(1) The data were grouped to determine differences between the experimental and the newly revised formats of the GRE-A measure, in addition to any differences among programs.
(2) However, a purified recombinant fragment of the GR which contained essentially only its DNA binding domain was unable to bind at the GME although it interacted strongly with a consensus GRE sequence.
(3) Although GRE images rapidly demonstrated flow in vascular intracranial lesions as high intensity, the vascular nature of these lesions was also clearly evident on SE images in most cases.
(4) We have used cloned rat glucocorticoid-receptor coding sequences to produce and characterize a novel class of receptor mutants that elicit GRE enhancer function in transfected cells even in the absence of hormone.
(5) The MR appearance of thrombosis of the portal vein and its branches using gradient echo (GRE) sequences is described.
(6) Assuming that function as a GRE reflects binding of glucocorticoid receptor, our activity data are consistent with the recognition of the GRE as two hexamer half-sites, each half-site recognized by a single subunit of a receptor dimer, probably in a cooperative fashion.
(7) The sequence recognition by the glucocorticoid receptor at the different defined glucocorticoid regulatory elements (GRE) is discussed and a consensus sequence formulated.
(8) We found that the promoter is extremely G + C rich (72% GC content) and contains a "TAATA" and a "CAT" box, eight "GGGCGG", three "CCGCCC" and two "CACCC" motifs and a motif similar to the glucocorticoid responsive element (GRE) which included two interchanged nucleotides "TCTTGT".
(9) Gel retardation analysis demonstrates that bacterially expressed c-Jun disrupts GR-GRE complexes.
(10) These results demonstrate the importance of GRE consensus sequences in glucocorticoid receptor interactions with DNA, and further identify a cause for high background binding observed when pBR322 DNA is used as a negative control in studies of glucocorticoid receptor-DNA interactions.
(11) Given the "time of flight" effect of GRE sequences, a scan plane perpendicular to the direction of flow was used to obtain maximal signal enhancement of flowing blood.
(12) All pRagCAT constructs in which the 5'-region contained at least one of the two GRE consensus sequences were stimulated by dexamethasone.
(13) Oversaturation (2.0 mumol Fe for SE sequences, greater than or equal to 1.0 mumol Fe for GRE sequences) led to image distortion and did not allow assessment of lymph node morphology.
(14) To accommodate the observed biphasic dose-response curve for highly specific glucocorticoids, and the shift-to-the-left for both classes of effector, we have proposed a model of a single "turn-on" nuclear acceptor site for glucocorticoid receptors (glucocorticoid regulatory element: GRE) and multiple, pre-emptive "turn-off" GREs, occupancy of any one of which will abrogate transcription; for progestins, we propose that all the GRE are alternate "turn-off" sites.
(15) A moderately repetitive DNA sequence, containing a TATA box, a GRE consensus, a Z-DNA forming sequence and two imperfect direct repeats at the extremities, is present a few nucleotides 5' of the human PAI-1 gene transcription start site, raising the possibility that this gene could have been activated by DNA insertion during evolution.
(16) In vitro transcription experiments using a Xenopus laevis cell-free extract have demonstrated that a DNA fragment containing a glucocorticoid response element (GRE) significantly enhances the expression of a methionine tRNA gene.
(17) R1881-activated transcription of a GRE-tk-CAT reporter gene construct was strongly diminished by both mutant receptors and was only partially restored using a 100-fold higher concentration of ligand compared with wild-type receptor.
(18) New cine GRE imaging techniques provide a noninvasive means for quantification of valvular as well as ventricular function.
(19) To investigate the detection of vascular extension of tumor with the GRE technique, findings in the preoperative GRE MR images of 26 patients with renal adenocarcinoma were compared with findings at surgery and pathologic examination.
(20) Our results demonstrate that in-plane GRE imaging and MR angiography can potentially be used as noninvasive methods for evaluating vascular patency in the presence of MR-compatible endovascular devices.
Gyre
Definition:
(n.) A circular motion, or a circle described by a moving body; a turn or revolution; a circuit.
(v. t. & i.) To turn round; to gyrate.
Example Sentences:
(1) The plastic - most of it swept from coastal cities in Asia and California - is trapped indefinitely in the region by the North Pacific Gyre, a vortex of currents that circulate clockwise around the ocean.
(2) It is not news that microplastic – which the National Oceanic and Atmospheric Administration defines as plastic fragments 5mm or smaller – is ubiquitous in all five major ocean gyres .
(3) These end-to-end contacts were observed in every second gyre on the four lines surrounding the core of the axoneme at stage 3.
(4) Several sites link to the original text that accompanied the photograph when it was first used three years ago, in an online journal of the Beaufort Gyre Exploration Project, in which the ice block is described as 'extraordinary'.
(5) Possible extensions of density between the gyres have been located, but these are below the significance level of the electron density map.
(6) Fortunately, Merkl said the issue is starting to rise up the political agenda, helped by the sight of giant gyres of marine debris and by people from the developed world going on beach holidays and finding plastics clinging to their bodies.
(7) Multilamellar sheets consisted of as many as 10 or 12 closely spaced gyres.
(8) The expedition was a joint effort between three non-profit groups: Eriksen's 5 Gyres Institute, the Algalita Foundation, and the Ocean Voyage Institute.
(9) These include Algalita Marine Research Foundation (founded by captain Charles Moore, who first raised the issue of microplastics in oceans), 5 Gyres, and Adventurers and Scientists for Conservation (ASC), with whom Abigail Barrows works to collect surface water samples from around the world for her research into microfibers.
(10) Most of the histone core is contained within the inner surface of the superhelical DNA, except for part of H2A which extends between the DNA gyres near the terminus of the DNA.
(11) As seen by scanning electron microscopy, the mitochondrial helix in the developing midpiece of mouse testicular spermatozoa is dextral in direction and consists of spherical mitochondrial units arranged in an orderly array of four units per gyre: three appearing in face view and a fourth hidden from view at the back of the gyre.
(12) Mitochondria further elongated and end-on touching appeared with every third gyre on the five longitudinal lines that surround the core of the axoneme (stage 4).
(13) A similar extension of a portion of histone H4 between the DNA gyres occurs close to the dyad axis.
(14) First and most surprising, the prominent coiling of the chromosomes is strongly chiral, with right-handed gyres predominating.
(15) Much of this rubbish accumulates in large ocean gyres, which are circular currents that collect plastics in a particular area.
(16) The center-to-center distance of each gyre is approximately 650 A, and the hollow structures are ca.
(17) With a change in microtubular array, the ridge surface of the nuclear helix becomes flattened and depressed; the gyres of the nuclear helix increase in number.
(18) During helical shaping of the acrosome, the microtubule bundle is closely associated with the posterior one gyre of the acrosomal helix with the same pitch as in the nuclear helix.
(19) We test nonsense when we could "gyre and gimble in the wabe".
(20) The boundary between successive gyres of the subfiber are obscured at the completion of condensation resulting in the formation of a homogenous 250- to 300-nm fiber that is the native centromere.