(superl.) Having much sensible heat; exciting the feeling of warmth in a great degree; very warm; -- opposed to cold, and exceeding warm in degree; as, a hot stove; hot water or air.
(superl.) Characterized by heat, ardor, or animation; easily excited; firely; vehement; passionate; violent; eager.
(superl.) Lustful; lewd; lecherous.
(superl.) Acrid; biting; pungent; as, hot as mustard.
() of Hote
() of Hote
Example Sentences:
(1) In the bars of Antwerp and the cafes of Bruges, the talk is less of Christmas markets and hot chocolate than of the rising cost of financing a national debt which stands at 100% of annual national income.
(2) The analgesic activity of morphine was assessed by the hot-plate technique in the offspring of female CFE rats that had received morphine twice daily on days 5 to 12 of pregnancy.
(3) The data indicate that hot flashes may start much earlier and continue far longer than is commonly recognized by physicians or acknowledged in textbooks of gynecology.
(4) The phage is also thermostable in water of the hot spring from which this phage was isolated.
(5) In short term clinical studies, the beneficial effects of transdermal estradiol on plasma gonadotrophins, maturation of the vaginal epithelium, metabolic parameters of bone resorption and menopausal symptoms (hot flushes, sleep disturbance, genitourinary discomfort and mood alteration) appear to be comparable to those of oral and subcutaneous estrogens, while the undesirable effects of oral estrogens on hepatic metabolism are avoided.
(6) "The government should be doing all it can to put the UK at the forefront of this energy revolution not blowing hot and cold on the issue.
(7) It took years of prep work to make this sort of Übermensch thing socially acceptable, let alone hot – lots of “legalize it!” and “you are economic supermen!” appeals to the balled-and-entitled toddler-fists of the sociopathic libertechian madding crowd to really get mechanized mass-death neo-fascism taken mainstream .
(8) To test the hypothesis that EAA agonists are involved in transmission of nociceptive information in the spinal cord, we tested the effect of various opioid, sigma and phencyclidine compounds on the action of NMDA in the tail-flick, hot-plate and biting and scratching nociceptive tests.
(9) Antinociception was studied by measuring tail-flick response to hot (55 degrees C) water.
(10) We had hoped to be back in by now but there was a problem with the hot water.
(11) The expansion comes hot on the heels of another year of stellar growth in which Primark edged closer to overtaking high street stalwart M&S in sales and profits.
(12) A grassed roof, solar panels to provide hot water, a small lake to catch rainwater which is then recycled, timber cladding for insulation ... even the pitch and floodlights are "deliberately positioned below the level of the surrounding terrain in order to reduce noise and light pollution for the neighbouring population".
(13) The influence of hot and dry climate and nutritional status on dry eye incidence is discussed.
(14) Spoon over the dressing and eat immediately, while the tomatoes are still hot and the bread is crisp.
(15) "The rise in those who are self-employed is good news, but the reality is that those who have turned to freelance work in order to pull themselves out of unemployment and those who have decided to work for themselves face a challenging tax maze that could land them in hot water should they get it wrong," says Chas Roy-Chowdhury, head of taxation at the Association of Certified Chartered Accountants.
(16) Writhing response was more influenced after systemic administration of drugs while hot plate latencies was not.
(17) Illness was also significantly associated with eating lightly cooked eggs (unmatched p = 0.02), but not soft boiled eggs, and precooked hot chicken (matched p = 0.006).
(18) Gamma spectra were measured and activities of the detected isotopes were analyzed for 206 high-activity particles (hot particles, HPs) found in northeastern Poland after the Chernobyl accident.
(19) A hot spot in the lung emboli was visualized in two cases.
(20) Every time we have a negotiation, the bidding process (for the project) slows and postpones things.” Water quality has become a hot-button issue as the Olympics draw closer with little sign of progress in cleaning up the fetid bay, as well as the lagoon system in western Rio that hugs the sites of the Olympic park, the very heart of the games.
