(n.) To have a great aversion to, with a strong desire that evil should befall the person toward whom the feeling is directed; to dislike intensely; to detest; as, to hate one's enemies; to hate hypocrisy.
(n.) To be very unwilling; followed by an infinitive, or a substantive clause with that; as, to hate to get into debt; to hate that anything should be wasted.
(n.) To love less, relatively.
(v.) Strong aversion coupled with desire that evil should befall the person toward whom the feeling is directed; as exercised toward things, intense dislike; hatred; detestation; -- opposed to love.
Example Sentences:
(1) She read geography at Oxford, where Benazir Bhutto (a future prime minister of Pakistan, assassinated in 2007) introduced May to her future husband, Philip May: "I hate to say this, but it was at an Oxford University Conservative Association disco… this is wild stuff.
(2) He had links to networks including the Hammerskin Nation and was involved in an underground music scene often referred to as "white power music" or "hate rock".
(3) The education secretary's wife, Sarah Vine, a columnist, said her son William, nine, and daughter Beatrice, 11, now realise how much their father is hated for his position in government because other children tell them in the playground.
(4) I went to a reasonably good school, though I think I hated the headmaster just as much as he hated me.
(5) Free speech has protected hate speech, and opponents of censorship have consistantly defended the rights of unscrupulous populists and incendiarists.
(6) And of course, as the articles are shared far and wide across the apparently much-hated web, they become gospel to those who read them and unfortunately become quasi-religious texts to musicians of all stripes who blame the internet for everything that is wrong with their careers.
(7) The US started down this course during the Sony hack last year, and in this case, transparency might be the best deterrent in the future – which, by the way, is something both Snowden and the Snowden-hating national security blog Lawfare argued on Monday.
(8) One tip was that he should not mention he was flying to Germany as "obviously" the environmentalists "hate short-haul flights".
(9) We hate the police, hate the government, got no opportunities ... Manchester was like a bloodbath.
(10) I think that those who go there, to Isis, they hate Russia for the conditions they have to endure to live,” Nazarov’s brother says.
(11) "And of course it's the kind of thing that leftwing pressure groups hate.
(12) The genius of a democracy governed by the rule of law, our democracy, is that it both empowers the majority through the ballot box, and constrains the majority, its government, so that it is bound by law.” Turnbull added: “Why does Daesh [another term for Islamic State] hate us?
(13) The worst purveyors of hate, they’re emboldened by this election and they’re out in force.
(14) All of which would be perfectly normal (after all, if there's anything valencianos love more than blowing off their fingers, it's complaining about their team) but for one thing: it was only just after half past nine and there was still an hour to go against hated rivals Real Madrid.
(15) Corbyn’s ‘new politics’ is neither hateful nor pure: it’s complicated | John Harris Read more Their dilemma is plain: if they make a stand against what is happening, they stand accused of disloyalty by Corbyn’s supporters; but if they go along with it, they are complicit in Labour’s probable disintegration when voters realise the party has been taken over by people they can never vote for.
(16) Of course they have… so they must be doing it because they hate you!
(17) Through small and large acts of deprivation and destruction we follow the process: the removal of hope, of dignity, of luxury, of necessity, of self; the reduction of a man to a hoarder of grey slabs of bread and the scrapings of a soup bowl (wonderfully told all this, with a novelist's gift for detail and sometimes very nearly comic surprise), to the confinement of a narrow bed – in which there is "not even any room to be afraid" – with a stranger who doesn't speak your language, to the cruel illogicality of hating a fellow victim of oppression more than you hate the oppressor himself – one torment following another, and even the bleak comfort of thinking you might have touched rock bottom denied you as, when the most immediate cause of a particular stress comes to an end, "you are grievously amazed to see that another one lies behind; and in reality a whole series of others".
(18) Listen to Stoopid Symbol Of Woman Hate or Can't Stand Up For 40-Inch Busts (both songs were inspired by a hatred of sexist advertising) and you can hear Amon Duul and Hawkwind scaring the living shit out of Devo and Clock DVA.
(19) At first Shevchenko hated the idea of protesting topless.
