(n.) A substance, in the form of reddish brown, microscopic, prismatic crystals, formed from dried blood by the action of strong acetic acid and common salt; -- called also Teichmann's crystals. Chemically, it is a hydrochloride of hematin.
Example Sentences:
(1) The appearance of an abundant class of polyribosomes was correlated with globin synthesis by demonstrating that a discrete class of polyribosomes arises in cells treated with the inducers hexamethylene bisacetamide and hemin.
(2) Finding (d) indicates that steps involved in the restorative effect of these compounds may not contribute to the stimulation of the globin synthesis in hemin-deficient lysates.
(3) The destabilization of the red cell membrane skeleton in the presence of crude iHCR is caused by release of hemin, which lowers the stability of membrane skeleton by weakening the spectrin-protein 4.1-actin interaction.
(4) Hemin failed to increase P450 levels previously depressed by TPA indicating that TPA acts by lowering apocytochrome levels.
(5) Prior exposure of the adherent cell layer to high concentrations of hemin (10 microM) was found to have a beneficial effect on the support of newly seeded cultures; however, the effect of lower hemin concentrations (0.1-1 microM) on stromal cell layer formation was not significant.
(6) Hemin increased satellite cell fusion by 27%, but decreased cell proliferative rate by 30%.
(7) Inhibition of hemin-mediated O2 activation by bovine superoxide dismutase and the copper tetrammine complex has been examined.
(8) Upon incubation of the HCI preparation with hemin (5-10 microM), the eIF-2 alpha kinase is converted into an inactive form and appears to become associated with related peptides forming high molecular weight complexes which can be reversibly activated by 2-mercaptoethanol.
(9) When the prorepressor is converted to the hemin-controlled translational repressor, either by prolonged warming in the absence of hemin or by incubation with N-ethylmaleimide for 5 min, and then incubated briefly with [gamma-32P]-ATP and Mg2+, a protein that migrates as a 100 000 molecular weight component on sodium dodecyl sulfate-polyacrylamide gels becomes phosphorylated.
(10) Its activity is independent of cyclic AMP as well as of the calcium-dependent regulator protein and is inhibited by hemin.
(11) The spin-labeled hemins were recombined with apoproteins of hemoglobin (Hb), myoglobin (Mb), cytochrome c peroxidase (EC 1.11.1.5) and horseradish peroxidase (EC 1.11.1.7).
(12) A model compound with similar optical properties to the CO-ligated protein can be prepared in dimethyl sulfoxide from hemin chloride, imidazole, and CO using chromous acetate as the heme reductant.
(13) Porphyromonas gingivalis is capable of in vitro growth when iron sources are either complexed to hemin or host iron transport proteins, or exist in an inorganic form.
(14) An assumption is advanced that the P. vitale catalase contains two hemin groups located in two protein subunits.
(15) The effect of hemin administration on the level of hepatic delta-amino-levulinate synthase mRNA was also examined.
(16) We were not able to detect any reaction between the radical (see article) and the hemin group (which would result in a complex such as heme O-2).
(17) The N-acetylimidazole-reacted apoprotein supplemented with hemin and reacted with hydroperoxides, neither showed electronic absorption spectra of higher oxidation states nor an EPR doublet signal due to a tyrosyl radical.
(18) With iron porphyrins (hemin, heme and their complexes) the charge of the iron and the nature of axial ligands determine the position and intensity of the O-bands in the MOR spectrum.
(19) Since S. typhimurium LT2 is not able to incorporate hemin, the identification of the mutants not stimulated by Delta-ALA was made on the basis of the simultaneous loss of catalase activity and cytochromes.
(20) Hemin, known to inactivate IRF in vivo, showed a similar, reversible effect in vitro, presumably by oxidizing IRF.
Test
Definition:
(n.) A cupel or cupelling hearth in which precious metals are melted for trial and refinement.
