(v. t.) Full of, or burdened by, import; charged with great interests; restless; anxious.
(v. t.) Carrying or possessing weight or consequence; of valuable content or bearing; significant; weighty.
(v. t.) Bearing on; forcible; driving.
(v. t.) Importunate; pressing; urgent.
Example Sentences:
(1) CT appears to yield important diagnostic contribution to preoperative staging.
(2) This paper discusses the typical echocardiographic patterns of a variety of important conditions concerning the mitral valve, the left ventricle, the interatrial and interventricular septum as well as the influence of respiration on the performance of echocardiograms.
(3) However, medicines have an important part to play, and it is now generally agreed that for the very poor populations medicines should be restricted to those on an 'essential drugs list' and should be made available as cheaply as possible.
(4) Glucocorticoids have numerous effects some of which are permissive; steroids are thus important not only for what they do, but also for what they permit or enable other hormones and signal molecules to do.
(5) Trifluoroacetylated rabbit serum albumin was 5 times more reactive with these antibodies and thus more antigenic than the homologous acetylated moiety confirming the importance of the trifluoromethyl moiety as an epitope in the immunogen in vivo.
(6) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
(7) However it is important to recognize these cysts so that correct surgical management is offered to the patient.
(8) gamma-Aminobutyric acid (GABA) and glutamate release from the treated side was higher than the control value during the first 2-3 h, a result indicating an important role of glial cells in the inactivation of released transmitter.
(9) Under blood preservation conditions the difference of the rates of ATP-production and -consumption is the most important factor for a high ATP-level over long periods.
(10) This finding is of major importance for persons treated with diltiazem who engage in sport.
(11) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
(12) Because of the dearth of epidemiological clues as to causation, studies with experimental animal models assume greater importance.
(13) The severity and site of hypertrophy is important in determining the clinical picture and the natural history of hypertrophic cardiomyopathy (HCM).
(14) As prolongation of the action potential by TEA facilitates preferentially the hormone release evoked by low (ineffective) frequencies, it is suggested that a frequency-dependent broadening of action potentials which reportedly occurs on neurosecretory neurones may play an important role in the frequency-dependent facilitation of hormone release from the rat neurohypophysis.
(15) Nutritional factors or environmental toxins have important effects on CNS degenerative changes.
(16) Moreover, homozygous deletion of the FMS gene may be an important event in the genesis of the MDS variant 5q- syndrome.
(17) Importantly, these characteristics were strong predictors of subsequent mortality.
(18) As the requirements to store and display these images increase, the following questions become important: (a) What methods can be used to ensure that information given to the physician represents the originally acquired data?
(19) Periosteal chondroma is an uncommon benign cartilagenous lesion, and its importance lies primarily in its characteristic radiographic and pathologic appearance which should be of assistance in the differential diagnosis of eccentric lesions of bones.
(20) As important providers of health care education, nurses need to be fully informed of the research findings relevant to effective interventions designed to motivate health-related behavior change.
Meiosis
Definition:
(n.) Diminution; a species of hyperbole, representing a thing as being less than it really is.
Example Sentences:
(1) To this end, a meiosis-defective mating-type mutation was used as a marker for the plus segment, by taking advantage of its suppressibility by a nonsense suppressor.
(2) When multiple probes were informative, the meiotic exchange points for each meiosis were located in individual families.
(3) This observation suggests that testosterone acts to inhibit meiosis at a site beyond the function of the puromycin-sensitive proteins or that testosterone causes a reduction in the turnover rate of these proteins.
(4) Commitment to meiosis occurs during the prezygotene interval at about the time when S-phase replication is completed.
(5) Meiosis is too complex to have arisen at once full blown and a stepwise scheme is proposed for its evolution, where each step is believed to have provided an immediate selective advantage: (1) The first step in this tentative sequence is the development of a haploidization process by means of a rapid series of mitotic non-disjunctions, turned on under conditions where haploidy is favored.
(6) Recently, cDNA clones encoding several bovine CKI isoforms have been sequenced that show high sequence identity to the HRR25 gene product of the budding yeast Saccharomyces cerevisiae; HRR25 is required for normal cellular growth, nuclear segregation, DNA repair, and meiosis.
(7) They proceed through meiosis normally, as judged by the occurrence of meiotic recombination, the production of haploid nuclei, and the formation of multinucleate cells visible after Giemsa staining.
(8) In continuation of the research on male human meiosis within the study of pachytene bivalents, results from the analysis of 125 cells are presented.
(9) The absence of these mRNAs in mitosis and their disappearance at 4 hr and later in meiosis suggest that the rec7 and rec8 gene products may be involved primarily in the early steps of meiotic recombination in S. pombe.
(10) This trisomy arose through aberrant segregation of translocation chromosome during meiosis in the patient's mother, who is a balanced heterozygote for a complex translocation involving chromosomes 9, 21 and 22.
(11) Chemicals were injected into mice at the MI (meiosis I) stage or 3 hours before the MI stage in order to examine their toxicity.
(12) In the immunogold staining assay a post-fixation and nuclear staining procedure was developed which allowed identification of isolated germ cells, revealing clearly, for all seven MAbs, that the determinants were expressed on germ cells but not on somatic cells and, for WCS 7, 11 and 12 only, that the determinants first appeared on small spermatogonia prior to meiosis.
(13) A 'small' CG-free area of the cortex, with prominent cytoplasmic protrusions, appeared twice during the progression of meiosis.
(14) An attractive explanation for these results is that long tandem arrays of simple repeated sequences are generated at high frequency throughout the genome and that they are retained for a longer time on the Y chromosome due to the absence of homologous pairing at meiosis.
(15) Expression of one of the three genes was found to be limited to a single cell type during the 5-6 day period from late meiosis to immature pollen formation.
(16) Analysis of RNA from different developmental stages and from enriched populations of spermatogenic cells revealed that this gene is expressed during the prophase stage of meiosis.
(17) In fission yeast the ability to undergo meiosis and sporulation is conferred by the matP+ and matM+ genes of the mating-type locus.
(18) The binding of in vivo labeled RNA to the corresponding DNAs increased 3- to 12-fold at the time of meiosis I, in parallel with the accumulation of the SPR transcripts.
(19) It was concluded that meiosis and spore formation in Saccharomycopsis lipolytica seem to represent parallel and coordinated processes which generally resemble those recorded for Saccharomyces cerevisiae and Hansenula species.
(20) Neither meiosis nor mutagenesis increased the revertant frequency, nor did incubation at elevated temperatures lower it.