(n.) One who inherits, or is entitled to succeed to the possession of, any property after the death of its owner; one on whom the law bestows the title or property of another at the death of the latter.
(n.) One who receives any endowment from an ancestor or relation; as, the heir of one's reputation or virtues.
(v. t.) To inherit; to succeed to.
Example Sentences:
(1) Antoine Comte, a lawyer for the Schloss heirs, said all the family wanted was the return of the painting.
(2) Diana of the sapphire eyes was rated more perfect than Botticelli's Venus and attracted Bryan Guinness, heir to the brewing fortune, as soon as she was out in society.
(3) They are most commonly described as conduct disordered and hyperactive, appear heir to a variety of deficits in verbal and abstract cognition, and perform more poorly in the academic environment.
(4) Another example is the death in 1817 of Princess Charlotte, in childbirth, which led to the scramble of George III's aging sons to marry and beget an heir to the throne.
(5) Museveni, who has held power for nearly three decades, has never said he sees his son as his political heir.
(6) Throughout his career he has continued to champion Crane, seeing him as the direct heir to Walt Whitman – Whitman being "not just the most American of poets but American poetry proper, our apotropaic champion against European culture" – and slayer of neo-Christian adversaries such as "the clerical TS Eliot" and the old New Critics, who were and are anathema to Bloom, unresting defender of the Romantic tradition.
(7) Her parents, Apiruj and Wanthanee Suwadee, were found guilty of violating Article 112 of Thailand’s criminal code which says anyone who “defames, insults or threatens the king, the queen, the heir-apparent or the regent” will be punished with up to 15 years in prison.
(8) The anointed heir, Xi Jinping , commanded less attention than former general secretary Jiang Zemin, seated next to current leader Hu Jintao.
(9) The two reformists Mr Mousavi and Mehdi Karroubi have sought to portray themselves as the true heirs of the Islamic revolution's spiritual leader, the late Ayatollah Khomeini, but this tactic has since worn thin and Khomeini's successor Ayatollah Ali Khamenei has stepped up his drive to paint Mousavi and Karroubi as western-run heretics.
(10) Welsh, but London-based, Jones's real offence to leftwingers - heirs to Nye Bevan - was to be a Blairite, "parachuted" into Blaenau Gwent.
(11) Revelations about Charles' power of consent come amid continued concern that the heir to the throne may be overstepping his constitutional role by lobbying ministers directly and through his charities on pet concerns such as traditional architecture and the environment.
(12) In the past, they were mostly wealthy British citizens seeking to hold their money outside the UK to avoid income tax and capital gains tax on their earnings, and to pass their wealth to heirs without inheritance tax.
(13) The spectacular ascent that saw him grace the cover of Newsweek as Asian of the Year and become the heir apparent of then prime minister Mahathir Mohamad was met with an equally spectacular crash in 1998, when the two fell out and Anwar was imprisoned for six years on corruption and sodomy charges, claims he repeatedly dismissed as politically motivated.
(14) The American heirs of a German-Jewish family have launched an unprecedented partnership with German state institutions to try to recover a vast art collection stolen by the Nazis.
(15) For seven years, the government has been fighting to prevent the disclosure of the letters – dubbed "black spider memos" because of the heir's handwriting.
(16) Tim Loughton, a Sussex MP, said it would be a "nonsense" to stop the heir to the throne talking to ministers as he had always come across as "well briefed and knowledgeable" in their meetings.
(17) But both Kennedy and Marks are now dead and Mossa said they had been unable to establish an obvious heir.
(18) Carter and the former leaders of Finland, Norway and Ireland were hoping for talks with Kim Jong-il and his son and heir apparent, Kim Jong-un.
(19) The gene termed heir-1 was localized to the neuroblastoma consensus deletion at 1p36.2-p36.12.
(20) Since Evans’ original request to see Charles’s letters, the government tightened up the Freedom of Information Act to provide an “absolute exemption” on all requests relating to the Queen and the heir to the throne.
