(v. t.) To look upon with desire to possess or to appropriate; to envy (one) the possession of; to begrudge; to covet; to give with reluctance; to desire to get back again; -- followed by the direct object only, or by both the direct and indirect objects.
(v. t.) To hold or harbor with malicioua disposition or purpose; to cherish enviously.
(v. i.) To be covetous or envious; to show discontent; to murmur; to complain; to repine; to be unwilling or reluctant.
(v. i.) To feel compunction or grief.
(n.) Sullen malice or malevolence; cherished malice, enmity, or dislike; ill will; an old cause of hatred or quarrel.
(n.) Slight symptom of disease.
Example Sentences:
(1) Trawling through the private telephone conversations of royals, politicians and celebrities in the hope of picking up scandalous gossip is not seen as legitimate news gathering and the techniques of entrapment which led to the recent Pakistani match-fixing scandal , although grudgingly admired in this particular case, are derided as manufacturing the news.
(2) Governor Phil Bryant only offered a grudging acceptance of the order, saying the court had overreached into states’ rights and was “certainly out of step with the majority of Mississippians”.
(3) The praise from supporters of other clubs and some commentators was grudging and qualified.
(4) Consider their peerless dead parrot sketch which, in many people's memories, ends when Cleese does his huge rant, and Palin grudgingly offers to replace the bird.
(5) On a personal level, no one could grudge Snodgrass his hat-trick in Malta after the kneecap injury that earlier disrupted his career and international journey.
(6) The doomsday scenario privately discussed at both party conferences so far was the grudging election of a largest party of whichever flavour, but without the majority or mandate to fight its way out of a paper bag.
(7) Lance Armstrong held the meanest grudges in cycling, in effect ruining the career of Christophe Bassons after the French rider dared to talk publicly about doping.
(8) It's a belated recognition of this verdict that has spurred a new debate on the centre-right, with pragmatists from influential skills minister Matthew Hancock to key players at the Daily Telegraph moving beyond grudging acceptance of the existence of the minimum wage to making a more full-throated case for strengthening it.
(9) I feel that if this doesn't happen this situation will lead to discord and grudge."
(10) The view of most people I've talked to is that he's improved the paper and there is a grudging respect for what he's done among what I would call the literati of US journalism."
(11) Despite the irony of being an arch-scandaliser who found himself out-scandalised, Brenton doesn't bear a grudge.
(12) But infiltrators are not the only, or indeed the main problem; around three-quarters of the killings are prompted by personal grudges, the Nato-led mission to Afghanistan estimates.
(13) The other 200 or so Tory MPs who supported the prime minister did so grudgingly, Downing Street has been told.
(14) Female Tory MPs, struggling to be heard by sections of their party, speak with grudging admiration of Cooper's skill in sounding like someone who earns a relatively low wage and uses the night bus rather than a highly educated career politician.
(15) She is very bad in the afternoons, she says and tasks that bore her, like letter-writing and paperwork, are only grudgingly and belatedly attended to.
(16) While Mancunian hostilities resume at Old Trafford, and Roy Keane leads United against City, Haaland will be at home in his west Yorkshire village nursing a bad knee and an even worse grudge.
(17) There is no common thread, little evidence of infiltration and the majority of such attacks are the result of personal grudges.
(18) However gravely his voice, he is also thin-skinned and notorious for holding grudges , and I suspect that even his glad-handing of the Tea Party is merely in service of a larger goal: getting Liz elected.
(19) As a result, both governments could propose short-term reductions in pensions, unemployment benefit, wider welfare benefits and public sector wages as part of the package and get grudging acceptance.
(20) This condition had been grudgingly accepted by Yemen's official opposition parties, though the protesters on the streets, together with international human rights organisations, found it abhorrent.
Malice
Definition:
(n.) Enmity of heart; malevolence; ill will; a spirit delighting in harm or misfortune to another; a disposition to injure another; a malignant design of evil.