Icy
Definition:
(superl.) Pertaining to, resembling, or abounding in, ice; cold; frosty.
(superl.) Characterized by coldness, as of manner, influence, etc.; chilling; frigid; cold.
Example Sentences:
(1) The dog and the pig also have an endoperoxide-sensitive constrictor system activated by the 11,9-(epoxymethano) analogue of PGH2 and, of particular note, ICI 79939 and its 11-oxo analogue.
(2) The second experiments entailed use of the nonspecific opiate antagonist, naloxone, as well as the specific delta antagonist, ICI 154,129, against seizures induced by icv-administered morphine, morphiceptin, DADL, or DSLET.
(3) Leading clinical candidates have emerged from Smith Kline and French, Lilly, Merck-Frosst, ICI-Stuart and other groups.
(4) ICI 74 205, a synthetic analogue of prostaglandin F2 alpha (PGF2a) with an alkyl side chain extended by an ethyl group, was administered intravenously in 6 patients using normal saline as the vehicle.
(5) However, the pressor response to the stressors was greater in ICI 118,551- than vehicle-treated F1, but the tachycardia was equivalent for both groups.
(6) Rapid cellular uptake and metabolism of polyglutamate forms that are approximately 100-fold more potent as inhibitors of TS can translate a modest TS inhibitor such as ICI D1694 into a very potent inhibitor of cell growth (approximately 500- and approximately 10-fold more potent than CB3717 or ICI 198583, respectively).
(7) Naloxone affected CS levels in control mice and appeared to reduce the CS response to stress: ICI 154,129 and ICI 174,864 did not produce consistent effects on plasma CS levels.
(8) Treatment of hamsters with the same protocol and doses of ICI 200,880 for 8 wk prevented the destructive lesion induced by a single intratracheal dose of HNE.
(9) Tamoxifen (ICI 46474) is the trans-isomer of 1(p-beta-dimethylaminoethoxy-phenyl)-1, 2-diphenylbut-1-ene.
(10) However, with 50 nM ICI 118551 there was a reduction in the maximum response to isoprenaline.
(11) The effect of methallibure (ICI 33828) on spermatogenesis was studied in the gerbil, hedgehog, and mouse.
(12) The two LTD4 receptor antagonists (MK-571 and ICI-204,219) significantly reduced the permeability changes induced by indomethacin, while the two LTB4 antagonists (SC-41930 and LY-255,283) were without significant effect.
(13) Using a double-blind, placebo-controlled crossover design, we tested the hypothesis that the LTD4 receptor antagonist, ICI 204,219, could inhibit LTD4-induced bronchoconstriction in normal subjects.
(14) However, a glutamate antagonist (MK801) and three serotonin antagonists (ritanserin, ketanserin and ICI 170,809) were all unable to alter the MPTP effects, at the doses used in our study.
(15) However, the ICI-ER complexes that remain are in sufficient quantity to bind to gene activation reporter constructs, and in these cells, ICI still behaves as a pure antagonist of gene transcription and does not activate reporter genes.
(16) Only ICI 111,581 (5 mg kg-1) and propranolol (1 and 10 mg kg-1) prolonged P-R interval.
(17) After 7 injections of Zoladex Depot (ICI Pharma, Heidelberg, Germany), the uterus was reduced to normal size carrying dorsally a myoma of the same size.
(18) Pulse-chase experiments indicate that the half-life of the receptor is reduced from approximately 5 hr in the presence of estradiol to less than 1 hr by ICI 164,384.
(19) Plasma concentrations of AUC for ICI 169, 369 were low.
(20) The compound ICI 164,384 [N-n-butyl-N-methyl-11-(3,17 beta-dihydroxyoestra-1,3,5(10)-trien-7 alpha-yl) undecamide] was entirely devoid of oestrogenic activity in the rat and mouse uterus but completely blocked the uterine stimulatory effects of oestradiol and of tamoxifen.