(adv.) Up to this time; hitherto; before; in time past.
Example Sentences:
(1) The heretofore "permanently and totally disabled versus able-bodied" principle in welfare reforms is being abbandoned.
(2) All cases heretofore described in immunocompromised hosts have involved the external auditory canal and mastoid areas.
(3) Heretofore, human tumor clonogenic assays or human glioma-bearing nude mice models were usually used for predicting the drug sensitivity of brain tumor.
(4) It is concluded that the heretofore pessimistic outlook regarding complete quadriplegia is unwarranted and that a more aggressive approach may result in a better functional outcome.
(5) Since basilar artery thrombosis is now a treatable condition, early diagnosis and documentation of functional deficits moves into a more important clinical area than heretofore.
(6) Taken together, these results suggest that processing of alpha-MSH is unlike that heretofore described for other peptide antigens and seems to involve APC handling to form the stimulatory moiety presented on the APC surface.
(7) However, the electrofocusing pattern of renin from pituitary tissue (pI = 4.43, 5.77) differed from that of plasma and kidney enzymes heretofore reported, a discrepancy which could be interpreted as evidence for the endogeneous synthesis of renin in the brain tissue.
(8) The facts that (a) essentially all particles, regardless of orientation, entrap cells, and (b) nonporous particles also entrap cells with high efficiency, indicate that filtration effects are irrelevant and that heretofore unrecognized hydrodynamic forces are alone responsible for the cell immobilization.
(9) Perhaps alpha activation is indicative of stimulating and excitatory effects induced by m-xylene exposure, which has been noted heretofore in the absorption phase of alcohol intake.
(10) The important otolaryngological manifestations of arthrogryposis multiplex congenita (AMC), which heretofore have not been described in otolaryngological and other specialty journals, are reviewed.
(11) Finding the chromosomal location of human genes that heretofore have been defined solely by phenotypes, in particular clinical phenotypes that are transmitted in Mendelian fashion in families, is an early and often crucial step in the process of identifying the molecular basis of a disease.
(12) Tumors of the skull base with carotid artery involvement have heretofore required carotid ligation or been deemed inoperable.
(13) Heteroplasmy, heretofore rarely observed, occurred frequently in these same two regions.
(14) Heretofore, unresolved was the question which skin element causes stimulation of vessel formation in this lesion: the epidermis, the dermis, vessels themselves, inflammatory cells, and so forth.
(15) The induction of experimental allergic encephalomyelitis (EAE) with purified myelin basic protein (MBP) has, heretofore, required its incorporation in a water-in-oil emulsion or adsorption on particulate adjuvants.
(16) These anomalies in trisomy 22 mosaicism have not been emphasized heretofore.
(17) A detailed examination of a stillborn fetus with Apert's syndrome showed several unexpected findings, which prompted a reevaluation of the heretofore generally accepted hypotheses regarding the cause of the dysmorphic craniofacial features in this syndrome.
(18) Today's perspective of the endothelial cell recognizes its real significance, heretofore neglected, and anticipates important future contributions to improved medical management.
(19) Juan Salgado, community leader creating a model for workforce development and training among immigrant communities through a holistic approach that addresses language skills, education and other barriers to entering the workforce Beth Stevens, neuroscientist revealing the heretofore unknown role of microglial cells in neuron communication and prompting a fundamental shift in thinking about brain development in both healthy and unhealthy states.
(20) Multiple pyogenic granuloma-like lesions occurring at punch graft sites are an unusual complication of hair transplantation heretofore unreported.
Whereof
Definition:
(adv.) Of which; of whom; formerly, also, with which; -- used relatively.
(adv.) Of what; -- used interrogatively.
Example Sentences:
(1) Whereof one cannot speak thereof we must pass over in silence and all that.
(2) In token whereof I have hereunto set my hand this tenth day of December, 1936, in the presence of the witnesses whose signatures are subscribed.
(3) The amendment’s first section reads: “Neither slavery nor involuntary servitude, except as a punishment for crime whereof the party shall have been duly convicted, shall exist within the United States, or any place subject to their jurisdiction.” Facebook Twitter Pinterest Donald Trump during a campaign rally in Warren, Michigan, March 2016.
(4) The effect of 21 chemical substances was investigated whereof 7 compounds was determined as effective fading-inhibitors.
(5) Consequently, we conclude, that a policy followed in the serodiagnostic Western-Blot of human AIDS should also be adopted for the interpretation of the EIA Western-Blot, namely to declare as positive merely horse sera which evidence more than one single band, whereof at least one band should represent a viral glycoprotein.
(6) Serwotka, 46, who grew up in the South Wales valleys, knows whereof he speaks: he left school at 16, with five painfully acquired O-levels, and went to work for a benefit office in Aberdare.
(7) The Cainguá (Mbŷá) have preserved a singular theology whereof the comprehension makes possible an approach to the real being within that culture.
(8) Pancreatic enzyme substitution may principally be used in few indications, whereof most of them are only relative.
(9) Treatment was required in 39 cases whereof 18 were placed under observation only.
(10) Consequently, a prospective study of symptoms and endoscopy and biopsy interpretation was undertaken in 200 patients consecutively submitted to upper endoscopy, whereof 12 were excluded.
(11) Stone removal was successful in 82% of the cases whereof the stones were pushed back into the renal pelvis and subsequently managed with percutaneous nephrolithotomy or extracorporeal shock wave lithotripsy in 24%.
(12) Bobbitt, we can assume, knows whereof he speaks: he has shot all three of McQueen's features – Hunger, Shame and now 12 Years a Slave – as well as five of McQueen's gallery shorts, dating back to 2002's Western Deep , shot in South Africa inside the world's deepest gold mine.
(13) Four patients had misalignments of up to 15 degrees, whereof three of them had combined varus-recurvation-angulations without functional or cosmetic sequelae.
(14) The total of 1154 identified samples consisted mainly of ruminants (37%, whereof bushbuck represented 57%), hippopotamus (34%), and monitor lizard (19%).
(15) The title refers to the 13th Amendment to the US Constitution: “Neither slavery nor involuntary servitude, except as a punishment for crime whereof the party shall have been duly convicted, shall exist within the United States.” For the new British black film-making hope, Adesunloye, access to funds and exposure remain the key issues, even with a voguish new transatlantic interest in telling the story of the African diaspora.
(16) Report on 370 dyslexics, whereof 281 can be evaluated.
(17) Iscoms containing the fusion protein of measles virus induced T cell clones in mice whereof one, after adoptive transfer, protected mice against intracerebral challenge infection.
(18) Gillen's character, Petyr Baelish, certainly knows whereof he speaks.