What's the difference between heteromerous and part?
Heteromerous
Definition:
(a.) Unrelated in chemical composition, though similar or indentical in certain other respects; as, borax and augite are homoemorphous, but heteromerous.
(a.) With the parts not corresponding in number.
(a.) Having the femoral artery developed as the principal artery of the leg; -- said of certain birds, as the cotingas and pipras.
(a.) Having five tarsal joints in the anterior and middle legs, but only four in the posterior pair, as the blister beetles and oil beetles.
Example Sentences:
(1) p50B is able to form heteromeric kappa B-binding complexes with RelB, as well as with p65 and p50, the two subunits of NF-kappa B. Transient-transfection experiments in embryonal carcinoma cells demonstrate a functional cooperation between p50B and RelB or p65 in transactivation of a reporter plasmid dependent on a kappa B site.
(2) Thus we conclude that both the dioxin and glucocorticoid receptor can form heteromeric complexes which share a common non-ligand-binding component.
(3) Furthermore, substitution of glutamine for arginine in putative transmembrane segment M2 of the GluR2 subunit makes the heteromeric channels permeable to Ca2+.
(4) Tyrosine phosphorylation acts as a switch to induce the binding of SH2 domains, thereby mediating the formation of heteromeric protein complexes at or near the plasma membrane.
(5) non-DNA binding) 9 S heteromeric complex which contains the Mr approximately 90,000 heat shock protein, hsp90.
(6) Mouse lymphoma cells contain a nonactivated glucocorticoid receptor of Mr approximately 330,000 which is heteromeric in nature and is unable to bind to DNA.
(7) (1984) Biochemistry 23, 1392-1398) that sulfhydryl moieties on the receptor are absolutely required for the receptor to bind to DNA, and they show that the sulfhydryl-modifying reagent does not inhibit the temperature-mediated dissociation of the heteromeric receptor complex that accompanies transformation to the DNA-binding state.
(8) On the basis of these findings, we suggest that subtle changes within the proposed multimerization domain can elicit different effects with the individual Rel-related proteins and that a potential role of p65 delta may be to negatively regulate NF-kappa B function through formation of nonfunctional heteromeric complexes.
(9) Upon expression in cultured cells, the new subunits yielded prominent, typical glutamate- and NMDA-activated currents only when they were in heteromeric configurations with NR1.
(10) Taken together, these observations demonstrate that the steroid-binding domain contains the features required for formation of the 9 S heteromeric complex, and they are consistent with the proposal that the steroid-binding domain normally represses receptor function.
(11) Some in vitro synthesized mineralocorticoid receptor assembles into the heteromeric unactivated form; 2.
(12) We conclude that the large forms of wild-type and nti receptors are heteromeric and contain only one hormone-building polypeptide per complex.
(13) We suggest that TCP1 may represent one of a family of molecules in the eukaryotic cytosol involved in protein folding and regulated in part by their heteromeric associations.
(14) The deduced amino acid sequence of the A chain showed a remarkable identity over a length of 90-amino acid residues with a sequence of the Hap3 polypeptide, a component of a heteromeric multisubunit yeast transcription factor.
(15) Thus, as with gamma-aminobutyric acid, glycine, and nicotinic acetylcholine receptors, native kainate-quisqualate-sensitive glutamate receptors form a family of heteromeric proteins.
(16) Adenovirus infection activates the E2F transcription factor, in part through the formation of a heteromeric protein complex involving a 19 kd E4 gene product that then allows cooperative and stable promoter binding.
(17) The aryl hydrocarbon (Ah) receptor undergoes a ligand-dependent transformation to a heteromeric structure which has the ability to bind DNA sequence-specifically with high affinity.
(18) In hybrids expressing human and rodent ALDH3 no heteromeric isozymes were observed.
(19) Although some of these regulatory principles operate in prokaryotes, the combinatorial nature of the transcriptional activation process, the existence of multiprotein families, and the prevalence of heteromeric protein complexes are characteristic of eukaryotic cells and are essential for the extraordinary complexity of gene expression patterns in multicellular organisms.
(20) The binding of integrin to matrix molecules is sensitive to peptides carrying the cell-binding sequence Arg-Gly-Asp and requires heteromeric integrity.
Part
Definition:
(n.) One of the portions, equal or unequal, into which anything is divided, or regarded as divided; something less than a whole; a number, quantity, mass, or the like, regarded as going to make up, with others, a larger number, quantity, mass, etc., whether actually separate or not; a piece; a fragment; a fraction; a division; a member; a constituent.
(n.) An equal constituent portion; one of several or many like quantities, numbers, etc., into which anything is divided, or of which it is composed; proportional division or ingredient.
(n.) A constituent portion of a living or spiritual whole; a member; an organ; an essential element.
(n.) A constituent of character or capacity; quality; faculty; talent; -- usually in the plural with a collective sense.
(n.) Quarter; region; district; -- usually in the plural.
