What's the difference between heteromerous and number?
Heteromerous
Definition:
(a.) Unrelated in chemical composition, though similar or indentical in certain other respects; as, borax and augite are homoemorphous, but heteromerous.
(a.) With the parts not corresponding in number.
(a.) Having the femoral artery developed as the principal artery of the leg; -- said of certain birds, as the cotingas and pipras.
(a.) Having five tarsal joints in the anterior and middle legs, but only four in the posterior pair, as the blister beetles and oil beetles.
Example Sentences:
(1) p50B is able to form heteromeric kappa B-binding complexes with RelB, as well as with p65 and p50, the two subunits of NF-kappa B. Transient-transfection experiments in embryonal carcinoma cells demonstrate a functional cooperation between p50B and RelB or p65 in transactivation of a reporter plasmid dependent on a kappa B site.
(2) Thus we conclude that both the dioxin and glucocorticoid receptor can form heteromeric complexes which share a common non-ligand-binding component.
(3) Furthermore, substitution of glutamine for arginine in putative transmembrane segment M2 of the GluR2 subunit makes the heteromeric channels permeable to Ca2+.
(4) Tyrosine phosphorylation acts as a switch to induce the binding of SH2 domains, thereby mediating the formation of heteromeric protein complexes at or near the plasma membrane.
(5) non-DNA binding) 9 S heteromeric complex which contains the Mr approximately 90,000 heat shock protein, hsp90.
(6) Mouse lymphoma cells contain a nonactivated glucocorticoid receptor of Mr approximately 330,000 which is heteromeric in nature and is unable to bind to DNA.
(7) (1984) Biochemistry 23, 1392-1398) that sulfhydryl moieties on the receptor are absolutely required for the receptor to bind to DNA, and they show that the sulfhydryl-modifying reagent does not inhibit the temperature-mediated dissociation of the heteromeric receptor complex that accompanies transformation to the DNA-binding state.
(8) On the basis of these findings, we suggest that subtle changes within the proposed multimerization domain can elicit different effects with the individual Rel-related proteins and that a potential role of p65 delta may be to negatively regulate NF-kappa B function through formation of nonfunctional heteromeric complexes.
(9) Upon expression in cultured cells, the new subunits yielded prominent, typical glutamate- and NMDA-activated currents only when they were in heteromeric configurations with NR1.
(10) Taken together, these observations demonstrate that the steroid-binding domain contains the features required for formation of the 9 S heteromeric complex, and they are consistent with the proposal that the steroid-binding domain normally represses receptor function.
(11) Some in vitro synthesized mineralocorticoid receptor assembles into the heteromeric unactivated form; 2.
(12) We conclude that the large forms of wild-type and nti receptors are heteromeric and contain only one hormone-building polypeptide per complex.
(13) We suggest that TCP1 may represent one of a family of molecules in the eukaryotic cytosol involved in protein folding and regulated in part by their heteromeric associations.
(14) The deduced amino acid sequence of the A chain showed a remarkable identity over a length of 90-amino acid residues with a sequence of the Hap3 polypeptide, a component of a heteromeric multisubunit yeast transcription factor.
(15) Thus, as with gamma-aminobutyric acid, glycine, and nicotinic acetylcholine receptors, native kainate-quisqualate-sensitive glutamate receptors form a family of heteromeric proteins.
(16) Adenovirus infection activates the E2F transcription factor, in part through the formation of a heteromeric protein complex involving a 19 kd E4 gene product that then allows cooperative and stable promoter binding.
(17) The aryl hydrocarbon (Ah) receptor undergoes a ligand-dependent transformation to a heteromeric structure which has the ability to bind DNA sequence-specifically with high affinity.
(18) In hybrids expressing human and rodent ALDH3 no heteromeric isozymes were observed.
(19) Although some of these regulatory principles operate in prokaryotes, the combinatorial nature of the transcriptional activation process, the existence of multiprotein families, and the prevalence of heteromeric protein complexes are characteristic of eukaryotic cells and are essential for the extraordinary complexity of gene expression patterns in multicellular organisms.
