Chaucer.
(n.) To carve or cut, as letters or figures, on some hard substance; to engrave.
(n.) To carve out or give shape to, by cutting with a chisel; to sculpture; as, to grave an image.
(n.) To impress deeply (on the mind); to fix indelibly.
(n.) To entomb; to bury.
(v. i.) To write or delineate on hard substances, by means of incised lines; to practice engraving.
(n.) An excavation in the earth as a place of burial; also, any place of interment; a tomb; a sepulcher. Hence: Death; destruction.
Example Sentences:
(1) A reduction in neonatal deaths from this cause might be expected if facilities for antenatal diagnosis and termination of pregnancy were made available, although this raises grave ethical problems.
(2) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
(3) A patient with previously treated follicular carcinoma of the thyroid developed Graves' disease with a high titre of thyroid-stimulating antibodies (TSAb).
(4) Gwendolen Morgan, the lawyer at Bindmans dealing with the case, said: "We have grave concerns about the decision to use this draconian power to detain our client for nine hours on Sunday – for what appear to be highly questionable motives, which we will be asking the high court to consider.
(5) Superoxide dismutase (SOD) activity and its concentration were measured in thyroid tissues obtained from patients with Graves' disease, Hashimoto's thyroiditis, differentiated thyroid cancer, and endemic goiter (before and after iodine supplementation) as well as in normal thyroid tissue (paranodular tissue) from patients with follicular adenomas.
(6) Many reports of thyroid stimulating immunoglobulins (TSI) in relation to treatment of Graves' disease have been published and with variable results concerning prediction of permanent remission or relapse after therapy.
(7) The Duke and Duchess of Cambridge stood among the graves on 4 August last year in a moving ceremony to mark the 100th anniversary of the outbreak of war.
(8) After violence had run its bloody course, the country’s rulers conceded it had been a catastrophe that had brought nothing but “grave disorder, damage and retrogression”.
(9) On the other hand, immunofluorescence in anterior pituitary cells was faint and detected in only 2 of 28 patients with Graves' disease (7.1%) after absorption of their sera with rat liver aceton powder.
(10) In conclusion, not only TBII but also T3 release-stimulating antibodies may occur in a minority of patients with long-term remission of Graves' hyperthyroidism.
(11) It is deeply moving hearing him talk now – as if from the grave – about a Christmas Day when he felt so frustrated and cut-off from his family that he had to go into the office to escape.
(12) His verdict of her that "she danced on the graves of her husband's victims.
(13) Thirty-eight bodies have been removed from the mass graves, but DNA tests have shown that none is that of a missing student.
(14) Posterior synechiae, pupil deformations, grave uveitis with hypotonia of 4-10 mm Hg are rapidly developing.
(15) Displacement of [125I]TSH bound to fat cell membranes by both Graves' Ig and unlabeled TSH were time and temperature dependent, with similar dissociation curves, suggesting a specific binding of Graves' Ig to the membrane sites related to the TSH receptor in the fat cells.
(16) We have obtained sera from 42 patients with active Graves' disease and no known connective tissue disorders.
(17) A total of 5.8% abnormalities were found including nodular disease, thyroiditis, Graves' disease, hypothyroidism, simple goiter, and iatrogenic hyperthyroidism.
(18) LATS was measured with the double isotope technique in IgG serum concentrates of 23 patients with Graves' disease before treatment and of 18 patients during treatment with carbimazole and triiodothyronine.
(19) To elucidate whether insulin-induced hypoglycemia enhances the release of beta-endorphin in man, plasma extracts obtained from healthy subjects and patients with Graves' disease before and 45 min after insulin injection were subjected to gel chromatography, and the fractions obtained were measured by RIA for beta-endorphin.
(20) From the findings of abnormalities in intrathyroidal T cell subsets, we suggest that the decrease in the function of suppressor T cells within the thyroids of Graves' disease patients may be due to a decrease in CD4+2H4+ cells within thyroid tissue.
Sober
Definition:
(superl.) Temperate in the use of spirituous liquors; habitually temperate; as, a sober man.
(superl.) Not intoxicated or excited by spirituous liquors; as, the sot may at times be sober.
(superl.) Not mad or insane; not wild, visionary, or heated with passion; exercising cool, dispassionate reason; self-controlled; self-possessed.
