(n.) A tool chiefly for digging up weeds, and arranging the earth about plants in fields and gardens. It is made of a flat blade of iron or steel having an eye or tang by which it is attached to a wooden handle at an acute angle.
(n.) The horned or piked dogfish. See Dogfish.
(v. t.) To cut, dig, scrape, turn, arrange, or clean, with a hoe; as, to hoe the earth in a garden; also, to clear from weeds, or to loosen or arrange the earth about, with a hoe; as, to hoe corn.
(v. i.) To use a hoe; to labor with a hoe.
Example Sentences:
(1) HOE was the most active compound, being able to accelerate PIP2 breakdown at concentrations between 10(-12) and 10(-6) M, while in the case of HEE the effective doses ranged from 10(-11) to 10(-7) M and from 10(-9) to 10(-6) M in the case of HNE.
(2) The coding region for a secreted proteinaceous inhibitor of the human alpha-amylase (tendamistat; HOE 467) was identified by using a synthetic oligonucleotide probe.
(3) A carcinogenicity study with the LH-RH analog buserelin (HOE 766) was conducted in male and female Wistar rats.
(4) They show HOE 077 to be a promising agent for the inhibition of hepatic fibrosis.
(5) S 0885 and HOE 077 inhibit CCl4-induced liver fibrosis in rats, as shown by significantly reduced hydroxyproline content of the liver and improved liver histology.
(6) A double-blind cross-over study of the effects of HOE 760 (histamine H2-receptor blocker) on diazepam pharmacokinetics was conducted in 12 healthy men.
(7) In addition, the stability of the kinin antagonist, Hoe 140, in synovial fluid was compared with that of synthetic bradykinin.
(8) The addition of increasing concentrations of Hoe 760 to the histamine concentration-response curve caused a parallel rightward shift.
(9) However, the effect of intravenous Hoe 490 was only half as intense as that of HB 419 in the first hours after treatment and the effect of oral Hoe 490 was initially stronger and thereafter temporarily distinctly weaker than that of HB 419.
(10) Studies on absorption and distribution in both skin and organism, as well as on elimination and biotransformation were performed in rats, pigs, and rabbits following topical application of the corticoid prednisolone-17-ethyl carbonate-21-propionate (prednicarbate; test name: Hoe 777), which had been labeled with 14C in position 4 for this purpose.
(11) Mode of action studies were made with Hoe 296, a new synthetic antimycotic, mainly in Candida albicans.
(12) Treatment with ramipril plus the BK B2-receptor antagonist HOE 140 for 6 weeks significantly attenuated the antihypertensive effects of the ACE-inhibitor in 2K1C hypertensive WI rats, but not in 2K1C hypertensive BN-K rats and in SHR.
(13) Partial inhibition by relatively high concentrations of Hoe 296 of the respiratory activity of yeast cells or mitochondria therefrom with exogenous substrates can be explained by decreased uptake of the substrates from the medium.
(14) HOE 077 wa rapidly and completely absorbed after oral administration.
(15) Hoe 065 prevented the disruption of memory induced by scopolamine administered before training.
(16) Preincubation of the detector cells with Hoe 140 completely abolished this nitric oxide release.
(17) The organ distribution of the 125I-labelled (3-9)-heptapeptide fragments was similar to LH-RH, but not to Hoe 766.
(18) The decrease of cardiac activity in Rhesus monkeys amounted to 69% in 24 h, whereas proscillaridin A decreased cardiac activity only by 41% in 24 h. The absorption of HOE 040 from the duodenum of dogs anesthetized with pentobarbital amounted to 72%, whereas proscillaridin A is observed by only between 14 and 25%.
(19) We have developed a neutral human insulin (Hoe 21 GH) which is stabilized for use in implantable roller pumps.
(20) A radioimmunoassay for HOE 766 was developed using 125I[D-Trp6,Des-Gly10]GnRH ethylamide as tracer and an antiserum raised against HOE 766.
Tool
Definition:
(n.) An instrument such as a hammer, saw, plane, file, and the like, used in the manual arts, to facilitate mechanical operations; any instrument used by a craftsman or laborer at his work; an implement; as, the tools of a joiner, smith, shoe-maker, etc.; also, a cutter, chisel, or other part of an instrument or machine that dresses work.
(n.) A machine for cutting or shaping materials; -- also called machine tool.
(n.) Hence, any instrument of use or service.
(n.) A weapon.
(n.) A person used as an instrument by another person; -- a word of reproach; as, men of intrigue have their tools, by whose agency they accomplish their purposes.
(v. t.) To shape, form, or finish with a tool.
(v. t.) To drive, as a coach.
Example Sentences:
(1) Spectral analysis of spontaneous heart rate fluctuations, a powerful noninvasive tool for quantifying autonomic nervous system activity, was assessed in Xenopus Laevis, intact or spinalized, at different temperatures and by use of pharmacological tools.
(2) The HTCA is promising as a potential tool for studying the biology of tumors.
(3) But both for malaria and Aids we’re seeing the tools that will let us do 95-100% reduction.
(4) These studies demonstrate the potential of ICAM-1 transfectants as tools for analysis of the role of ICAM-1 in lymphoid adhesion.
(5) This method can characterize reliably flavivirus field isolates at the molecular level without extensive virus propagation and molecular cloning, and will be a valuable tool for molecular epidemiological studies.
(6) The basic principle of the resonant tool, its adaptation for surgery, the experimental results of its use in animals, and clinical experience are reported.
(7) Colloidal gold immuno-electron microscopy is a powerful tool for defining antigenicity at the subcellular level.
(8) A diversity of serogroups and toxigenicity was a general finding, however, strains found in the proximal gut were also cultured from the rectum, indicating that faecal specimens would be a valid tool in investigating the role of these organisms in SIDS cases compared with healthy controls.
(9) SR 42128 is a potent and long-acting tool for studying the role of the renin angiotensin system in primates and humans.
(10) In this study we propose a method for the analysis of the relationship between heart rate changes and respiration as a possible diagnostic tool for cardiac autonomic damage.
(11) However LHRH agonists alone or in combination with ovarian steroids are of potential value as a research tool.
(12) These findings demonstrate that heteroantisera can provide an additional important tool for dissecting the heterogeneity of T-cell leukemias and for relating them to more differentiated normal T cells.
(13) This model provides a standard nonoperative approach for the induction of intestinal ischemia in dogs and could be a valuable tool in the study of intestinal ischemia.
(14) Before we embark on the next steps of the global technological revolution, we must ensure that the most basic of online tools are accessible to all.
(15) This ion-selective microelectrode may show promise as a useful tool for the determination of intracellular bile salt activity.
(16) Axotomy should be a useful tool for determining which other neurotransmitter receptors are produced by facial motoneurons and efferent neurons in other cranial nerve nuclei.
(17) Given that patient preferences constitute a central concept within the framework of HRQL, further empirical evaluation of utility measures of preference is fundamental to improving the HRQL measurement tool-kit.
(18) This study also demonstrates that pulsed-field gel electrophoresis is a powerful new tool for the analysis of human chromosomal translocations.
(19) In order to maximize the utility of these tools a high degree of reliability is essential.
(20) Extraction tools included flexible, telescoping sheaths advanced over the lead to dilate scar tissue and apply countertraction, deflection catheters, and wire basket snares.