(a.) Having the quality of producing sleep; tending to produce sleep; soporific.
(a.) Of or pertaining to hypnotism; in a state of hypnotism; liable to hypnotism; as, a hypnotic condition.
(n.) Any agent that produces, or tends to produce, sleep; an opiate; a soporific; a narcotic.
(n.) A person who exhibits the phenomena of, or is subject to, hypnotism.
Example Sentences:
(1) Open field behaviors and isolation-induced aggression were reduced by anxiolytics, at doses which may be within the sedative-hypnotic range.
(2) We have evaluated the action of hypnotics on the sleep-wakefulness cycle in freely implanted rats during their maximally active period because it is easier to estimate the duration of the sedative effect.
(3) The pharmacological examination showed that the new compounds are deprived of the hypnotic activity characteristic for 3,3'-spirobi-5-methyltetrahydrofuranone-2 (2) and behaved in most tests as tranquillizers.
(4) to avoid inhibition of 'natural' responses by anxiety due to the laboratory setting, we made use of post-hypnotic suggestions regarding the nature of the stimuli the subjects were to expect.
(5) 3 alpha-hydroxylated pregnane steroids have been shown to possess anesthetic, hypnotic, anticonvulsant and anxiolytic properties.
(6) Non-benzodiazepine hypnotics may be useful alternatives and our group has undertaken double-blind comparative trials with two such compounds, namely zopiclone and zolpidem.
(7) Thus, with its 'intermediate' elimination half-life, loprazolam would appear to have some potential advantages over both long- and short-acting hypnotics in selected patients, although further studies are needed to fully elucidate its place in therapy.
(8) On the other hand, thiazolidone derivatives are reported to have anesthetic, anticonvulsant, and hypnotic activity.
(9) The most thorough and clinically relevant approach to hypnotic drug evaluation is one that balances the strengths and weaknesses of clinical trials and sleep laboratory evaluations.
(10) Contrary to other studies, central nervous system stimulants are not the most widely prescribed psychoactive drugs in childhood and adolescence, but rather, minor tranquilizers, sedatives and hypnotics are the most widely prescribed psychoactive drugs.
(11) Erickson's utilization approach provides a model of hypnotic and strategic intervention for persons seeking psychotherapy because of sexual orientation confusion.
(12) Previously, we demonstrated that dexmedetomidine, an alpha 2 agonist, produces a hypnotic-anesthetic response in rats via activation of central alpha 2 adrenoceptors and that this response could be enhanced by the alpha 1 antagonist prazosin.
(13) Ten kinds of uracil derivatives showed hypnotic activity.
(14) We suggest that GHB may serve as the prototype for a new class of hypnotic compounds derived from natural sources and capable of activating the neurological mechanisms of normal human sleep.
(15) The steroid anesthetic alphaxalone and a series of naturally occurring analogs were compared in potency and efficacy with each other and the hypnotic barbiturate pentobarbital for interaction with gamma-aminobutyric acid (GABA) receptors:binding sites in rat brain membranes and functional activity in 36Cl- flux measurements with rat hippocampal slices.
(16) An attempt was made to construct and validate a questionnaire measure of hypnotic-like experiences based on Shor's (1979) 8-dimension phenomenological analysis of hypnosis.
(17) The literature on the effects of anxiolytic and hypnotic drugs on performance in tasks requiring sustained attention is confusing.
(18) The largest group of insomniac subjects, and the group who most often used hypnotics "frequently and chronically", were women 45 years and older.
(19) Bilateral microinjection of ethanol to the preoptic area of rats causes a dose-dependent hypnotic effect at doses that do not affect brain temperature.
(20) The Hypnotic Induction Profile (HIP) will be discussed as a rapid and efficient method to identify individual resources and develop treatment strategies.
Sleep
Definition:
() imp. of Sleep. Slept.
(v. i.) To take rest by a suspension of the voluntary exercise of the powers of the body and mind, and an apathy of the organs of sense; to slumber.
(v. i.) To be careless, inattentive, or uncouncerned; not to be vigilant; to live thoughtlessly.