(n.) Such portion of any quantity, as when taken a certain number of times, will exactly make that quantity; as, 3 is a part of 12; -- the opposite of multiple. Also, a line or other element of a geometrical figure.
(n.) That which belongs to one, or which is assumed by one, or which falls to one, in a division or apportionment; share; portion; lot; interest; concern; duty; office.
(n.) One of the opposing parties or sides in a conflict or a controversy; a faction.
(n.) A particular character in a drama or a play; an assumed personification; also, the language, actions, and influence of a character or an actor in a play; or, figuratively, in real life. See To act a part, under Act.
(n.) One of the different melodies of a concerted composition, which heard in union compose its harmony; also, the music for each voice or instrument; as, the treble, tenor, or bass part; the violin part, etc.
(n.) To divide; to separate into distinct parts; to break into two or more parts or pieces; to sever.
(n.) To divide into shares; to divide and distribute; to allot; to apportion; to share.
(n.) To separate or disunite; to cause to go apart; to remove from contact or contiguity; to sunder.
(n.) Hence: To hold apart; to stand between; to intervene betwixt, as combatants.
(n.) To separate by a process of extraction, elimination, or secretion; as, to part gold from silver.
(n.) To leave; to quit.
(v. i.) To be broken or divided into parts or pieces; to break; to become separated; to go asunder; as, rope parts; his hair parts in the middle.
(v. i.) To go away; to depart; to take leave; to quit each other; hence, to die; -- often with from.
(v. i.) To perform an act of parting; to relinquish a connection of any kind; -- followed by with or from.
(v. i.) To have a part or share; to partake.
(adv.) Partly; in a measure.
Example Sentences:
(1) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(2) We attribute this in part to early diagnosis by computed tomography (CT), but a contributory factor may be earlier referrals from country centres to a paediatric trauma centre and rapid transfer, by air or road, by medical retrieval teams.
(3) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
(4) These results show that the pathogenic phenotypes of MCF viruses are dissociable from the thymotropic phenotype and depend, at least in part, upon the enhancer sequences.
(5) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(6) Because cystine in medium was converted rapidly to cysteine and cysteinyl-NAC in the presence of NAC and given that cysteine has a higher affinity for uptake by EC than cystine, we conclude that the enhanced uptake of radioactivity was in the form of cysteine and at least part of the stimulatory effect of NAC on EC glutathione was due to a formation of cysteine by a mixed disulfide reaction of NAC with cystine similar to that previously reported for Chinese hamster ovarian cells (R. D. Issels et al.
(7) At operation, the tumour was identified and excised with part of the aneurysmal wall.
(8) However, ticks, which failed to finish their feeding and represent a disproportionately great part of the whole parasite's population, die together with them and the parasitic system quickly restores its stability.
(9) Muscle weakness and atrophy were most marked in the distal parts of the legs, especially in the gastrocnemius and soleus muscles, and then spread to the thighs and gluteal muscles.
(10) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(11) This modulation results from repetitive, alternating bursts of excitatory and inhibitory postsynaptic potentials, which are caused at least in part by synaptic feedback to the command neurons from identified classes of neurons in the feeding network.
(12) Results show diet, self-control and parts of insulin-therapy to be problematic treatment components.
(13) Further analysis with two other synthetic peptides (212Cys to 222Glu and Cys X 221Ile to 236Glu) indicated that the dodecapeptide Ile-Glu-Phe-Gln-Lys-Asn-Asn-Arg-Leu-Leu-Glu mimicked either the whole or a major part of the neutralization epitope.
(14) Schneiderlin, valued at an improbable £27m, and the currently injured Jay Rodriguez are wanted by their former manager Mauricio Pochettino at Spurs, but the chairman Ralph Krueger has apparently called a halt to any more outgoings, saying: “They are part of the core that we have decided to keep at Southampton.” He added: “Jay Rodriguez and Morgan Schneiderlin are not for sale and they will be a part of our club as we enter the new season.” The new manager Ronald Koeman has begun rebuilding by bringing in Dusan Tadic and Graziano Pellè from the Dutch league and Krueger said: “We will have players coming in, we will make transfers to strengthen the squad.
(15) Patrice Evra Evra Handed a five-match international ban for his part in the France squad’s mutiny against Raymond Domenech at the 2010 World Cup, it took Evra almost a year to force his way back in.
(16) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(17) The method is based on two-dimensional scanning photon absorptiometry on the distal part of the forearm.
(18) McDonald said cutting better deals with suppliers and improving efficiency as well as raising some prices had only partly offset the impact of sterling’s fall against the dollar.
(19) A strong block to the elongation of nascent RNA transcripts by RNA polymerase II occurs in the 5' part of the mammalian c-fos proto-oncogene.
(20) Anytime they feel parts of the Basic Law are not up to their current standards of political correctness, they will change it and tell Hong Kong courts to obey.