(1) Based on the fact that all hibernators, at their regulated minimal body temperature, display a uniform turnover rate, related to body weight, the hypothesis is developed that cold tolerance of mammals is generally limited by a common specific minimal metabolic rate, which larger organisms, because of their lower basal metabolism, already attain in less profound hypothermia.
(2) Throughout the hibernation season (October to April), white adipose tissue-saturated FA percentage decreased, monoene percentage remained constant, and diene percentage increased.
(3) The role of cyclic changes of protein synthesis rate in adaptation of cells of hibernating mammals to functioning at various temperatures is discussed.
(4) In this animal, central vasopressin infusion during the winter prevents hibernation.
(5) To clarify the cause of uncoupling of Ca influx through Ca channels and the contractility of the myocardium in hibernating chipmunks, the electromechanical effects of two different internal Ca store inhibitors, caffeine and ryanodine, and a cardiotonic agent, isoprenaline, were investigated in papillary muscles of hibernating animals.
(6) The mechanism(s) regulating the duration of the period of hibernation was considered to be concerned with some aspect of metabolism and probably the same for all three species.
(7) The possible mechanisms in regulation of the respiration rate of mitochondria from liver of hibernating ground squirrels have been investigated.
(8) Does ursodeoxycholic acid (UDC) production protect hibernating species of Ursidae against gallstone disease?
(9) Such responses to equithesin were not observed in the non-hibernating rodent species.
(10) In neurons from other structures (lateral septum, medial preoptic area, hippocampus) in the brain slices of both hibernating and waking ground squirrels, thyrotropin-releasing hormone did not usually affect the level of spontaneous discharges.
(11) Fetal mesencephalic tissue was grafted into the lateral ventricle following pregraft refrigeration in calcium-free magnesium-free buffer at 4 degrees C. Fetal mesencephalic tissue was hibernated for 5, 12, 16, 20, 24, 28, 32 hours (group A, B, C, D, E, F and G, respectively).
(12) We find that during hibernation the marrow cavity of the long bones is filled with lipid deposits interspersed with vascular sinusoids containing mononuclear cells and red blood cells.
(13) Ten milligrams of lyophilized plasma albumin fractions from hibernating ground squirrels, woodchucks, black bears, and polar bears produced similar inhibition, with partial reversal by naloxone.
(14) We studied nutrient absorption across the brush-border membrane in jejunal tissues from active 13-lined ground squirrels and in hibernating squirrels that had not eaten for at least 6 wk.
(15) Plasma ANF of both groups of nonhibernating marmots was significantly higher (P less than 0.01) than that the hibernating group, but there was no difference between nonhibernating males and females.
(16) The CG and associated DB were therefore found to exert antagonistic effects which are responsible for the control of spermatogonial DNA synthesis in hibernating Helix aspersa.
(17) U69593, however, antagonized hibernation induced by HIT in summer active ground squirrels.
(18) Grafted fetal mesencephalic tissue which had been hibernated for 16 hours or less survived well.
(19) Over 60% of the blood CO2 stores accumulated at the beginning of the hibernation bout were released by hyperventilation during the first period, prior to the full development of thermogenesis.
(20) The heart of ground squirrels is covered by a large amount of brown adipose tissue during the whole period of hibernation.
Sleep
Definition:
() imp. of Sleep. Slept.
(v. i.) To take rest by a suspension of the voluntary exercise of the powers of the body and mind, and an apathy of the organs of sense; to slumber.
(v. i.) To be careless, inattentive, or uncouncerned; not to be vigilant; to live thoughtlessly.
(v. i.) To be dead; to lie in the grave.
(v. i.) To be, or appear to be, in repose; to be quiet; to be unemployed, unused, or unagitated; to rest; to lie dormant; as, a question sleeps for the present; the law sleeps.
(v. t.) To be slumbering in; -- followed by a cognate object; as, to sleep a dreamless sleep.
(v. t.) To give sleep to; to furnish with accomodations for sleeping; to lodge.
(v. i.) A natural and healthy, but temporary and periodical, suspension of the functions of the organs of sense, as well as of those of the voluntary and rational soul; that state of the animal in which there is a lessened acuteness of sensory perception, a confusion of ideas, and a loss of mental control, followed by a more or less unconscious state.
Example Sentences:
(1) AEDs may also have differential effects on nighttime sleep.
(2) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
(3) For assessment of clinical status, investigators must rely on the use of standardized instruments for patient self-reporting of fatigue, mood disturbance, functional status, sleep disorder, global well-being, and pain.
(4) We investigated whether these peptides also affect the sleep EEG in humans when given intravenously by comparing polysomnographically the effects of four boluses of (1) placebo, (2) 50 micrograms GHRH or (3) 50 micrograms SRIF administered at 22.00, 23.00, 24.00 and 1.00 h to 7 male controls.
(5) Polygraphic recordings during sleep were performed on 18 elderly persons (age range: 64-100 years).
(6) This was carried out on the healthy subjects for a total of 12 nights without medication (control nights asleep), a total of 12 nights following 40 mg of flucortolone the previous morning, and a total of 6 nights with similar blood sampling when sleep was prevented (control nights awake).
(7) Although temazepam was effective for maintaining sleep with short-term use, there was rapid development of tolerance for this effect with intermediate-term use.
(8) The occurrence of episodes of desaturation during sleep in patients suffering from chronic airflow obstruction is well known.
(9) A lower than normal percentage of REM sleep in these patients was consistent with their retarded intellectual development, which supports current thinking that REM sleep may be a sensitive index of brain function integrity.
(10) Amine metabolites, 5-hydroxyindoleacetic acid (5HIAA), and homovanillic acid (HVA) were not substantially affected by sleep deprivation, although there was a significant interaction of clinical response and direction of 3-methoxy-4-hydroxyphenylglycol (MHPG) change.
(11) Results of sleep sampling under electroencephalographic control of the assessment of GH secretion are comparable to conventional pharmacological studies in terms of efficiency, sensitivity, and percentage false-negatives.
(12) Sleep was defined behaviorally as failure to respond to the faint auditory RT cue.
(13) We have evaluated the action of hypnotics on the sleep-wakefulness cycle in freely implanted rats during their maximally active period because it is easier to estimate the duration of the sedative effect.
(14) However, patients can be taught how to retard the onset of wrinkles by avoiding unprotected sun exposure, unnecessary facial movements, and certain sleeping positions.
(15) The analogy with infant sleep patterns and results of studies of brain function in narcoleptics suggest that forebrain inhibitory processes are more important in narcoleptic symptomology than is brainstem dysfunction.
(16) In short term clinical studies, the beneficial effects of transdermal estradiol on plasma gonadotrophins, maturation of the vaginal epithelium, metabolic parameters of bone resorption and menopausal symptoms (hot flushes, sleep disturbance, genitourinary discomfort and mood alteration) appear to be comparable to those of oral and subcutaneous estrogens, while the undesirable effects of oral estrogens on hepatic metabolism are avoided.
(17) Sleep alterations in addicted newborns could be related to central nervous system (CNS) distress caused by withdrawal.
(18) "Our black, Muslim and Jewish citizens will sleep much less easily now the BBC has legitimised the BNP by treating its racist poison as the views of just another mainstream political party when it is so uniquely evil and dangerous."
(19) Stage REM frequently appeared within 10 min of stage 1 onset and the normal sequence of stages REM and 4 were altered, demonstrating that the organization of sleep within a nap is quite different from that in monophasic nocturnal sleep.
(20) This result is discussed in terms of either a function of time-of-day effect or of prior sleep intensity.