(a.) Destitute of strength, whether of body or mind; feeble; impotent; esp., mentally wea; feeble-minded; as, hospitals for the imbecile and insane.
(n.) One destitute of strength; esp., one of feeble mind.
(v. t.) To weaken; to make imbecile; as, to imbecile men's courage.
Example Sentences:
(1) Infantile delivery also frequently serves to take the curse off self-publicity; sleight of hand for those who find "my programme is on BBC2 tonight" too presumptuous and exposing, and prefer to cower behind the low-status imbecility of "I done rote a fingy for da tellybox!"
(2) By this shape of holidays the partical sphere of the process of training and education, namely the qualification of those oligophren ones in spending an ingenious leisure, should be noticed and contributed to educating those imbecile boys and girls, who are participating their holidays in a camp for their "relative independence*.
(3) Fifty-six patients with cerebral atherosclerosis and epileptiform symptomatology presented an organic defect with signs of lacunar imbecility and atherosclerotic asthenia.
(4) Report on a 5 year old girl with the caracteristic features of the partial trisomy of the short arm of a chromosome no.4: short stature, microcephaly, hydrocephaly, enophthalmus, bulbous nose, deep set malformed ears, hypertrichosis, brachydactyly, hypoplastic ribs, abnormal EEG, imbecility.
(5) "This is imbecilic," said Jean-Yves Oussedik, a historian, puffing his pipe outside the literary cafe Les Deux Magots.
(6) Target London , a folio of 18 posters, bleakly satirised the Thatcher government’s Protect and Survive nuclear attack directives; the critic Richard Cork described the series as the “most hard-hitting attack on government imbecility”.
(7) And there I was, week after week, paid a pittance to jeer at the Smith regime's imbecilities.
(8) It's time to address the public as competent grown-ups and not as imbeciles.
(9) As a late sequelae, there was one patient with intrahepatic block and portal hypertension and one with encephalopathy and imbecility.
(10) Treatment under general anesthesia is inevitably indicated in imbeciles, the feeble-minded, spastics, epileptics, and sometimes in mongoloids.
(11) But before he was a candidate, he was just a visible idiot, and Jon Stewart’s version of him as a knuckle-dragging Queens County imbecile has given us tremendous joy over the years.
(12) The disease had not been diagnosed during life despite imbecility since early childhood and the presence of guiding peripheral symptoms in the form of Pringle's disease.
(13) Meanwhile, because we no longer understand anything unless it is filtered through the prism of the Premier League, various newspapers have already dubbed May's poll " the Wags election " – a classification that underscores the almost infinite creativity of the British media, which have apparently now given up so emphatically that they are content to shoehorn absolutely all human experience into one of four or five pop-cultural tropes, the easier for the voters it apparently regards as imbeciles to understand.
(14) In broadcast interviews, ministers carefully dodge the delivery of any information at all; they would rather sound imbecilic, as if they understood very little and knew even less, than run the risk of having said anything of import.
(15) The differential-diagnostic criteria show the difference of the episodic psychoses of imbeciles from schizophrenias (grafted schizophrenias).
(16) The experience gathered thus far shows that the method presented by the author in his present paper enables the capacity and development of imbecile and abnormality feeble children and juveniles to be diagnosed.
(17) When some highly debile, or imbecile and idiotic children and adolescents refuse to cooperate during the stomatological attendance, the pedopsychiatric consultation fails.
(18) Yet social media is the last remaining British arena in which social mobility flourishes, where imbecilic irrelevances are fast-tracked to positions of extraordinary power by whichever MP or university professor or serious campaigner has decided to give their bile a platform on the news.
(19) Statistically significant differences were established in the values of integrative mark estimations of patients with pronounced debility, of those with mild, medium and profound imbecility.
(20) Patients with pronounced tetrapareses and contractures in all the joints, grave hyperkinesias in all the four extremities, and imbecility were classed with disability group I: those with pronounced para-, hemi-, and tetrapareses, extensive hyperkinesias, combination of the motor disorders with debility were placed into disability group II.
Oaf
Definition:
(n.) Originally, an elf's child; a changeling left by fairies or goblins; hence, a deformed or foolish child; a simpleton; an idiot.
Example Sentences:
(1) Big OAF was converted to little OAF by equilibration in 1 M NaCl or 2 M urea.
(2) Outside, there’s no sign of life except one bearded oaf on a chopper and a kid at the back door, holding a picture of Hot Fuss-era Brandon Flowers , praying for a brief encounter.
(3) The effect of interleukin-1 beta, the major component of osteoclast-activating factor (OAF), on bone formation by fetal rat osteoblast-rich cells was investigated.
(4) Recent studies show that osteoclast activating factor (OAF) is homologous to IL-1B.
(5) The resorption response to OAF also resembles that of PTH in having a steep dose response curve and being only transiently inhibited by calcitonin and partially inhibited by increasing medium phosphate concentration.
(6) Spleen cells treated with mitogens produce a potent bone-resorbing factor called osteoclast-activating factor (OAF).
(7) In contrast, supernatant fluids from concanavalin A (Con-A)-activated murine spleen cell cultures (murine osteoclast-activating factor; OAF) consistently and significantly induced a 3- to 5-fold stimulation of bone resorption in this system.
(8) OAF production is probably related to the nature of hydrocarbons in the air.
(9) Calcium release was significantly increased for all agents between 12 and 24 h. It is concluded that bone resorption by 1,25(OH)2D3, OAF, and PGE2 is mediated primarily by increased activity of existing osteoclasts similar to PTH activation.
(10) The presence of bactericidal compounds (open air factor = OAF) could be demonstrated on several days and quantitated in relative units of OAF concentration.
(11) The current studies were designed to produce monoclonal antibodies against OAF for use in the subsequent design of immunoassays for OAF in clinical samples.
(12) In this study we examined the relationship between the lymphocyte and monocyte in OAF production.
(13) The lymphokine osteoclast-activating factor (OAF) was purified to homogeneity.
(14) These results indicate that prostaglandin synthesis is necessary for OAF production.
(15) Are there really "nine sleeps 'til new Who" you gurgling oaf?
(16) Bones from mi mice showed a generalized resorption defect with decreased spontaneous or control resorption and failure to respond to parathyroid hormone (PTH), prostaglandin E2, 1,25 dihydroxy vitamin D3, vitamin A, or osteoclast activating factor (OAF) from human peripheral leukocytes or mouse spleen cells.
(17) OAF release was stimulated by pokeweed mitogen and concanavalin A as well as by phytohemagglutinin.
(18) When PGE1 and PGE2 (0.1 microM) were added exogenously to the enriched lymphocyte population, OAF release occurred after stimulation with PHA.
(19) We have further characterized osteoclast activating factor (OAF) using a bioassay for bone resorption which utilizes the release of previously incorporated (45)Ca from fetal rat long bones in organ culture.
(20) The demonstration of increased osteoclast activating factor (OAF) derived from the cultured myeloma cells from each case suggests that the secretion of OAF and immunoglobulin are unrelated.