(1) We show that preservation of the correct PE carboxyl-terminal amino acid sequence, REDLK, allows the toxins containing TGF alpha carboxyl inserts to retain significant cytotoxicity against target cells, since another molecule (PE4E-TGF alpha-ILK) containing a nonfunctional carboxyl-terminal sequence was over 100-fold less active.
(2) We need to get back something of that ilk – where each team has three or four players from the home countries at the start of every match."
(3) Fashion's current preoccupation with art is effectively the death knell of the minimalist look – most art (Donald Judd and his ilk aside) is about getting messy.
(4) It is as honest as the report that emerged the same day from the world’s climate scientists, which demonstrated that if Exxon Mobil and its ilk keep their promise to dig up their reserves and burn them, then the planet will no longer function effectively.
(5) It's harder to romanticise living in such a dwelling in NYC – a Londoner can live in a bedsit and be reminded of Fleur and her ilk, but a New Yorker might be apt to think of SROs – but not impossible; in order to survive here, you have to develop the ability to romanticise just about anything.
(6) It's a little sweetly, wishy-washy in the body, but, for a beer of its ilk, it has a real thirst-quenching bitterness to it.
(7) It is a much more natural creed for rightists, like Charles, who dream of an ancient pastoral world where material goods were the prerogative of his ilk.
(8) Never mind that it was the overwhelmingly Tory shire votes of Jacob Rees-Mogg ’s ilk that swung the referendum, while two thirds of Labour voters were remainers.
(9) Some of us enjoyed it so much that we were all for Griffin and his ilk appearing on television all the time, purely in the spirit of political fair play, you understand.
(10) The trouble is that these supposed victims are very, very able to defend themselves and their ilk.
(11) You go to an amazing venue, there are influential people in the room of all ilks, people you wouldn’t normally meet in your day job.
(12) But it's clear that Chimpanzee and its ilk have strayed from the evolutionary path of nature documentary film-making.
(13) Forbes and his ilk have reached a sort of quantum theory of food: the more they look, the more they see.
(14) Democracy forgets you, no one cares what you think, and governments will spend a lot less on you and your ilk.
(15) Perhaps what Claire Alexander at the University of Manchester calls the “jovial bigotry” of Farage and his ilk has helped channel their rage.
(16) "If our critical culture handled films of this ilk with something other than kid gloves, we might not have to continually address these same, tired questions.
(17) But there is no need to apologise to somebody of that ilk.” Leicester are on an 11-game winless run and are bottom of the Premier League going into Saturday’s match at West Ham United, who are fourth.
(18) He told the Guardian: “I am delighted that Eddie Redmayne won [a Golden Globe for best actor], but we can’t just have a culture dominated by Eddie Redmayne and James Blunt and their ilk.
(19) A Mail Online columnist declared : “Next time you hear someone say we are safer IN the EU – remember Brussels.” And in an astonishing removal of guilt from the terrorist murderers, added: “Merkel – and her ilk – blew up Brussels.” I will vote to remain within the European Union, even though I am critical of its current incarnation and want to change it.
(20) Though frequently labelled super-injunctions, they are not of the same ilk as the case that prompted the original coining of the term, because it referred to the fact that the very existence of the injunction must remain secret.
Irk
Definition:
(v. t.) To weary; to give pain; to annoy; -- used only impersonally at present.
Example Sentences:
(1) When the rats were grouped into animals with mild (20%), moderate (50%), and severe (80%) reductions in maximal IRK activity, it was found that the mild and moderate defects could be reversed once the receptors were subjected to extensive autophosphorylation in vitro.
(2) We characterized the mechanism of IRK inhibition and studied whether it is the consequence of a glucose-induced stimulation of protein kinase C (PKC).
(3) 18 May 2014 New £69.4bn proposal, worth £55 a share, piles pressure on AstraZeneca's board to enter negotiations with Pfizer 19 May 2014 AstraZeneca board rejects Pfizer's final £69bn takeover bid , irking some large shareholders
(4) Reports of George’s stag do at Ristorante da Ivo near St Mark’s Square with the free £3,000 meal featuring six flavours of ice cream, including takeaway cartons, initially irked me.
(5) Joleon Lescott last weekend irked supporters by clumsily saying relegation was a “weight off the shoulders”.
(6) Wenger must be the only manager in football to be irked by reports that he will be offered a new deal.
(7) Walking by last Monday, Trump gestured towards an image of his inauguration crowd – a point that still irks him – and told reporters there would soon be an official statement about the future of his national security adviser, Michael Flynn.
(8) Blogger Yomi Adegoke said: "Thinly veiling vanity as philanthropy more than irks … the pretence these images are for anything other than an onslaught of 'natural beauty' acclamations, coupled with pats on the back for 'fighting the cause' makes the no makeup selfie mania even harder to stomach."
(9) We, therefore, conclude that glucose intolerance in aging could be attributed at least in part to acquired defects in the in vivo activation of the hepatic IRK, which results in reduced phosphorylation of its putative substrate pp180.
(10) But while agreeing that the results should not be exaggerated, D'Alimonte still thinks they indicate that the Five Star shine is wearing off among some voters - including those who were irked by the rambunctious figurehead's refusal to support a minority government led by the centre-left Democratic party (PD), thus forcing the PD to form a coalition with Berlusconi's centre-right.
(11) The corporation's power online and expanding digital TV and radio channels have irked beleaguered commercial rivals, resulting in an attack by James Murdoch, head of News Corporation in the UK.
(12) The home crowd turned their ire on the Hungarian referee Viktor Kassai – his decision to dismiss Piiroja for handball in the 76th minute particularly irked them – but they were deluding themselves if they thought he was to blame.
(13) Right now is not the time.” The midfielder refused to be drawn on suggestions that his team-mates were irked by his comments, and insisted the atmosphere among the squad in Brazil was similar to during the glorious Euro 2012 campaign.
(14) Hyperglycemia causes insulin-receptor kinase (IRK) resistance in fat cells.
(15) The comments irked the geologists' professional body, which was founded in 1807 as a dining club in a London pub.
(16) Philip Hammond appears to have irked the prime minister by making a sexist remark in cabinet, exposing the tensions at the highest level of government.
(17) Look, he’s the clear frontrunner, he’s been in six debates already, answered more questions from the media than any other candidate on the stage combined.” The Fox News press release that irked Trump and led to his withdrawal read: “We learned from a secret back channel that the Ayatollah and Putin both intend to treat Donald Trump unfairly when they meet with him if he becomes president – a nefarious source tells us that Trump has his own secret plan to replace the Cabinet with his Twitter followers to see if he should even go to those meetings.” Trump derided it as “a wise guy press release .
(18) To determine whether defects in insulin receptor kinase (IRK) activity or in the phosphorylation of its physiological substrates underlie this age-related phenomenon, young (2-3 months old) and old (24-27 months old) Wistar rats were studied.
(19) Field has already irked the medallion stallion with some low blows before the bell has rung, but it looks doubtful whether punches will be pulled for the number crunchers.
(20) Linehan, who turned 44 last week, is irked by the persistence of the idea that the sitcom that brought him and Arthur Mathews to the attention of millions has canned laughter on it.