(v. t.) To make hard or harder; to make firm or compact; to indurate; as, to harden clay or iron.
(v. t.) To accustom by labor or suffering to endure with constancy; to strengthen; to stiffen; to inure; also, to confirm in wickedness or shame; to make unimpressionable.
(v. i.) To become hard or harder; to acquire solidity, or more compactness; as, mortar hardens by drying.
(v. i.) To become confirmed or strengthened, in either a good or a bad sense.
Example Sentences:
(1) Osmotically treated red cells, red cells partially hardened with increasing glutaraldehyde concentrations, and mixtures of normal and hardened red cells were used to test the method.
(2) "But if public opposition to further austerity measures hardens, the Greek government could find it even tougher to put the public finances back on a sustainable footing."
(3) It's not as if they were once tolerant and have hardened their hearts as they've grown older.
(4) Insertion of an adequate approximate amalgam filling and its finish after hardening is one of the basic preventive measures in marginal periodontopathies.
(5) Hardened skin was markedly altered physiologically.
(6) A comparison was made of the kinetics of the carboxylation reaction of bicarbonate-magnesium-activated ribulose biphosphate carboxylase-oxygenase purified from cold-hardened and unhardened winter rye (Secale cereale L. cv.
(7) Rarely has there been a potential presidential candidate so battle-hardened and ready for combat.
(8) With its huge corps of jihadists hardened by years of fighting in Kashmir, it is arguably too big to confront at a time when Pakistan is battling the TTP.
(9) However, several systematic errors of the method have to be considered, such as the influence of fat present in the spongiosa in varying concentrations as well as beam hardening effects and different calibration methods.
(10) It is the sort of malevolent onslaught that has caused many hardened media pundits to quake.
(11) Values of elongation were more than 10% even after hardening heat treatment.
(12) It’s not an entirely controversy-free choice, considering that Harden hasn’t been a starter for more than two seasons, doesn’t have the best track record as far as being a team player goes and at times has been bad enough on defense that you could make an entire YouTube playlist devoted entirely to clips of him failing to make any defensive effort whatsoever.
(13) Compared to conventional CT, the new system should significantly improve contrast resolution of the image and provide better image quantification because of its lack of beam-hardening effects and its efficient implementation of energy-selective imaging methods such as dual-photon absorptiometry and K-edge subtraction with high-atomic-number (high-Z) contrast-enhancement elements.
(14) An earlier debt sustainability analysis was leaked in the days leading up to the Greek referendum and helped harden opposition to the (less draconian) terms then on offer.
(15) He also signalled a change in policy on welfare, hardening Labour’s opposition to the government’s welfare reforms, by pledging to oppose the cap on the total amount of benefits that a person can receive.
(16) The effects of DMSO and cooling on fertilization are likely to be due to zona hardening by cortical granule release and to disorganization of the egg cytoskeleton and plasma membrane.
(17) When present during the egg activation process monodansylcadaverine (MDC-a fluorescent lysine analog) inhibits eggshell hardening and at the same time becomes covalently incorporated into the eggshell.
(18) In rigor control, crossbridges were most regular in muscles that were stabilized before freezing by prefixation in glutaraldehyde followed by 'hardening' with neutralized tannic acid, so all nucleotide treatments were terminated by such fixation.
(19) It main advantage lies in the screening of arterial diseases (very reproductable and sensitive), monitoring of the treatment (unrelated to the operator), study of hardened arteries (diabetes).
(20) Evidence from several sources indicate that the catalytic action of the peroxidase is responsible for hardening the FE through the phenolic coupling of tyrosyl residues of the FE proteins.
Quenching
Definition:
(p. pr. & vb. n.) of Quench
Example Sentences:
(1) The extreme quenching of the dioxetane chemiluminescence by both microsomes and phosphatidylcholine, as a model phospholipid, implies that despite the low quantum yield (approx.
(2) The drug is extracted from serum or urine with ethyl acetate, separated by TLC, and determined by fluorescence quenching densitometry.
(3) Formation of a complex between alpha-tocopherol or its analogues in the excited state and fatty acids or their hydroperoxides has been suggested basing on the fluorescence quenching experimental data.
(4) Quenching of intrinsic fluorescence of (Ca2+-Mg2+)-ATPase by acrylamide, performed in the presence of Ca2+, gave evidence for a single class of tryptophan residues with Stern-Volmer constant (KSV) of 10 M-1.
(5) The 23Na double-quantum signal was quenched in both the extracellular and the intracellular compartments with increasing concentration of Li in each compartment, along with an increase in the 23Na T1 both intra- and extracellularly.
(6) Binding increases the fluorescence intensity of Tyr-49 by 130% while the fluorescence of the hormone tyrosine is almost completely quenched.
(7) Addition of 2,6-dimethylbenzoquinone caused quenching of these absorbance changes.
(8) These observations lead to the hypothesis that acidosis quenches fluorescence in distal skin flaps.
(9) The degree of quenching was accurately predicted by a simple relation derived in this paper, as well as a more complex equation previously developed by Tweet, et al.
(10) Subtilin may slightly enter the hydrophobic core as suggested by tryptophan fluorescence quenching and liposome fusion experiments.
(11) Greater than 99% of the polymerization reaction products were quenched by the addition of 2.0 mM ascorbate.
(12) Acoustic probe-based assays can enhance assay and laboratory efficiency through testing for multiple analytes in a single sample or increasing available binding surface area (by using probe and well surfaces simultaneously), and by eliminating quenching.
(13) The second-order rate constants appear to be at least 3 orders of magnitude lower than the second-order constants for quenching of the fluorescent probes; this is taken as a clear indication that ubiquinone diffusion is not the rate-determining step in the quinone-enzyme interaction.
(14) Accessibility to iodide was much lower, as was the rate of quenching by iodide, adding support to the conclusions from acrylamide quenching.
(15) An ATP-dependent, N-ethylmaleimide-inhibitable, 3,3',4',5-tetrachlorosalicylanilide-reversible, and chloride-attenuated quench of bis(1,3-dibutylbarbituric acid-(5] pentamethinoxonol fluorescence was seen, consistent with net transfer of positive charge into the vesicles.
(16) Quenching data indicated that five out of 22 tryptophans in CBH are surface-localized and are available for quenching with both KI and acrylamide, and three other tryptophans are buried and are available only to acrylamide.
(17) Acid quenching of a stiochiometric reaction between Ac(= S)CoA and citrate synthase following the transient quantitatively regenerates Ac(= S)CoA, indicating carbon-carbon bond formation had not yet occurred.
(18) The pulsed laser photolysis products of the charge-transfer quenching reaction were examined.
(19) The highest yield of amino acids with the quench reaction was 9 x 10-7 molecules per erg of input energy.
(20) Tris-washed chloroplast enriched in the photosystem II reaction center species Z+Q- and ZQ- are nearly four times more sensitive to nitrobenzene quenching than those enriched in Z+Q.