(a.) Having the quality of producing sleep; tending to produce sleep; soporific.
(a.) Of or pertaining to hypnotism; in a state of hypnotism; liable to hypnotism; as, a hypnotic condition.
(n.) Any agent that produces, or tends to produce, sleep; an opiate; a soporific; a narcotic.
(n.) A person who exhibits the phenomena of, or is subject to, hypnotism.
Example Sentences:
(1) Open field behaviors and isolation-induced aggression were reduced by anxiolytics, at doses which may be within the sedative-hypnotic range.
(2) We have evaluated the action of hypnotics on the sleep-wakefulness cycle in freely implanted rats during their maximally active period because it is easier to estimate the duration of the sedative effect.
(3) The pharmacological examination showed that the new compounds are deprived of the hypnotic activity characteristic for 3,3'-spirobi-5-methyltetrahydrofuranone-2 (2) and behaved in most tests as tranquillizers.
(4) to avoid inhibition of 'natural' responses by anxiety due to the laboratory setting, we made use of post-hypnotic suggestions regarding the nature of the stimuli the subjects were to expect.
(5) 3 alpha-hydroxylated pregnane steroids have been shown to possess anesthetic, hypnotic, anticonvulsant and anxiolytic properties.
(6) Non-benzodiazepine hypnotics may be useful alternatives and our group has undertaken double-blind comparative trials with two such compounds, namely zopiclone and zolpidem.
(7) Thus, with its 'intermediate' elimination half-life, loprazolam would appear to have some potential advantages over both long- and short-acting hypnotics in selected patients, although further studies are needed to fully elucidate its place in therapy.
(8) On the other hand, thiazolidone derivatives are reported to have anesthetic, anticonvulsant, and hypnotic activity.
(9) The most thorough and clinically relevant approach to hypnotic drug evaluation is one that balances the strengths and weaknesses of clinical trials and sleep laboratory evaluations.
(10) Contrary to other studies, central nervous system stimulants are not the most widely prescribed psychoactive drugs in childhood and adolescence, but rather, minor tranquilizers, sedatives and hypnotics are the most widely prescribed psychoactive drugs.
(11) Erickson's utilization approach provides a model of hypnotic and strategic intervention for persons seeking psychotherapy because of sexual orientation confusion.
(12) Previously, we demonstrated that dexmedetomidine, an alpha 2 agonist, produces a hypnotic-anesthetic response in rats via activation of central alpha 2 adrenoceptors and that this response could be enhanced by the alpha 1 antagonist prazosin.
(13) Ten kinds of uracil derivatives showed hypnotic activity.
(14) We suggest that GHB may serve as the prototype for a new class of hypnotic compounds derived from natural sources and capable of activating the neurological mechanisms of normal human sleep.
(15) The steroid anesthetic alphaxalone and a series of naturally occurring analogs were compared in potency and efficacy with each other and the hypnotic barbiturate pentobarbital for interaction with gamma-aminobutyric acid (GABA) receptors:binding sites in rat brain membranes and functional activity in 36Cl- flux measurements with rat hippocampal slices.
(16) An attempt was made to construct and validate a questionnaire measure of hypnotic-like experiences based on Shor's (1979) 8-dimension phenomenological analysis of hypnosis.
(17) The literature on the effects of anxiolytic and hypnotic drugs on performance in tasks requiring sustained attention is confusing.
(18) The largest group of insomniac subjects, and the group who most often used hypnotics "frequently and chronically", were women 45 years and older.
(19) Bilateral microinjection of ethanol to the preoptic area of rats causes a dose-dependent hypnotic effect at doses that do not affect brain temperature.
(20) The Hypnotic Induction Profile (HIP) will be discussed as a rapid and efficient method to identify individual resources and develop treatment strategies.
Soporific
Definition:
(a.) Causing sleep; tending to cause sleep; soporiferous; as, the soporific virtues of opium.
(n.) A medicine, drug, plant, or other agent that has the quality of inducing sleep; a narcotic.
Example Sentences:
(1) The maximum soporific effect did not occur until 90-120 s after injection.
(2) His answer threatened a soporific summer-long contest that would expose a great gap between the self-styled people's party and the people themselves.
(3) 'P ublic sector commissioning": I can't think of a phrase that conveys something so important and yet sounds so soporific.
(4) Soporific effect of hexenal was distinctly increased in the burns, which correlated to the severity of thermic impairment.
(5) Pebble-dashed walls, red roof tiles, Velux windows, cherry trees... these things make me think not of daring strokes of oil on canvas, but of the safe, the soporific - a round of golf, perhaps, or a gentle Sunday-night sitcom.
(6) Less drugs were used in general, and the use of tranquillizers and soporifics was cut down to a third.
(7) Higher doses of naloxone (1Opmol into the LC) were however, required to antagonize the behavioural and ECoG soporific effects induced by the Kappa-receptor agonist U 50,488H.
(8) The drug is well tolerated by the patients and does not produce any inhibitory or soporific action.
(9) And, intriguingly, a 2009 study at Mashhad University in Iran revealed an extract of saffron did have soporific qualities, on mice at least.
(10) Instead, the atmosphere is soporific, with an underlying threat of menace.
(11) Toxicological urine analysis for drugs--directed mainly at soporifics, sedatives, tranquilizers, and pain-relievers--on 84 patients involved in industrial accidents yielded the following results.
(12) What had been a sombre occasion for City fans as they looked at an Etihad Stadium dugout without Mancini for a first time since December 2009 became further muted when a soporific start to the game had ended with Anthony Pilkington opening the scoring for Norwich.
(13) 1 Experiments were performed on a variety of tissues from different species to establish whether or not the properties of p-chlorophenylalanine methyl ester (PCPA) included a 5-hydroxytryptamine (5-HT)-like action which might explain the soporific action of PCPA in chicks.
(14) Because of their pharmacologic action, alcohol and high doses of soporifics used as remedies may produce REM-deficit sleep and actually prolong insomnia.
(15) Imagine my surprise in the morning to find it was gone 7am – the soporific effect of the loud snoring made my baby sleep through the night for the first time!
(16) Long sleep (LS) and short sleep (SS) mice have a differential sensitivity to the behavioral actions of an adenosine agonist, R-phenylisopropyl-adenosine (PIA) that parallels their differential sensitivity to the soporific effects of ethanol.
(17) If so, the soporific way Per Mertesacker dawdled in possession and Kieran Gibbs clumsily punted the ball into the air suggested there had been scant impact.
(18) After 53 days of alcohol ingestion there was no evidence of tolerance to the soporific effects of parenterally administered ethanol and removal of the ethanol solutions failed to produce any signs of alcohol withdrawal.
(19) Further, much evidence also supports the conclusion that most of these hypnotic-depressants and anesthetics could exert their soporific influence by a potentiation of GABA activity.
(20) Recent evidence, as well as reevaluated previous evidence, indicates that Long-Sleep mice are more sensitive to the soporific effects of three major classes of CNS depressants (alcohols, barbiturates, and benzodiazepines), as well as many other anesthesia-inducing compounds (adenosine, chloral hydrate, trichloroethanol, paraldehyde, nitrous oxide, enflurane, and isoflurane).