(superl.) Not proceeding from, or attended with, passion; calm; as, sober judgment; a man in his sober senses.
(superl.) Serious or subdued in demeanor, habit, appearance, or color; solemn; grave; sedate.
(v. t.) To make sober.
(v. i.) To become sober; -- often with down.
Example Sentences:
(1) It's typically sober and elegant, and Cotillard excels in a nervy, vulnerable role.
(2) Read Rachel’s full story Facebook Twitter Pinterest Chris Owen: ‘I’ve been sober for six years now, and I don’t miss alcohol.’ Photograph: Graeme Robertson for the Guardian I spent my 20s playing Russian roulette with alcohol The NHS has been there time and time again for Chris Owen, who battled alcoholism throughout his 20s.
(3) Anthony Wells, director of YouGov’s political and social research team, said: “While there will be speculation about whether this movement is connected to the tragic death of Jo Cox, we do not think that it is... We are now in the final week of the referendum campaign and the swing back towards the status quo appears to be in full force.” EU referendum voters unconvinced by scare tactics: ‘I just want to do what’s right’ Read more Today, both sides will resume their battle to capture the votes of the undecided and to persuade people to switch sides, though both the Leave and Remain camps say that the manner of their campaigning will be more sober and less combative.
(4) Previous research has found a relationship between increased quantity of alcohol usually consumed per drinking occasion and decreased sober cognitive performance.
(5) "Yet the sobering fact remains that a transition to a low-carbon, inclusive green economy is happening far too slowly and the opportunity for meeting the 44 gigatonne target is narrowing annually," Steiner said.
(6) The haemostatic imbalance normalizes within two or three weeks of soberness while the immune system requires about two months to recover.
(7) Chambers claims she became extremely intoxicated while her ex-boyfriend remained much more sober, and says she has no memory of him having sex with her that night.
(8) Therefore, the presence of pulmonary emboli in association with sagittal sinus thrombosis mandates a sober assessment of the need of anticoagulation therapy in the absence of obvious contraindication.
(9) Mutual intoxication was a feature in 44% of the cases and in 34% both participants were sober.
(10) Impulsive and bonhomous, Saakashvili, meanwhile, is clearly the temperamental opposite of Putin, the sober and clinical former KGB colonel.
(11) Barton rubs Old Firm up the wrong way Joey Barton apologises ‘unreservedly’ after being sent home by Rangers Read more The phrase “Joey Barton Twitter storm” is pretty much a tautology, so it was no surprise that his decision to sign for Rangers in May had social media in a kerfuffle when his 2012 tweet – “I am a Celtic fan” – was dredged up so that it might be subject to calm and sober scrutiny from all concerned.
(12) And yet here I am today, a sober, emancipated, successful and happy woman.
(13) After all, on any sober calculation of relative sins, HSBC's dealings with Mexican drug bandits were surely several leagues more serious than other banks' Libor-rigging scandals.
(14) In the swinging 1960s, Peck's sober style seemed a little out of place, though he appeared in a couple of flashy Hitchcockian thrillers, Mirage (1965) and Arabesque (1966), and adapted to the new Hollywood as best he could, looking rather bothered as the father of a demon in The Omen (1976).
(15) Alcoholics reported more anger and aggression when drinking than when sober and this effect was greatest among individuals with a history of childhood aggression.
(16) She observed soberly that "the moment human beings lacked their own government and had to fall back upon their minimum rights, no authority was left to protect them and no institution was willing to guarantee them … Loss of national rights was identical with loss of human rights … The rights of man, supposedly inalienable, proved to be unenforceable … whenever people appeared who were no longer citizens of any sovereign state."
(17) It's not the most groundbreaking piece of research, but I did find it both instructive and sobering.
(18) In a year that will be punctuated by sober reflection and a series of commemorative occasions, it is tempting to assume a certain inevitability to events, especially when looking at them through the prism of hindsight.
(19) Even in alcoholics who have been sober for a long time, increased cardiac output is very common and these changes are similar to those seen in some patients with labile hypertension.
(20) He was a vegan, sober, nonsexual God-botherer partying in the blood-soaked Meatpacking District with the sex-and-druggers.