(20) The binding of integrin to matrix molecules is sensitive to peptides carrying the cell-binding sequence Arg-Gly-Asp and requires heteromeric integrity.
Number
Definition:
(n.) That which admits of being counted or reckoned; a unit, or an aggregate of units; a numerable aggregate or collection of individuals; an assemblage made up of distinct things expressible by figures.
(n.) A collection of many individuals; a numerous assemblage; a multitude; many.
(n.) A numeral; a word or character denoting a number; as, to put a number on a door.
(n.) Numerousness; multitude.
(n.) The state or quality of being numerable or countable.
(n.) Quantity, regarded as made up of an aggregate of separate things.
(n.) That which is regulated by count; poetic measure, as divisions of time or number of syllables; hence, poetry, verse; -- chiefly used in the plural.
(n.) The distinction of objects, as one, or more than one (in some languages, as one, or two, or more than two), expressed (usually) by a difference in the form of a word; thus, the singular number and the plural number are the names of the forms of a word indicating the objects denoted or referred to by the word as one, or as more than one.
(n.) The measure of the relation between quantities or things of the same kind; that abstract species of quantity which is capable of being expressed by figures; numerical value.
(n.) To count; to reckon; to ascertain the units of; to enumerate.
(n.) To reckon as one of a collection or multitude.
(n.) To give or apply a number or numbers to; to assign the place of in a series by order of number; to designate the place of by a number or numeral; as, to number the houses in a street, or the apartments in a building.
(n.) To amount; to equal in number; to contain; to consist of; as, the army numbers fifty thousand.
Example Sentences:
(1) However, as other patients who lived at the periphery of the Valserine valley do not appear to be related to any patients living in the valley, and because there has been considerable immigration into the valley, a number of hypotheses to explain the distribution of the disease in the region remain possible.
(2) These included bringing in the A* grade, reducing the number of modules from six to four, and a greater attempt to assess the whole course at the end.
(3) When micF was cloned into a high-copy-number plasmid it repressed ompF gene expression, whereas when cloned into a low-copy-number plasmid it did not.
(4) Use of the improved operative technique contributed to reduction in number of complications.
(5) Nutritionally rehabilitated animals had similar numbers of nucleoli to control rats.
(6) Simplicity, high capacity, low cost and label stability, combined with relatively high clinical sensitivity make the method suitable for cost effective screening of large numbers of samples.
(7) The hemodynamic efficiency of the drive was tested in a number of in vivo experiments.
(8) The final number of fibers--140,000-165,000--is reached by the sixth week after birth.
(9) On removal of selective pressure, the His+ phenotype was lost more readily than the Ura+ Trp+ markers, with a corresponding decrease in plasmid copy number.
(10) This article describes a number of syndromes affecting the nail unit.
(11) At the time, with a regular supply of British immigrants arriving in large numbers in Australia, Biggs was able to blend in well as "Terry Cook", a carpenter, so well in fact that his wife, Charmian, was able to join him with his three sons.
(12) Since 1979 there has been an increase of 17,122 in the number of beds available in nursing homes.
(13) Other haematological parameters remained normal, with the exception of the absolute number of lymphocytes, which initially fell sharply but soon returned to, and even exceeded, control levels.
(14) All the twins were born in years 1973-1987, the total number was 2,226 boys and 2,302 girls.
(15) The number of neoplastic cells in each cell suspension was determined by cytologic criteria.
(16) aeruginosa and Enterococci) were significantly reduced in number during the manipulation (Fig.
(17) Because of the small number of patients reported in the world literature and lack of controlled studies, the treatment of small cell carcinoma of the larynx remains controversial; this retrospective analysis suggests that combination chemotherapy plus radiation offers the best chance for cure.
(18) Further, at the end of treatment fewer patients had depressive symptoms and the total daily number of hours of wellbeing and normal movement increased.
(19) The country has no offshore wind farms, though a number of projects are in the research phase to determine their profitability.
(20) Despite a 10-year deadline to have the same number of ethnic minority officers in the ranks as in the populations they serve, the target was missed and police are thousands of officers short.