(20) It was his story, and lately I have come to hate stories.
Malice
Definition:
(n.) Enmity of heart; malevolence; ill will; a spirit delighting in harm or misfortune to another; a disposition to injure another; a malignant design of evil.
(n.) Any wicked or mischievous intention of the mind; a depraved inclination to mischief; an intention to vex, annoy, or injure another person, or to do a wrongful act without just cause or cause or excuse; a wanton disregard of the rights or safety of others; willfulness.
(v. t.) To regard with extreme ill will.
Example Sentences:
(1) After addition of triiodothyronine, malic enzyme mRNA accumulated with sigmoidal kinetics, approaching a new steady state at 36-48 h after adding hormone.
(2) In addition to detecting three major antigenic variants of malic enzyme within this group, both antisera readily reacted with Streptococcus faecalis malic enzyme.
(3) The oxidative enzymes of the pentose phosphate pathway, ATP-citrate lyase, 'malic' enzyme and fatty acid synthetase also decrease markedly.
(4) Hormone therapy also caused an increase in the rate of incorporation of [3H]leucine into soluble proteins and in malic enzyme activity.
(5) Moreover, the transcriptional rate, mRNA concentration and induction of malic enzyme were increased by triiodothyronine treatment at a similar rate in both the young and old rats, but the absolute increments were lower in the old animals.
(6) The TRH treatment suppressed mitochondrial cytochrome c reductase and glucose-6-phosphatase activities, whereas cyclo(His-Pro) reduced cytochrome c reductase and malic enzyme activities.
(7) Activities of glucose-6-phosphate dehydrogenase and malic dehydrogenase of the mycelial form were higher than those of the yeast form.
(8) These observations suggest that in the rat neostriatum there are some neurons especially able to catabolize pyruvate via cytosolic malic isoenzyme.
(9) Thus a long-lived event in thyroid hormone stimulation of malic enzyme synthesis occurred prior to transcription of a specific messenger RNA (mRNA), presumably malic enzyme mRNA.
(10) In the Ob 17 preadipocyte cell line, during adipose differentiation, T3 amplified the progressive expression of two enzymes of the lipogenic pathway, ATP-citrate lyase (ATP-CL) and malic enzyme (ME) as previously described for fatty acid synthase (FAS) and fatty acid synthesis, and in the same time-period of development.
(11) The nucleotide sequence of the mRNA for malic enzyme ((S)-malate NADP+ oxidoreductase (oxaloacetate-decarboxylating, EC 1.1.1.40) from rat liver was determined from three overlapping cDNA clones.
(12) The specific nuclear binding of triiodothyronine (T3) (NBT3) and the activity of malic enzyme (ME), glucose-6-phosphate-dehydrogenase (G6PD), and 6-phosphogluconate-dehydrogenase (6PGD) were studied in the human fibroblast cell (MRC-5).
(13) 2-Hydroxyisobutyric acid, ethyl-2-hydroxybutyrate, malic acid, 1-butanol, benzyl alcohol and L-leucine did not act as substrates for the enzymes.
(14) Malic enzyme and glucose-6-phosphate dehydrogenase were highly active in the adipose tissue of mammals but were inactive in the adipose tissue of birds.
(15) Distribution of kinase activity in centrifugal fractions of both liver and heart mitochondrial sonicates was parallel to that of the two inner membrane marker enzymes succinic dehydrogenase and cytochrome oxidase and quite different from that of the matrix enzyme malic dehydrogenase.
(16) Glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and malic enzyme are enzymes involved in NADPH synthesis.
(17) The antigenic enzymes, the precipitates of which are only stained by specific staining, are: aldolase, malic enzyme, acid phosphatase, peroxydase and cholinesterase.
(18) The coupling enzymes, fumarase (fumarate to L-malate) and malic enzyme (L-malate to pyruvate and NADPH), are adsorbed to nitrocellulose prior to blotting.
(19) The latter region apparently includes the malic dehydrogenase-1 gene.
(20) Some reactions, such as malic enzyme and glutamate dehydrogenase, may be inhibited or deleted with little or no adverse effect on the calculated cell growth rate.