(v. i.) To be dead; to lie in the grave.
(v. i.) To be, or appear to be, in repose; to be quiet; to be unemployed, unused, or unagitated; to rest; to lie dormant; as, a question sleeps for the present; the law sleeps.
(v. t.) To be slumbering in; -- followed by a cognate object; as, to sleep a dreamless sleep.
(v. t.) To give sleep to; to furnish with accomodations for sleeping; to lodge.
(v. i.) A natural and healthy, but temporary and periodical, suspension of the functions of the organs of sense, as well as of those of the voluntary and rational soul; that state of the animal in which there is a lessened acuteness of sensory perception, a confusion of ideas, and a loss of mental control, followed by a more or less unconscious state.
Example Sentences:
(1) AEDs may also have differential effects on nighttime sleep.
(2) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
(3) For assessment of clinical status, investigators must rely on the use of standardized instruments for patient self-reporting of fatigue, mood disturbance, functional status, sleep disorder, global well-being, and pain.
(4) We investigated whether these peptides also affect the sleep EEG in humans when given intravenously by comparing polysomnographically the effects of four boluses of (1) placebo, (2) 50 micrograms GHRH or (3) 50 micrograms SRIF administered at 22.00, 23.00, 24.00 and 1.00 h to 7 male controls.
(5) Polygraphic recordings during sleep were performed on 18 elderly persons (age range: 64-100 years).
(6) This was carried out on the healthy subjects for a total of 12 nights without medication (control nights asleep), a total of 12 nights following 40 mg of flucortolone the previous morning, and a total of 6 nights with similar blood sampling when sleep was prevented (control nights awake).
(7) Although temazepam was effective for maintaining sleep with short-term use, there was rapid development of tolerance for this effect with intermediate-term use.
(8) The occurrence of episodes of desaturation during sleep in patients suffering from chronic airflow obstruction is well known.
(9) A lower than normal percentage of REM sleep in these patients was consistent with their retarded intellectual development, which supports current thinking that REM sleep may be a sensitive index of brain function integrity.
(10) Amine metabolites, 5-hydroxyindoleacetic acid (5HIAA), and homovanillic acid (HVA) were not substantially affected by sleep deprivation, although there was a significant interaction of clinical response and direction of 3-methoxy-4-hydroxyphenylglycol (MHPG) change.
(11) Results of sleep sampling under electroencephalographic control of the assessment of GH secretion are comparable to conventional pharmacological studies in terms of efficiency, sensitivity, and percentage false-negatives.
(12) Sleep was defined behaviorally as failure to respond to the faint auditory RT cue.
(13) We have evaluated the action of hypnotics on the sleep-wakefulness cycle in freely implanted rats during their maximally active period because it is easier to estimate the duration of the sedative effect.
(14) However, patients can be taught how to retard the onset of wrinkles by avoiding unprotected sun exposure, unnecessary facial movements, and certain sleeping positions.
(15) The analogy with infant sleep patterns and results of studies of brain function in narcoleptics suggest that forebrain inhibitory processes are more important in narcoleptic symptomology than is brainstem dysfunction.
(16) In short term clinical studies, the beneficial effects of transdermal estradiol on plasma gonadotrophins, maturation of the vaginal epithelium, metabolic parameters of bone resorption and menopausal symptoms (hot flushes, sleep disturbance, genitourinary discomfort and mood alteration) appear to be comparable to those of oral and subcutaneous estrogens, while the undesirable effects of oral estrogens on hepatic metabolism are avoided.
(17) Sleep alterations in addicted newborns could be related to central nervous system (CNS) distress caused by withdrawal.
(18) "Our black, Muslim and Jewish citizens will sleep much less easily now the BBC has legitimised the BNP by treating its racist poison as the views of just another mainstream political party when it is so uniquely evil and dangerous."
(19) Stage REM frequently appeared within 10 min of stage 1 onset and the normal sequence of stages REM and 4 were altered, demonstrating that the organization of sleep within a nap is quite different from that in monophasic nocturnal sleep.
(20) This result is discussed in terms of either a function of time-of-day effect or of prior sleep intensity.