(superl.) Having much sensible heat; exciting the feeling of warmth in a great degree; very warm; -- opposed to cold, and exceeding warm in degree; as, a hot stove; hot water or air.
(superl.) Characterized by heat, ardor, or animation; easily excited; firely; vehement; passionate; violent; eager.
(superl.) Lustful; lewd; lecherous.
(superl.) Acrid; biting; pungent; as, hot as mustard.
() of Hote
() of Hote
Example Sentences:
(1) In the bars of Antwerp and the cafes of Bruges, the talk is less of Christmas markets and hot chocolate than of the rising cost of financing a national debt which stands at 100% of annual national income.
(2) The analgesic activity of morphine was assessed by the hot-plate technique in the offspring of female CFE rats that had received morphine twice daily on days 5 to 12 of pregnancy.
(3) The data indicate that hot flashes may start much earlier and continue far longer than is commonly recognized by physicians or acknowledged in textbooks of gynecology.
(4) The phage is also thermostable in water of the hot spring from which this phage was isolated.
(5) In short term clinical studies, the beneficial effects of transdermal estradiol on plasma gonadotrophins, maturation of the vaginal epithelium, metabolic parameters of bone resorption and menopausal symptoms (hot flushes, sleep disturbance, genitourinary discomfort and mood alteration) appear to be comparable to those of oral and subcutaneous estrogens, while the undesirable effects of oral estrogens on hepatic metabolism are avoided.
(6) "The government should be doing all it can to put the UK at the forefront of this energy revolution not blowing hot and cold on the issue.
(7) It took years of prep work to make this sort of Übermensch thing socially acceptable, let alone hot – lots of “legalize it!” and “you are economic supermen!” appeals to the balled-and-entitled toddler-fists of the sociopathic libertechian madding crowd to really get mechanized mass-death neo-fascism taken mainstream .
(8) To test the hypothesis that EAA agonists are involved in transmission of nociceptive information in the spinal cord, we tested the effect of various opioid, sigma and phencyclidine compounds on the action of NMDA in the tail-flick, hot-plate and biting and scratching nociceptive tests.
(9) Antinociception was studied by measuring tail-flick response to hot (55 degrees C) water.
(10) We had hoped to be back in by now but there was a problem with the hot water.
(11) The expansion comes hot on the heels of another year of stellar growth in which Primark edged closer to overtaking high street stalwart M&S in sales and profits.
(12) A grassed roof, solar panels to provide hot water, a small lake to catch rainwater which is then recycled, timber cladding for insulation ... even the pitch and floodlights are "deliberately positioned below the level of the surrounding terrain in order to reduce noise and light pollution for the neighbouring population".
(13) The influence of hot and dry climate and nutritional status on dry eye incidence is discussed.
(14) Spoon over the dressing and eat immediately, while the tomatoes are still hot and the bread is crisp.
(15) "The rise in those who are self-employed is good news, but the reality is that those who have turned to freelance work in order to pull themselves out of unemployment and those who have decided to work for themselves face a challenging tax maze that could land them in hot water should they get it wrong," says Chas Roy-Chowdhury, head of taxation at the Association of Certified Chartered Accountants.
(16) Writhing response was more influenced after systemic administration of drugs while hot plate latencies was not.
(17) Illness was also significantly associated with eating lightly cooked eggs (unmatched p = 0.02), but not soft boiled eggs, and precooked hot chicken (matched p = 0.006).
(18) Gamma spectra were measured and activities of the detected isotopes were analyzed for 206 high-activity particles (hot particles, HPs) found in northeastern Poland after the Chernobyl accident.
(19) A hot spot in the lung emboli was visualized in two cases.
(20) Every time we have a negotiation, the bidding process (for the project) slows and postpones things.” Water quality has become a hot-button issue as the Olympics draw closer with little sign of progress in cleaning up the fetid bay, as well as the lagoon system in western Rio that hugs the sites of the Olympic park, the very heart of the games.
Hox
Definition:
(v. t.) To hock; to hamstring. See Hock.
Example Sentences:
(1) In a previous analysis of the Hox-1.1 promoter in transgenic mice, we identified sequences that were sufficient to establish transgene expression in a specific region of the embryo.
(2) Thus, Hox-1.6 is involved in regional specification along the rostrocaudal axis, but only in its most rostral domain of expression.
(3) The mouse Hox 2.1 gene contains a homeobox sequence and is therefore a candidate for a vertebrate gene involved in the control of embryonic patterning or positional specification.
(4) The results show that the Hox 2.1 gene produces at least two related phosphorylated proteins present in different proportions in different tissues.
(5) Two of the hox appear to be cognates of the human Hu-1 (or mouse Hox 2.1) and the mouse Hox 1-3, while another is closely related to the mouse Hox 1-4.
(6) The expression of the eleven HOX 1 genes is lineage-restricted and these genes are predominantly detected within cells of myelomonocytic origin.
(7) Our analysis of Hox 1.3 cDNA and genomic clones indicates that the gene is organized into two exons and encodes a 270-amino-acid homeo domain protein.
(8) Southern blotting shows that the DNA sequence encoding Hox-6.1 is single copy.
(9) A 2.4 kb RNA encoded by the murine Hox 1.1 (m6) homeobox gene is induced when F9 stem cells are differentiated with retinoic acid and dibutyryl cyclic AMP.
(10) This report demonstrates that the genes in the murine Hox-2 cluster display spatially and temporally dynamic patterns of expression in the transverse plane of the developing CNS.
(11) The early transcription pattern thus appears to be compatible with a regionalizing role for the Hox-3.1 gene.
(12) Here we show correct regulation by Hox-1.1 sequences in transgenic mice and identify the elements responsible for different levels of control.
(13) The resulting Hox-2.2 misexpression produces early postnatal lethality as well as craniofacial and axial skeletal perturbations that include open eyes at birth, cleft palate, micrognathia, microtia, skull bone deficiencies, and structural and positional alterations in the vertebral column.
(14) This article reviews recent studies on the expression of the homeobox gene, Hox 2.1, during mouse embryogenesis, using the technique of in situ hybridization.
(15) In situ hybridization shows that Hox 2.1 transcripts are regionally localized in the spinal cord in an apparent anterior-posterior gradient extending from the hind brain.
(16) In this review we have built a case for abnormal Hox gene expression in human congenital malformations without presenting any direct evidence of their involvement.
(17) Hox 2.3 was also super-induced by serum, in the presence of cycloheximide, in cells rested previously in serum-free media, suggesting that new protein synthesis was not required for expressive augmentation.
(18) To further understand their regulation, the genomic loci of four newt HBox genes (two from the human HBox (HOX)-2 complex and two from the HOX-3 complex) were analysed and compared with homologous loci in other vertebrates.
(19) DNase I protection of the Hox-1.3 gene promoter region with the Hox-1.3 protein identifies a binding site 144 bp upstream from the start of transcription.
(20) The homeodomain is identical to the genomic sequence for Hox 1H, a newly identified member of the Hox 1 locus (Acampora et al.