Hir
Definition:
(pron.) See Here, pron.
Example Sentences:
(1) Anti-synthetic HIRP(957-980) serum HIR-27 was proved to cross-react with HIRP-related proteins in solubilized human placental membranes.
(2) We have investigated insulin responsiveness in relation to insulin sensitivity during sequential hyperglycemic clamping in low insulin responders (LIR), high insulin responders (HIR) and in women with a history of gestational diabetes (GD).
(3) 80% of internalized receptors after 20 min), the internalization in HIR-B cells reaches a maximum (approx.
(4) Human insulin receptor substrate-1 (hIRS-1) cDNAs were cloned from a lambda GT11 expression library using a monoclonal antibody (MAb) produced against a human hepatocellular carcinoma (HCC) cell line (FOCUS).
(5) Within 3 h after exposure to 70 nM insulin, ODC enzyme activity increased approximately 50-fold and mRNA accumulation 3-fold in the HIR 3.5 cells but not in normal fibroblasts.
(6) To further explore the specificity of the IR tyrosine phosphokinase (TPK) domain in IR function, we have altered the human IR (hIR) cDNA to encode truncated insulin-independent TPKs, which are expressed in chinese hamster ovary (CHO) cells as either membrane-anchored or cytosolic proteins.
(7) Glucose disposal and whole body carbohydrate oxidation were markedly lower in NIR and HIR vs. NIS (P less than 0.001 for disposal and oxidation).
(8) Internalization, degradation, and insulin-induced down-regulation of insulin receptors were studied comparatively in transformed Chinese hamster ovary (CHO) cell lines, CHO.T and CHO.IR.ros, respectively expressing either the wild-type human insulin receptor (hIR) or a mutated hybrid receptor in which the transmembrane and cytoplasmic domains of hIR were replaced by corresponding domains of the transforming protein p68gag-ros (v-ros) of avian sarcoma virus UR2.
(9) In conclusion, the HIR delta CT receptor retains intact protein kinase activity in vitro.
(10) Cells expressing 6.4 X 10(3) and 1.25 X 10(6) normal receptors and 2.5 X 10(5) HIR delta CT receptors, as well as control Rat 1 fibroblasts were selected for further analysis.
(11) Highly intensive physical loading suppresses the development of DH and enhances the suppressive effect of staphylococci on SRBC-induced HIR.
(12) Our experiments with the hIR protein have been designed to address a very general question of transmembrane receptor structure and function: What are the roles and interactions of the various deduced structural domains of such molecules in the initiation of the response of cells to extracellular signals?
(13) Mono- and polyauxotrophic mutant of I, II and R-phases by hir, ilv, pro, and mtl markers were obtained by treatment of Sh.
(14) Physical loading of low intensity normalizes staphylococcus-suppressed HIR to SRBC, but produces no effect on staphylococcus-induced DH.
(15) Transfection of normal HIR cDNA produced normal insulin receptors on the plasma membranes in COS 7 cells.
(16) Incubation for 18 hrs with 1 microM insulin resulted in a similar decrease (to approximately 35% of control) of all the hIR mRNA species.
(17) Seven regions of the alpha subunit of human insulin receptor (HIR) were synthesized and examined for their ability to bind radioiodinated insulin.
(18) This cDNA (HIR delta CT), as well as cDNA encoding the complete receptor (HIRc) was transfected into Rat 1 fibroblasts.
(19) To this end the following receptor model system consisting of two receptors was co-expressed in NIH 3T3 cells: a kinase inactive human insulin receptor (HIR K1018A) and a chimeric (EIR) receptor corresponding to the extracellular and transmembrane domains of the human EGF receptor and the cytosolic domain of the human insulin receptor beta subunit.
(20) The resulting virus, named UIR, contains the hIR sequence fused to the 5' portion of the UR2 gag gene coding for p19.