(v. t.) To make hard or harder; to make firm or compact; to indurate; as, to harden clay or iron.
(v. t.) To accustom by labor or suffering to endure with constancy; to strengthen; to stiffen; to inure; also, to confirm in wickedness or shame; to make unimpressionable.
(v. i.) To become hard or harder; to acquire solidity, or more compactness; as, mortar hardens by drying.
(v. i.) To become confirmed or strengthened, in either a good or a bad sense.
Example Sentences:
(1) Osmotically treated red cells, red cells partially hardened with increasing glutaraldehyde concentrations, and mixtures of normal and hardened red cells were used to test the method.
(2) "But if public opposition to further austerity measures hardens, the Greek government could find it even tougher to put the public finances back on a sustainable footing."
(3) It's not as if they were once tolerant and have hardened their hearts as they've grown older.
(4) Insertion of an adequate approximate amalgam filling and its finish after hardening is one of the basic preventive measures in marginal periodontopathies.
(5) Hardened skin was markedly altered physiologically.
(6) A comparison was made of the kinetics of the carboxylation reaction of bicarbonate-magnesium-activated ribulose biphosphate carboxylase-oxygenase purified from cold-hardened and unhardened winter rye (Secale cereale L. cv.
(7) Rarely has there been a potential presidential candidate so battle-hardened and ready for combat.
(8) With its huge corps of jihadists hardened by years of fighting in Kashmir, it is arguably too big to confront at a time when Pakistan is battling the TTP.
(9) However, several systematic errors of the method have to be considered, such as the influence of fat present in the spongiosa in varying concentrations as well as beam hardening effects and different calibration methods.
(10) It is the sort of malevolent onslaught that has caused many hardened media pundits to quake.
(11) Values of elongation were more than 10% even after hardening heat treatment.
(12) It’s not an entirely controversy-free choice, considering that Harden hasn’t been a starter for more than two seasons, doesn’t have the best track record as far as being a team player goes and at times has been bad enough on defense that you could make an entire YouTube playlist devoted entirely to clips of him failing to make any defensive effort whatsoever.
(13) Compared to conventional CT, the new system should significantly improve contrast resolution of the image and provide better image quantification because of its lack of beam-hardening effects and its efficient implementation of energy-selective imaging methods such as dual-photon absorptiometry and K-edge subtraction with high-atomic-number (high-Z) contrast-enhancement elements.
(14) An earlier debt sustainability analysis was leaked in the days leading up to the Greek referendum and helped harden opposition to the (less draconian) terms then on offer.
(15) He also signalled a change in policy on welfare, hardening Labour’s opposition to the government’s welfare reforms, by pledging to oppose the cap on the total amount of benefits that a person can receive.
(16) The effects of DMSO and cooling on fertilization are likely to be due to zona hardening by cortical granule release and to disorganization of the egg cytoskeleton and plasma membrane.
(17) When present during the egg activation process monodansylcadaverine (MDC-a fluorescent lysine analog) inhibits eggshell hardening and at the same time becomes covalently incorporated into the eggshell.
(18) In rigor control, crossbridges were most regular in muscles that were stabilized before freezing by prefixation in glutaraldehyde followed by 'hardening' with neutralized tannic acid, so all nucleotide treatments were terminated by such fixation.
(19) It main advantage lies in the screening of arterial diseases (very reproductable and sensitive), monitoring of the treatment (unrelated to the operator), study of hardened arteries (diabetes).
(20) Evidence from several sources indicate that the catalytic action of the peroxidase is responsible for hardening the FE through the phenolic coupling of tyrosyl residues of the FE proteins.
Indurate
Definition:
(a.) Hardened; not soft; indurated.
(a.) Without sensibility; unfeeling; obdurate.
(v. t.) To make hard; as, extreme heat indurates clay; some fossils are indurated by exposure to the air.
(v. t.) To make unfeeling; to deprive of sensibility; to render obdurate.
(v. i.) To grow hard; to harden, or become hard; as, clay indurates by drying, and by heat.
Example Sentences:
(1) Phaso-contrast and interference microscopy investigations revealed in the damaged cells an induration of the sarcoplasmic matrix due to an increase in the dry matter concentration.
(2) The indurations from immediate and delayed hypersensitivity reactions were readily distinguishable, but the hyperthermic responses appeared to contain elements of both immediate and delayed hypersensitivity.
(3) This feature of ILC may also help explain why tumors may be palpable as areas of vague induration or thickening rather than as discrete masses.
(4) Since therapy performed by means of the moving head technique had beneficial effect on chronic prostatitis, plastic induration of the penis and the accompanying sexual potency disturbance, the method is recommended for use.
(5) Such a treatment augmented erythematous delayed reactions in animals immunized with BGG in CFA, but abolished induration at the reaction sites.
(6) While most of the clinical features--including diffuse mucosal inflammation, indurative edema, rash, and lymphadenopathy--are self-limiting, coronary artery aneurysms and the possibility of thrombotic occlusion occurs in up to 20% of children.
(7) We describe 2 patients who presented with chronic painful indurated swelling of one lower limb, thought at the time of referral to be due to chronic venous insufficiency.
(8) In the early postoperative period within an observation period from 3 to 19 months the characteristic and rather common complications in patients operated for hydrocele did not occur (hematocele, chylomas, which are mostly of ex vacuo type because of impaired blood supply and lymph system of the scrotum, abscesses, indurations of the scrotal and testicular tissues, relapses of the hydrocele, etc).
(9) Distal areas in systemic sclerosis (scleroderma), such as the dorsal skin of the hand are more frequently involved and more indurated than proximal areas.
(10) Clinical signs included lesions, indurations, and enlargement of lymph nodes.
(11) The precise basis of induration has not been established, although activation of the clotting system with consequent fibrin deposition has been clearly implicated.
(12) When IL-1 was injected intradermally into the backs of rabbits, the injection sites became indurated, erythematous, and warm to the touch after 4 hrs and annular lesions much like those of erythema chronicum migrans were seen in some animals after 24 hrs.
(13) In contrast to epicutaneous spongiotic contact dermatitis, HLA-DR was only seen on skin appendages and nearby basal keratinocytes in indurated tissue reactions with the exception of the reactions with focal basal cell layer disruption and an indurated patch test performed one week post angry back syndrome.
(14) A 52-year-old woman who had undergone an intrapleural sponge plombage operation because of tuberculosis, and had since shown an uneventful medical history for 35 years, was referred with a complaint of back skin induration over the previous surgical scar.
(15) The prevalence of tuberculous infection in a population is generally estimated from calculating the proportion of tested individuals who react with at least 10 mm of induration to 5 TU of PPD-S tuberculin.
(16) After 16 months, one of the two infected ewes suffered from indurative lymphocytic mastitis.
(17) In the guinea pigs an intradermal dose of PHA-P produced erythema and induration with a maximal response at 24 hours after the injection.
(18) Anergy, defined as no induration to any of four intradermal antigens, was present in 12%.
(19) Either the palpation method or the ball-point pen technique may be used to measure induration that results from TB skin testing.
(20) Similar, but less severe changes were seen at the site of skin tests on BCG-vaccinated subjects who were 'negative' by conventional criteria of measurement of dermal induration and they became greatly exaggerated after successful re-vaccination.