(superl.) Heaved or lifted with labor; not light; weighty; ponderous; as, a heavy stone; hence, sometimes, large in extent, quantity, or effects; as, a heavy fall of rain or snow; a heavy failure; heavy business transactions, etc.; often implying strength; as, a heavy barrier; also, difficult to move; as, a heavy draught.
(superl.) Not easy to bear; burdensome; oppressive; hard to endure or accomplish; hence, grievous, afflictive; as, heavy yokes, expenses, undertakings, trials, news, etc.
(superl.) Laden with that which is weighty; encumbered; burdened; bowed down, either with an actual burden, or with care, grief, pain, disappointment.
(superl.) Slow; sluggish; inactive; or lifeless, dull, inanimate, stupid; as, a heavy gait, looks, manners, style, and the like; a heavy writer or book.
(superl.) Strong; violent; forcible; as, a heavy sea, storm, cannonade, and the like.
(superl.) Loud; deep; -- said of sound; as, heavy thunder.
(superl.) Dark with clouds, or ready to rain; gloomy; -- said of the sky.
(superl.) Impeding motion; cloggy; clayey; -- said of earth; as, a heavy road, soil, and the like.
(superl.) Not raised or made light; as, heavy bread.
(superl.) Not agreeable to, or suitable for, the stomach; not easily digested; -- said of food.
(superl.) Having much body or strength; -- said of wines, or other liquors.
(superl.) With child; pregnant.
(adv.) Heavily; -- sometimes used in composition; as, heavy-laden.
(v. t.) To make heavy.
Example Sentences:
(1) We were instantly refused entrance by the heavies at the door.
(2) With the exception of PMMA and PTFE, all plastics leave a very heavy tar- and soot deposit after burning.
(3) One-nation prime ministers like Cameron found the libertarians useful for voting against taxation; inconvenient when they got too loud about heavy-handed government.
(4) The prevalence was also higher in medium and heavy smokers.
(5) These results indicate that the inhibition of CarAc by heavy metals occurs by binding of the sulfhydryl on the enzyme by the metals.
(6) The biggest single source of air pollution is coal-fired power stations and China, with its large population and heavy reliance on coal power, provides $2.3tn of the annual subsidies.
(7) The combined evidence from immunoglobulin light chain staining and the analysis of immunoglobulin heavy chain gene rearrangement indicated that the lesions in most patients represented polyclonal proliferations that gave rise to clonal subpopulations.
(8) Variations in light chain composition, particularly fast and slow myosin light chain 1, appeared to occur independently of the variations in heavy chain composition, suggesting that some myosin molecules consist of mixtures of slow- and fast-type subunits.
(9) In general, enzyme activity was strongly reduced by heavy metal inorganic cations; less strongly by organometallic cations, some anions, and certain pesticides; and weakly inhibited by light metal cations and organometallic and organic compounds.
(10) But the condition of edifices such as B30 and B38 - and all the other "legacy" structures built at Sellafield decades ago - suggest Britain might end up paying a heavy price for this new commitment to nuclear energy.
(11) By applying this method to rat cardiac whole muscle, high-molecular weight proteins, such as myosin heavy chains, are focused on the first-dimensional gels and, in addition, minor components are resolved on the second-dimensional gels, without loss during equilibration with detergent.
(12) To identify cells of different myogenic lineages, myotubes were analyzed for content of fast and slow classes of myosin heavy chain (MHC) isoforms by immunocytochemistry and immunoblotting using specific monoclonal antibodies.
(13) Horses in heavy training may require more energy than they can consume on a conventional diet.
(14) As yet the observations demonstrate that workers exposed in their occupation to heavy metals (cadmium, lead, metalic mercury) and organic solvents should be subjected to special control for detection of renal changes.
(15) Heavy death losses (59%) occurred in adult Mystromys 3--14 days after muscle biopsies were taken from their rear legs.
(16) A comparative analysis of the structure and reactivity of the recombinant monoclonal antibodies showed that the light and heavy Ig-specific chains could form the reactive antibodies when the chains were present in different paratopes of Ig molecules.
(17) Mononucleosomes obtained from labeled cells were fractionated by rate zonal sedimentation through a sucrose gradient in heavy water (Senshu et al.
(18) Previous epitope mapping studies of human factor VIII (FVIII) inhibitor antibodies with heavy chain specificity localized epitopes to the amino-terminal half of the FVIII A2 domain.
(19) The ABI figures revealed that the best annuity for someone who is a heavy smoker and has severely impaired health was at Prudential, which paid out 46% more than the worst, from Friends Life.
(20) The parasites were highly aggregated within the study community, with most people harbouring low burdens while a few individuals harboured very heavy burdens.