(n.) Any wicked or mischievous intention of the mind; a depraved inclination to mischief; an intention to vex, annoy, or injure another person, or to do a wrongful act without just cause or cause or excuse; a wanton disregard of the rights or safety of others; willfulness.
(v. t.) To regard with extreme ill will.
Example Sentences:
(1) After addition of triiodothyronine, malic enzyme mRNA accumulated with sigmoidal kinetics, approaching a new steady state at 36-48 h after adding hormone.
(2) In addition to detecting three major antigenic variants of malic enzyme within this group, both antisera readily reacted with Streptococcus faecalis malic enzyme.
(3) The oxidative enzymes of the pentose phosphate pathway, ATP-citrate lyase, 'malic' enzyme and fatty acid synthetase also decrease markedly.
(4) Hormone therapy also caused an increase in the rate of incorporation of [3H]leucine into soluble proteins and in malic enzyme activity.
(5) Moreover, the transcriptional rate, mRNA concentration and induction of malic enzyme were increased by triiodothyronine treatment at a similar rate in both the young and old rats, but the absolute increments were lower in the old animals.
(6) The TRH treatment suppressed mitochondrial cytochrome c reductase and glucose-6-phosphatase activities, whereas cyclo(His-Pro) reduced cytochrome c reductase and malic enzyme activities.
(7) Activities of glucose-6-phosphate dehydrogenase and malic dehydrogenase of the mycelial form were higher than those of the yeast form.
(8) These observations suggest that in the rat neostriatum there are some neurons especially able to catabolize pyruvate via cytosolic malic isoenzyme.
(9) Thus a long-lived event in thyroid hormone stimulation of malic enzyme synthesis occurred prior to transcription of a specific messenger RNA (mRNA), presumably malic enzyme mRNA.
(10) In the Ob 17 preadipocyte cell line, during adipose differentiation, T3 amplified the progressive expression of two enzymes of the lipogenic pathway, ATP-citrate lyase (ATP-CL) and malic enzyme (ME) as previously described for fatty acid synthase (FAS) and fatty acid synthesis, and in the same time-period of development.
(11) The nucleotide sequence of the mRNA for malic enzyme ((S)-malate NADP+ oxidoreductase (oxaloacetate-decarboxylating, EC 1.1.1.40) from rat liver was determined from three overlapping cDNA clones.
(12) The specific nuclear binding of triiodothyronine (T3) (NBT3) and the activity of malic enzyme (ME), glucose-6-phosphate-dehydrogenase (G6PD), and 6-phosphogluconate-dehydrogenase (6PGD) were studied in the human fibroblast cell (MRC-5).
(13) 2-Hydroxyisobutyric acid, ethyl-2-hydroxybutyrate, malic acid, 1-butanol, benzyl alcohol and L-leucine did not act as substrates for the enzymes.
(14) Malic enzyme and glucose-6-phosphate dehydrogenase were highly active in the adipose tissue of mammals but were inactive in the adipose tissue of birds.
(15) Distribution of kinase activity in centrifugal fractions of both liver and heart mitochondrial sonicates was parallel to that of the two inner membrane marker enzymes succinic dehydrogenase and cytochrome oxidase and quite different from that of the matrix enzyme malic dehydrogenase.
(16) Glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and malic enzyme are enzymes involved in NADPH synthesis.
(17) The antigenic enzymes, the precipitates of which are only stained by specific staining, are: aldolase, malic enzyme, acid phosphatase, peroxydase and cholinesterase.
(18) The coupling enzymes, fumarase (fumarate to L-malate) and malic enzyme (L-malate to pyruvate and NADPH), are adsorbed to nitrocellulose prior to blotting.
(19) The latter region apparently includes the malic dehydrogenase-1 gene.
(20) Some reactions, such as malic enzyme and glutamate dehydrogenase, may be inhibited or deleted with little or no adverse effect on the calculated cell growth rate.