(n.) Examination or trial by the cupel; hence, any critical examination or decisive trial; as, to put a man's assertions to a test.
(n.) Means of trial; as, absence is a test of love.
(n.) That with which anything is compared for proof of its genuineness; a touchstone; a standard.
(n.) Discriminative characteristic; standard of judgment; ground of admission or exclusion.
(n.) Judgment; distinction; discrimination.
(n.) A reaction employed to recognize or distinguish any particular substance or constituent of a compound, as the production of some characteristic precipitate; also, the reagent employed to produce such reaction; thus, the ordinary test for sulphuric acid is the production of a white insoluble precipitate of barium sulphate by means of some soluble barium salt.
(v. t.) To refine, as gold or silver, in a test, or cupel; to subject to cupellation.
(v. t.) To put to the proof; to prove the truth, genuineness, or quality of by experiment, or by some principle or standard; to try; as, to test the soundness of a principle; to test the validity of an argument.
(v. t.) To examine or try, as by the use of some reagent; as, to test a solution by litmus paper.
(n.) A witness.
(v. i.) To make a testament, or will.
(n.) Alt. of Testa
Example Sentences:
(1) Multiple stored energy levels were randomly tested and the percent successful defibrillation was plotted against the stored energy, and the raw data were fit by logistic regression.
(2) In January 2011, the Nobel peace prize laureate was admitted to a Johannesburg hospital for what officials initially described as tests but what turned out to be an acute respiratory infection .
(3) It was tested for recovery and separation from other selenium moieties present in urine using both in vivo-labeled rat urine and human urine spiked with unlabeled TMSe.
(4) These results indicated that the PG determination was the most accurate predictor of fetal lung well-being prior to birth among the clinical tests so far reported.
(5) Clinical surveillance, repeated laboratory tests, conventional radiology, and especially ultrasonography and CT scan all contributed to the preoperative diagnosis.
(6) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(7) LHRH therapy leads to higher plasma LH levels and a lower FSH in response to an intravenous LHRH test.
(8) Of the patients 73% demonstrated clinically normal sensibility test results within 23 days after operation.
(9) Neuropsychological testing is a relatively new field in the area of clinical neuroscience.
(10) Thirteen patients with bipolar affective illness who had received lithium therapy for 1-5 years were tested retrospectively for evidence of cortical dysfunction.
(11) Our data suggest that a rational use of surveillance cultures and serological tests may aid in an earlier diagnosis of FI in BMT patients.
(12) The HBV infection was tested by the reversed passive hemagglutination method for the HBsAg and by the passive hemagglutination method for the anti-HBs at the time of recruitment in 1984.
(13) The testing of other models and their failure to describe the kinetic observations are discussed.
(14) It was shown in experiments on four dogs by the conditioned method that the period of recovery of conditioned activity after one hour ether anaesthesia tested 7 to 7.5 days.
(15) Recently, the validity of the American Thoracic Society (ATS) standards for selection of spirometric test results has been questioned based on the finding of inverse dependence of FEV1 on effort.
(16) The hemodynamic efficiency of the drive was tested in a number of in vivo experiments.
(17) Serum samples from 23 families, including a total of 48 affected children, were tested for a set of "classical markers."
(18) Tests showed the cells survive and function normally in animals and reverse movement problems caused by Parkinson's in monkeys.
(19) The promoters of the adenovirus 2 major late gene, the mouse beta-globin gene, the mouse immunoglobulin VH gene and the LTR of the human T-lymphotropic retrovirus type I were tested for their transcription activities in cell-free extracts of four cell lines; HeLa, CESS (Epstein-Barr virus-transformed human B cell line), MT-1 (HTLV-I-infected human T cell line without viral protein synthesis), and MT-2 (HTLV-I-infected human T cell line producing viral proteins).
(20) Immunocompetence was also evident when the cells from thymectomized donors were first incubated with thymus extract for 1 hr and subsequently tested for reactivity.