High
Definition:
(v. i.) To hie.
(superl.) Elevated above any starting point of measurement, as a line, or surface; having altitude; lifted up; raised or extended in the direction of the zenith; lofty; tall; as, a high mountain, tower, tree; the sun is high.
(superl.) Regarded as raised up or elevated; distinguished; remarkable; conspicuous; superior; -- used indefinitely or relatively, and often in figurative senses, which are understood from the connection
(superl.) Elevated in character or quality, whether moral or intellectual; preeminent; honorable; as, high aims, or motives.
(superl.) Exalted in social standing or general estimation, or in rank, reputation, office, and the like; dignified; as, she was welcomed in the highest circles.
(superl.) Of noble birth; illustrious; as, of high family.
(superl.) Of great strength, force, importance, and the like; strong; mighty; powerful; violent; sometimes, triumphant; victorious; majestic, etc.; as, a high wind; high passions.
(superl.) Very abstract; difficult to comprehend or surmount; grand; noble.
(superl.) Costly; dear in price; extravagant; as, to hold goods at a high price.
(superl.) Arrogant; lofty; boastful; proud; ostentatious; -- used in a bad sense.
(superl.) Possessing a characteristic quality in a supreme or superior degree; as, high (i. e., intense) heat; high (i. e., full or quite) noon; high (i. e., rich or spicy) seasoning; high (i. e., complete) pleasure; high (i. e., deep or vivid) color; high (i. e., extensive, thorough) scholarship, etc.
(superl.) Strong-scented; slightly tainted; as, epicures do not cook game before it is high.
(superl.) Acute or sharp; -- opposed to grave or low; as, a high note.
(superl.) Made with a high position of some part of the tongue in relation to the palate, as / (/ve), / (f/d). See Guide to Pronunciation, // 10, 11.
(adv.) In a high manner; in a high place; to a great altitude; to a great degree; largely; in a superior manner; eminently; powerfully.
(n.) An elevated place; a superior region; a height; the sky; heaven.
(n.) People of rank or high station; as, high and low.
(n.) The highest card dealt or drawn.
(v. i.) To rise; as, the sun higheth.
Example Sentences:
(1) Cancer patients showed abnormally high plasma free tryptophan levels.
(2) Results by these three assays were also highly reproducible.
(3) This trend appeared to reverse itself in the low dose animals after 3 hr, whereas in the high dose group, cardiac output continued to decline.
(4) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(5) The rash presented either as a pityriasis rosea-like picture which appeared about three to six months after the onset of treatment in patients taking low doses, or alternatively, as lichenoid plaques which appeared three to six months after commencement of medication in patients taking high doses.
(6) The angiographic appearances are highly characteristic and equal in value to a histological diagnosis.
(7) When micF was cloned into a high-copy-number plasmid it repressed ompF gene expression, whereas when cloned into a low-copy-number plasmid it did not.
(8) We also show that proliferation of primary amnion cells is not dependent on a high c-fos expression, suggesting that the function of c-fos is more likely to be associated with other cellular functions in the differentiated amnion cell.
(9) The high amino acid levels in the cells suggest that these cells act as inter-organ transporters and reservoirs of amino acids, they have a different role in their handling and metabolism from those of mammals.
(10) after operation for hip fracture, and merits assessment in other high-risk groups of patients.
(11) Villagers, including one man who has been left disabled and the relatives of six men who were killed, are suing ABG in the UK high court, represented by British law firm Leigh Day, alleging that Tanzanian police officers shot unarmed locals.
(12) PMS is more prevalent among women working outside the home, alcoholics, women of high parity, and women with toxemic tendency; it probably runs in families.
(13) Simplicity, high capacity, low cost and label stability, combined with relatively high clinical sensitivity make the method suitable for cost effective screening of large numbers of samples.
(14) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
(15) Five probes of high specificity to individual chromosomes (chromosomes 3, 11, 17, 18 and X) were hybridized in situ to metaphase chromosomes of different individuals.
(16) Morphological alterations in the lungs of pheasants after prolonged high-dosage administration of bleomycin sulfate were studied by light and electron microscopy.
(17) In vitro studies carried out in this Department confirmed the high activity of mecillinam against Salmonella spp.
(18) The high transition enthalpy for kerasin is ascribed to a lesser accommodation of gauche conformers in the hydrocarbon chains just below the transition temperature.
(19) beta-Endorphin blocked the development of fighting responses when a low footshock intensity was used, but facilitated it when a high shock intensity was delivered.
(20) Multiple overlapping thin 3D slab acquisition is presented as a magnitude contrast (time of flight) technique which combines advantages from multiple thin slice 2D and direct 3D volume acquisitions to obtain high-resolution cross-sectional images of vessel detail.