(v. t.) To make hard or harder; to make firm or compact; to indurate; as, to harden clay or iron.
(v. t.) To accustom by labor or suffering to endure with constancy; to strengthen; to stiffen; to inure; also, to confirm in wickedness or shame; to make unimpressionable.
(v. i.) To become hard or harder; to acquire solidity, or more compactness; as, mortar hardens by drying.
(v. i.) To become confirmed or strengthened, in either a good or a bad sense.
Example Sentences:
(1) Osmotically treated red cells, red cells partially hardened with increasing glutaraldehyde concentrations, and mixtures of normal and hardened red cells were used to test the method.
(2) "But if public opposition to further austerity measures hardens, the Greek government could find it even tougher to put the public finances back on a sustainable footing."
(3) It's not as if they were once tolerant and have hardened their hearts as they've grown older.
(4) Insertion of an adequate approximate amalgam filling and its finish after hardening is one of the basic preventive measures in marginal periodontopathies.
(5) Hardened skin was markedly altered physiologically.
(6) A comparison was made of the kinetics of the carboxylation reaction of bicarbonate-magnesium-activated ribulose biphosphate carboxylase-oxygenase purified from cold-hardened and unhardened winter rye (Secale cereale L. cv.
(7) Rarely has there been a potential presidential candidate so battle-hardened and ready for combat.
(8) With its huge corps of jihadists hardened by years of fighting in Kashmir, it is arguably too big to confront at a time when Pakistan is battling the TTP.
(9) However, several systematic errors of the method have to be considered, such as the influence of fat present in the spongiosa in varying concentrations as well as beam hardening effects and different calibration methods.
(10) It is the sort of malevolent onslaught that has caused many hardened media pundits to quake.
(11) Values of elongation were more than 10% even after hardening heat treatment.
(12) It’s not an entirely controversy-free choice, considering that Harden hasn’t been a starter for more than two seasons, doesn’t have the best track record as far as being a team player goes and at times has been bad enough on defense that you could make an entire YouTube playlist devoted entirely to clips of him failing to make any defensive effort whatsoever.
(13) Compared to conventional CT, the new system should significantly improve contrast resolution of the image and provide better image quantification because of its lack of beam-hardening effects and its efficient implementation of energy-selective imaging methods such as dual-photon absorptiometry and K-edge subtraction with high-atomic-number (high-Z) contrast-enhancement elements.
(14) An earlier debt sustainability analysis was leaked in the days leading up to the Greek referendum and helped harden opposition to the (less draconian) terms then on offer.
(15) He also signalled a change in policy on welfare, hardening Labour’s opposition to the government’s welfare reforms, by pledging to oppose the cap on the total amount of benefits that a person can receive.
(16) The effects of DMSO and cooling on fertilization are likely to be due to zona hardening by cortical granule release and to disorganization of the egg cytoskeleton and plasma membrane.
(17) When present during the egg activation process monodansylcadaverine (MDC-a fluorescent lysine analog) inhibits eggshell hardening and at the same time becomes covalently incorporated into the eggshell.
(18) In rigor control, crossbridges were most regular in muscles that were stabilized before freezing by prefixation in glutaraldehyde followed by 'hardening' with neutralized tannic acid, so all nucleotide treatments were terminated by such fixation.
(19) It main advantage lies in the screening of arterial diseases (very reproductable and sensitive), monitoring of the treatment (unrelated to the operator), study of hardened arteries (diabetes).
(20) Evidence from several sources indicate that the catalytic action of the peroxidase is responsible for hardening the FE through the phenolic coupling of tyrosyl residues of the FE proteins.
Horny
Definition:
(superl.) Having horns or hornlike projections.
(superl.) Composed or made of horn, or of a substance resembling horn; of the nature of horn.
(superl.) Hard; callous.
Example Sentences:
(1) Digestion of cytoplasmic components of horny cells was observed by electron microscopy, but both cell membranes and desmosomes remained intact.
(2) Strains of C. albicans differing in their abilities to secrete proteinase in vitro and to produce germ tube were inoculated onto the skin surface of newborn mice, and the invasion of the yeast cells into the horny layer was examined by histological techniques.
(3) Morphologic features of Malassezia(M.) furfur in the horny layer from clinical lesions of tinea versicolor were examined by scanning electron microscopy and compared with the appearance of fungus in the horny layer from normal skin and in culture.
(4) The absolute concentrations of 8-Methoxypsoralen were estimated in the horny layer, epidermis and dermis.
(5) In the next stage, the roof consisting of the malpighian layers is disrupted, and the vesicular fluid comes into contact with the horny layer.
(6) The systematic evaluation of the original curves takes into consideration amplitude, angle of climb and medium route and results in a horny layer sample-obtained successively from one and the same horny layer strip-series test area-impressioned by individual and regional horny layer conditions.
(7) The nature of the horny layer which, as the uppermost barrier takes over the main part of the protective function of the skin against all locally applied substances, is shortly outlined.
(8) Removal of the horny layer decreased epidermal IL 1-like activity.
(9) The superficial dermis contained horny cysts, similar to those present on the cheeks.
(10) Munro's microabscess under the horny layer also included IFN-gamma producing cells.
(11) The fluid was obtained from the skin surface of female mongrel dogs by transcutaneous suction after removal of the horny substance.
(12) The mockery continued when he noted semi-automatics had only two purposes: to kill people, and to let their owners go to a shooting range, "yell yeehaw, and get all horny at the rapid fire and the burning vapor spurting from the end of the barrel".
(13) In both sites the plasma membranes of the horny cells were thickened and there was a cytoplasmic meshwork of microfibrils in the cells.
(14) Epithelial cells changing from the granular stage of differentiation to the horny stage are more numerous, and reveal sequential events of transformation in finer detail in the rumen epithelium than in other keratinizing epithelia thus far studied in the electron microscope.
(15) Yet there is Samantha, bawdy as the Wife of Bath, always cheerfully horny and materialistic, utterly without Calvinic redeeming qualities, living at last with her devoted younger boy toy in LA in the Sex and the City movie – finally leaving him because she is just not cut out to mix her driving, unmediated sexual energy with commitment.
(16) "Before you hit puberty, you have this growing, really urgent sense of horniness."
(17) This reflected enhanced permeability resulting from reduction of the horny layer to less than one-half its normal thickness.
(18) Remaining reactivity with antibodies, but not lectins, was almost completely abolished immediately before the final disintegration of the desmosome structure in the lower horny layer.
(19) The calcified concretions are also seen in the lymphatic capillaries, the intraepidermal sweat ducts and horny layer; at a site they perforate the epidermis and penetrate in a sweat pore.
(20) Elastic fibres were prominent in the upper dermis, the lower levels of the epidermis and in the hyperkeratotic horny layer.